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Search Result

Search Results for " ais "

14

Compounds

2

Natural Products

4

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T74570 SIAIS164018
SIAIS164018, a PROTAC-based ALK and EGFR degrader derived from Brigatinib, exhibits IC50 values of 2.5 nM for ALK and 6.6 nM for ALK G1202R. It significantly hampers cancer cell migration and invasion, induces G1 cell cy...
T77969 SIAIS100 TFA Bcr-Abl
SIAIS100 TFA is a potent BCR-ABL PROTAC degrader, exhibiting a DC50 of 2.7 nM. It is utilized in the research of chronic myeloid leukemia (CML) [1].
T74489 SIAIS117
SIAIS117, a potent Brigatinib-PROTAC degrader, effectively degrades the ALK G1202R point mutation through its design based on Brigatinib and VHL-1 conjunction. It inhibits the proliferation of SR and H2228 cancer cell li...
T126171 Germanaism B
Germanaism B is a useful organic compound for research related to life sciences. The catalog number is T126171 and the CAS number is 123648-56-6.
T12907 SIAIS178 Others , Bcr-Abl
SIAIS178 is a potent and selective degrader of BCR-ABL based on PROTAC technology (IC50 of 24 nM).
T75012 SIAIS100
SIAIS100, a potent BCR-ABL PROTAC degrader, demonstrates a DC50 value of 2.7 nM, highlighting its efficacy. It is primarily utilized in the investigation of chronic myeloid leukemia (CML) [1].
T77942 SIAIS164018 hydrochloride PROTACs
SIAIS164018 hydrochloride is a PROTAC-based degrader targeting ALK and EGFR, exhibiting IC50 values of 2.5 nM for ALK and 6.6 nM for ALK G1202R. It effectively suppresses cancer cell migration and invasion, induces G1 ce...
T24983 5-Deazaisofolic acid
5-Deazaisofolic acid shows potent antitumor activity.
TNU1107 4-Anhydro-2-O-(2,4-dimethoxybenzoyl)-3,5-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-4-thio-D-ribitol
4-Anhydro-2-O-(2,4-dimethoxybenzoyl)-3,5-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-4-thio-D-ribitol is a Carbohydrate Derivative.
T67388 N-(1-((6aR,8R,9aR)-9-Cyano-9-hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide
N-(1-((6aR,8R,9aR)-9-Cyano-9-hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide is a useful organic compound for research related to life sci...
TNU1108 (R)-1,4-Anhydro-2-O-(2,4-dimethoxybenzoyl)-3,5-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-4-sulfinyl-D-ribitol
Carbohydrate Derivatives; Ready for glycosylation
T124895 Isoneobavaisoflavone
Isoneobavaisoflavone is a useful organic compound for research related to life sciences and the catalog number is T124895.
T19659 Annaosanchun YC6,YC-6,YC 6 Others , AMPK
Annaosanchun (YC-6) is potentially for the treatment of acute ischemic stroke (AIS).
T28438 2-(1-hydroxypentyl)benzoic Acid dl-PHPB
Potassium-Hydroxypentyl Benzoate is a drug potentially for the treatment of acute ischemic stroke (AIS)
Cat No. Product Name Synonyms Targets
T6S0139 Neobavaisoflavone Apoptosis , DNA/RNA Synthesis
1. Neobavaisoflavone is isolated as a DNA polymerase inhibitor. 2. Neobavaisoflavone might be a potential anabolic agent to treat bone loss-associated diseases. 3. Neobavaisoflavone has anti-inflammatory activity, can si...
TN2219 Sophoraisoflavone A MRP , Antifection
Sophoraisoflavone A is a potential MRP inhibitor; it is also an inhibitor of germ tube growth in the AM fungus Gigaspora margarita, it strongly inhibited germ tube growth at 1.25 ug/disc. Sophoraisoflavone A shows inhibi...

Natural Products

Neobavaisoflavone
T6S0139
Synonym:
Target: Apoptosis, DNA/RNA Synthesis
Sophoraisoflavone A
TN2219
Synonym:
Target: MRP, Antifection

Recombinant Proteins

Species：
HBV-D (2)
Human (2)
Expression System：
Baculovirus Insect Cells (2)
E. coli (2)
Tag：
C-His (1)
His (1)
His, GST (1)
N-6xHis-SUMO (1)
Cat No. Product Name Species Expression System
TMPY-02651 P63 Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
Tumor protein p63 is a protein also known as transformation-related protein 63, TP63, and p63. Tumor protein p63 / p63 is a member of the p53 family of transcription factors whose members P53, p63, and p73 have similar f...
TMPY-02952 SIAE Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
Sialate O-acetylesterase belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. It is widely expressed with high expression in the testis, prostate, and colon. The systematic name of th...
TMPY-05822 Hepatitis B Virus (HBV)(ayw/France/Tiollais/1979) Capsid protein (His) HBV-D E. coli
Hepatitis B virus (HBV) capsid assembly is a critical step in the propagation of the virus and is mediated by the core protein. The first cytoplasmic step in the formation of an infectious HBV virion is the formation of ...
TMPH-00807 HBV-D subtype ayw (isolate France/Tiollais/1979) Protein X (His & SUMO) HBV-D E. coli
HBV-D subtype ayw (isolate France/Tiollais/1979) Protein X (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 32.6 kDa and the accession number is P03165.
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