ache-in-10 — TargetMol Chemicals

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Search Results for " ache-in-10 "

Compounds

Cat No.	Product Name	Targets
T62743	AChE-IN-10
	AChE-IN-10 (Compound 24r) is a potent inhibitor of AChE with an IC50 value of 2.4 nM. AChE-IN-10 decreases amyloid aggregation in the presence of AChE. AChE-IN-10 exhibited a potent inhibitory effect on AChE, reducing ta...
T61969	AChE/BChE-IN-10	AChR , AChE
	AChE/BChE-IN-10 is a potent dual inhibitor of AChE and BChE with IC50 values of 0.176, and 0.47 μM, respectively. AChE/BChE-IN-10 exhibits good blood brain barrier permeability. AChE/BChE-IN-10 can inhibit Aβ-aggregation...	AChR , AChE
T62541	AChE-IN-22
	AChE-IN-22 (compound 10q) is a selective inhibitor of acetylcholinesterase (AChE) that acts on both AChE (IC50: 0.88 μM) and BuChE (IC50: 10 μM). AChE-IN-22 binds to both the CAS (catalytic active site) and PAS (peripher...
T78860	MAO-B-IN-24	Monoamine Oxidase
	MAO-B-IN-24 (compound 11h) is a selective, reversible, competitive inhibitor of MAO-B with an IC50 value of 1.60 μM. It also exhibits inhibitory effects on MAO-A with an IC50 of 22.42 μM. At a concentration of 10 μM, MAO...	Monoamine Oxidase
TN4286	Isodunnianol	NOS , NF-κB , ROS , AChR
	Isodunnianol exhibits anti-AChE activity with an IC50 value of 13.0 uM; it also exhibits neurite outgrowth-promoting activity at the concentration ranging from 0.1 to 10 uM in the primary cultured rat cortical neurons. I...	NOS , NF-κB , ROS , AChR
T35975	6,9-Dichloro-1,2,3,4-tetrahydroacridine
	6,9-Dichloro-1,2,3,4-tetrahydroacridine is a synthetic intermediate in the synthesis of tacrine-based acetylcholinesterase (AChE) inhibitors.1It is also an intermediate in the synthesis of multifunctional tacrine hybrids...