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Search Results for " 5-ht1b "

20

Compounds

Cat No. Product Name Synonyms Targets
TQ0311 GSK163090 Dopamine Receptor , 5-HT Receptor
GSK163090 is a specific and orally active 5-HT1A/B/D receptor antagonist (pKis: 9.4/8.5/9.7, and 6.3/6.7 for 5-HT1A/B/D, and dopamine D2/D3).
T8593 RU 24969 5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole 5-HT Receptor
RU 24969 (5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole) is a selective agonist of 5-HT1A and 5-HT1B receptors.
T22236 Alprenolol hydrochloride 5-HT Receptor
Alprenolol hydrochloride is a non-selective blocker of beta, and also is a antagonist of5-HT1A receptor.
T8737 GR 125743 5-HT Receptor
GR 125743 is a novel antagonist of 5-HT1B/1D receptor.
T0203 Sumatriptan succinate GR 43175 5-HT Receptor
Sumatriptan succinate (GR 43175), a serotonin1 (5-HT1) receptor agonist, is used in the acute treatment of a migraine headache.
T11326 Frovatriptan succinate hydrate Frovelan,Frova 5-HT Receptor
Frovatriptan succinate hydrate (Frova) is effective in treating the full spectrum of migraine including the associated symptoms of nausea, vomiting, photophobia, and phonophobia. Frovatriptan succinate hydrate can also b...
T11075 Donitriptan 5-HT Receptor
Donitriptan is a 5-HT receptor agonist with pKis of 9.4 and 9.3 for 5-HT1B and 5-HT1D, respectively.
T7498 Eltoprazine hydrochloride DU 28853 hydrochloride 5-HT Receptor
Eltoprazine hydrochloride (DU 28853 hydrochloride) is a partial agonist at serotonin 5-HT1A, 5-HT1B, and 5-HT2B receptors (Ki value of 40, 52, and 81 nM, respectively).
T12861 SB-277011 SB-277011A Dopamine Receptor
SB-277011 (SB-277011A) is a specific antagonist of the dopamine D3 receptor with pKi values of 8.0, 6.0, 5.0, and <5.2 for D3 receptor, D2 receptor, 5-HT1D, and 5-HT1B respectively.
T22576 Anpirtoline hydrochloride Others
5-HT1B receptor agonist
T22808 GR 46611 5-HT Receptor
GR 46611 is a selective 5-HT1B and 5-HT1D receptor agonist and can be used in studies about the treatment of epilepsy.
T12841 SB-224289 hydrochloride SB-224289A 5-HT Receptor
SB-224289 hydrochloride (SB-224289A) is a selective antagonist of 5-HT1B receptor, with anxiolytic effect.
T12847 SB-616234-A SB-616234A 5-HT Receptor
SB-616234A is a selective and orally bioavailable antagonist of 5-HT1B receptor, with anxiolytic and antidepressant activity.
T15414 GR 113808 GR-113808 5-HT Receptor
GR 113808 is a selective 5-HT4 receptor antagonist that inhibits 5-HT1B, 5-HT2A, 5-HT2C, and 5-HT3 receptors, and attenuates dopamine release.
T0216 Eletriptan hydrobromide Eletriptan HBr,UK-116044 5-HT Receptor
Eletriptan hydrobromide (Eletriptan HBr) is an orally active agonist with specific affinity for the 5-hydroxytriptamine1B/1D receptor.
T22689 CP94253 hydrochloride CP 94253 hydrochloride Others , 5-HT Receptor
CP94253 hydrochloride (CP 94253 hydrochloride) is a potent, selective and centrally active agonist of 5-HT1B receptor with Ki of 2 nM. The Kis are 89, 49, 860, and 1600 nM for 5-HT1A, 5-HT1D, 5-HT1C and 5-HT2 receptors, ...
T6423 BRL-15572 dihydrochloride BRL 15573 dihydrochloride 5-HT Receptor
BRL-15572 dihydrochloride (BRL 15573 dihydrochloride) is a 5-HT1D receptor antagonist with pKi of 7.9, also shows a considerable affinity at 5-HT1A and 5-HT2B receptors, exhibiting 60-fold selectivity over 5-HT1B recepto...
T2317 Almotriptan Malate LAS 31416,PNU180638 5-HT Receptor
Almotriptan Malate (PNU180638), a selective 5-HT1B/1D receptor agonist, is used in the therapy of Migraine attacks in adults.
T21666 Donitriptan hydrochloride Donitriptan HCl,Donitriptan monohydrochloride 5-HT Receptor
Donitriptan hydrochloride (Donitriptan monohydrochloride) is a potent, high efficacy agonist of 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectively
T50039 3-(2-aminopropyl)phenol hydrochloride Others
3-(2-aminopropyl)phenol hydrochloride is a phenethylamine analog used as a molecular structural unit. It is a psychoactive drug that is a partial agonist at several serotonin receptors, including 5-HT1A, 5-HT1B, and 5-HT...
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