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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TQ0311 | GSK163090 | Dopamine Receptor , 5-HT Receptor | |
GSK163090 is a specific and orally active 5-HT1A/B/D receptor antagonist (pKis: 9.4/8.5/9.7, and 6.3/6.7 for 5-HT1A/B/D, and dopamine D2/D3). | |||
T8593 | RU 24969 | 5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole | 5-HT Receptor |
RU 24969 (5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole) is a selective agonist of 5-HT1A and 5-HT1B receptors. | |||
T22236 | Alprenolol hydrochloride | 5-HT Receptor | |
Alprenolol hydrochloride is a non-selective blocker of beta, and also is a antagonist of5-HT1A receptor. | |||
T8737 | GR 125743 | 5-HT Receptor | |
GR 125743 is a novel antagonist of 5-HT1B/1D receptor. | |||
T0203 | Sumatriptan succinate | GR 43175 | 5-HT Receptor |
Sumatriptan succinate (GR 43175), a serotonin1 (5-HT1) receptor agonist, is used in the acute treatment of a migraine headache. | |||
T11326 | Frovatriptan succinate hydrate | Frovelan,Frova | 5-HT Receptor |
Frovatriptan succinate hydrate (Frova) is effective in treating the full spectrum of migraine including the associated symptoms of nausea, vomiting, photophobia, and phonophobia. Frovatriptan succinate hydrate can also b... | |||
T11075 | Donitriptan | 5-HT Receptor | |
Donitriptan is a 5-HT receptor agonist with pKis of 9.4 and 9.3 for 5-HT1B and 5-HT1D, respectively. | |||
T7498 | Eltoprazine hydrochloride | DU 28853 hydrochloride | 5-HT Receptor |
Eltoprazine hydrochloride (DU 28853 hydrochloride) is a partial agonist at serotonin 5-HT1A, 5-HT1B, and 5-HT2B receptors (Ki value of 40, 52, and 81 nM, respectively). | |||
T12861 | SB-277011 | SB-277011A | Dopamine Receptor |
SB-277011 (SB-277011A) is a specific antagonist of the dopamine D3 receptor with pKi values of 8.0, 6.0, 5.0, and <5.2 for D3 receptor, D2 receptor, 5-HT1D, and 5-HT1B respectively. | |||
T22576 | Anpirtoline hydrochloride | Others | |
5-HT1B receptor agonist | |||
T22808 | GR 46611 | 5-HT Receptor | |
GR 46611 is a selective 5-HT1B and 5-HT1D receptor agonist and can be used in studies about the treatment of epilepsy. | |||
T12841 | SB-224289 hydrochloride | SB-224289A | 5-HT Receptor |
SB-224289 hydrochloride (SB-224289A) is a selective antagonist of 5-HT1B receptor, with anxiolytic effect. | |||
T12847 | SB-616234-A | SB-616234A | 5-HT Receptor |
SB-616234A is a selective and orally bioavailable antagonist of 5-HT1B receptor, with anxiolytic and antidepressant activity. | |||
T15414 | GR 113808 | GR-113808 | 5-HT Receptor |
GR 113808 is a selective 5-HT4 receptor antagonist that inhibits 5-HT1B, 5-HT2A, 5-HT2C, and 5-HT3 receptors, and attenuates dopamine release. | |||
T0216 | Eletriptan hydrobromide | Eletriptan HBr,UK-116044 | 5-HT Receptor |
Eletriptan hydrobromide (Eletriptan HBr) is an orally active agonist with specific affinity for the 5-hydroxytriptamine1B/1D receptor. | |||
T22689 | CP94253 hydrochloride | CP 94253 hydrochloride | Others , 5-HT Receptor |
CP94253 hydrochloride (CP 94253 hydrochloride) is a potent, selective and centrally active agonist of 5-HT1B receptor with Ki of 2 nM. The Kis are 89, 49, 860, and 1600 nM for 5-HT1A, 5-HT1D, 5-HT1C and 5-HT2 receptors, ... | |||
T6423 | BRL-15572 dihydrochloride | BRL 15573 dihydrochloride | 5-HT Receptor |
BRL-15572 dihydrochloride (BRL 15573 dihydrochloride) is a 5-HT1D receptor antagonist with pKi of 7.9, also shows a considerable affinity at 5-HT1A and 5-HT2B receptors, exhibiting 60-fold selectivity over 5-HT1B recepto... | |||
T2317 | Almotriptan Malate | LAS 31416,PNU180638 | 5-HT Receptor |
Almotriptan Malate (PNU180638), a selective 5-HT1B/1D receptor agonist, is used in the therapy of Migraine attacks in adults. | |||
T21666 | Donitriptan hydrochloride | Donitriptan HCl,Donitriptan monohydrochloride | 5-HT Receptor |
Donitriptan hydrochloride (Donitriptan monohydrochloride) is a potent, high efficacy agonist of 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectively | |||
T50039 | 3-(2-aminopropyl)phenol hydrochloride | Others | |
3-(2-aminopropyl)phenol hydrochloride is a phenethylamine analog used as a molecular structural unit. It is a psychoactive drug that is a partial agonist at several serotonin receptors, including 5-HT1A, 5-HT1B, and 5-HT... |