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G Protein-Coupled Receptors, GPCRs

G protein-coupled receptors (GPCRs) form a large group of evolutionarily related proteins that are cell surface receptors that detect molecules outside the cell and activate cellular responses. GPCRs are found only in eukaryotes, including yeast, and choanoflagellates. The ligands that bind and activate these receptors include light-sensitive compounds, odors, pheromones, hormones, and neurotransmitters.

GPCRs are involved in many diseases such as mental, metabolic including endocrinological disorders, immunological including viral infections, cardiovascular, inflammatory, senses disorders, and cancer. Therefore, GPCRs are an important drug target and approximately 34% of all Food and Drug Administration (FDA) approved drugs target 108 members of this family.

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Species
Cynomolgus (2)
Human (41)
Mouse (10)
Rat (2)
Expression System
Baculovirus Insect Cells (1)
CHO Cells (1)
E. coli (2)
HEK293 Cells (51)
Tag
(4)
C-6xHis (1)
C-6xHis-Avi (1)
C-Flag (1)
C-His (17)
C-His & N-Flag (2)
C-His-Avi (1)
C-hFc (12)
C-mFc (4)
GFP (1)
N-His (2)
N-hFc (3)
Tag Free (6)
Cat No. product name / Synonyms Species Expression System
TMPY-06360 SSTR2/SSTR2B Protein-VLP, Human, Recombinant
SSTR2/SSTR2B Protein-VLP, Human, Recombinant
Human HEK293 Cells
SSTR2/SSTR2B Protein-VLP, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 40.01 kDa and the accession number is P308...
TMPY-06364 SSTR2/SSTR2A Protein-VLP, Human, Recombinant
SSTR2/SSTR2A Protein-VLP, Human, Recombinant
Human HEK293 Cells
SSTR2/SSTR2A Protein-VLP, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 41.34 kDa and the accession number is P308...
TMPY-06494 GPRC5D Protein-VLP, Human, Recombinant
GPRC5D Protein-VLP, Human, Recombinant
Human HEK293 Cells
GPRC5D Protein-VLP, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 38.80 kDa and the accession number is Q9NZD1-1.
TMPY-06553 CXCR4 Protein, Human, Recombinant
CXCR4 Protein, Human, Recombinant
Human HEK293 Cells
CXCR4 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 39.75 kDa and the accession number is P61073-1.
TMPY-06601 GPRC5D Protein, Human, Recombinant, Biotinylated
GPRC5D Protein, Human, Recombinant, Biotinylated
Human HEK293 Cells
GPRC5D Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 38.80 kDa and the accession number is ...
TMPY-06623 CB2/CNR2 Protein, Human, Recombinant
CB2/CNR2 Protein, Human, Recombinant
Human HEK293 Cells
Genetic variants within the CNR2 gene encoding the cannabinoid receptor CB2 are associated with osteoporosis and low bone mineral density (BMD) in case-control s...
TMPY-06697 FZD3/frizzled 3 Protein, Human, Recombinant (His)
FZD3/frizzled 3 Protein, Human, Recombinant (His)
Human HEK293 Cells
FZD3/frizzled 3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.79 kDa and the access...
TMPY-06718 GPRC5D Protein, Human, Recombinant (His & FLAG), Detergent
GPRC5D Protein, Human, Recombinant (His & FLAG), Detergent
Human HEK293 Cells
GPRC5D Protein, Human, Recombinant (His & FLAG), Detergent is expressed in HEK293 mammalian cells with His and Flag tag. The predicted molecular weight is 32.83 ...
TMPY-06719 GPRC5D Protein, Human, Recombinant (His & FLAG)
GPRC5D Protein, Human, Recombinant (His & FLAG)
Human HEK293 Cells
GPRC5D Protein, Human, Recombinant (His & FLAG) is expressed in HEK293 mammalian cells with His and Flag tag. The predicted molecular weight is 32.83 kDa and the...
TMPY-06806 GPRC5D Protein-VLP, Human, Recombinant (GFP)
GPRC5D Protein-VLP, Human, Recombinant (GFP)
Human HEK293 Cells
GPRC5D Protein, Human, Recombinant, Fluorescent is expressed in HEK293 mammalian cells. The predicted molecular weight is 65.81 kDa and the accession number is Q...
TMPY-06807 GPRC5D Protein-VLP, Mouse, Recombinant (Flag)
GPRC5D Protein-VLP, Mouse, Recombinant (Flag)
Mouse HEK293 Cells
GPRC5D Protein, Mouse, Recombinant (Flag) is expressed in HEK293 mammalian cells with Flag tag. The predicted molecular weight is 35.8 kDa and the accession numb...
TMPY-06864 GLP1R Protein, Human, Recombinant (His & Avi)
GLP1R Protein, Human, Recombinant (His & Avi)
Human HEK293 Cells
Glucagon-like peptide (GLP)-1 receptor is encoded by GLP1R. GLP1R plays a critical role in mediating the biological actions of GLP1 in mammals and fish. The neur...
TMPY-01469 Frizzled 5 Protein, Human, Recombinant (His)
Frizzled 5 Protein, Human, Recombinant (His)
Human HEK293 Cells
Frizzled 5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.6 kDa and the accession nu...
TMPY-00908 Renin Protein, Human, Recombinant (His)
Renin Protein, Human, Recombinant (His)
Human HEK293 Cells
Renin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.7 kDa and the accession number ...
TMPY-04853 TSHR Protein, Human, Recombinant (His)
TSHR Protein, Human, Recombinant (His)
Human Baculovirus Insect Cells
Thyroid-stimulating hormone (TSH) is secreted by the pituitary gland and promotes thyroid growth and function, with increased TSH levels typically associated wit...
SSTR2/SSTR2B Protein-VLP, Human, Recombinant
TMPY-06360
SSTR2/SSTR2B Protein-VLP, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 40.01 kDa and the accession number is P308...
SSTR2/SSTR2A Protein-VLP, Human, Recombinant
TMPY-06364
SSTR2/SSTR2A Protein-VLP, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 41.34 kDa and the accession number is P308...
GPRC5D Protein-VLP, Human, Recombinant
TMPY-06494
GPRC5D Protein-VLP, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 38.80 kDa and the accession number is Q9NZD1-1.
CXCR4 Protein, Human, Recombinant
TMPY-06553
CXCR4 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 39.75 kDa and the accession number is P61073-1.
GPRC5D Protein, Human, Recombinant, Biotinylated
TMPY-06601
GPRC5D Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 38.80 kDa and the accession number is ...
CB2/CNR2 Protein, Human, Recombinant
TMPY-06623
Genetic variants within the CNR2 gene encoding the cannabinoid receptor CB2 are associated with osteoporosis and low bone mineral density (BMD) in case-control s...
FZD3/frizzled 3 Protein, Human, Recombinant (His)
TMPY-06697
FZD3/frizzled 3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.79 kDa and the access...
GPRC5D Protein, Human, Recombinant (His & FLAG), Detergent
TMPY-06718
GPRC5D Protein, Human, Recombinant (His & FLAG), Detergent is expressed in HEK293 mammalian cells with His and Flag tag. The predicted molecular weight is 32.83 ...
GPRC5D Protein, Human, Recombinant (His & FLAG)
TMPY-06719
GPRC5D Protein, Human, Recombinant (His & FLAG) is expressed in HEK293 mammalian cells with His and Flag tag. The predicted molecular weight is 32.83 kDa and the...
GPRC5D Protein-VLP, Human, Recombinant (GFP)
TMPY-06806
GPRC5D Protein, Human, Recombinant, Fluorescent is expressed in HEK293 mammalian cells. The predicted molecular weight is 65.81 kDa and the accession number is Q...
GPRC5D Protein-VLP, Mouse, Recombinant (Flag)
TMPY-06807
GPRC5D Protein, Mouse, Recombinant (Flag) is expressed in HEK293 mammalian cells with Flag tag. The predicted molecular weight is 35.8 kDa and the accession numb...
GLP1R Protein, Human, Recombinant (His & Avi)
TMPY-06864
Glucagon-like peptide (GLP)-1 receptor is encoded by GLP1R. GLP1R plays a critical role in mediating the biological actions of GLP1 in mammals and fish. The neur...
Frizzled 5 Protein, Human, Recombinant (His)
TMPY-01469
Frizzled 5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.6 kDa and the accession nu...
Renin Protein, Human, Recombinant (His)
TMPY-00908
Renin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.7 kDa and the accession number ...
TSHR Protein, Human, Recombinant (His)
TMPY-04853
Thyroid-stimulating hormone (TSH) is secreted by the pituitary gland and promotes thyroid growth and function, with increased TSH levels typically associated wit...
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TargetMol