G protein-coupled receptors (GPCRs) form a large group of evolutionarily related proteins that are cell surface receptors that detect molecules outside the cell and activate cellular responses. GPCRs are found only in eukaryotes, including yeast, and choanoflagellates. The ligands that bind and activate these receptors include light-sensitive compounds, odors, pheromones, hormones, and neurotransmitters.
GPCRs are involved in many diseases such as mental, metabolic including endocrinological disorders, immunological including viral infections, cardiovascular, inflammatory, senses disorders, and cancer. Therefore, GPCRs are an important drug target and approximately 34% of all Food and Drug Administration (FDA) approved drugs target 108 members of this family.
Cat No. | product name / Synonyms | Species | Expression System |
---|---|---|---|
TMPY-01365 | CD97 Protein, Human, Recombinant (His)
CD97 Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
CD97 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.6 kDa and the accession number i... | |||
TMPY-01683 | CD97 Protein, Human, Recombinant (hFc)
CD97 Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
CD97 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 68.2 kDa and the accession number i... | |||
TMPY-01797 | Frizzled 10 Protein, Mouse, Recombinant (hFc)
Frizzled 10 Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 Cells |
Frizzled 10 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43 kDa and the accession num... | |||
TMPY-01798 | Frizzled 10 Protein, Mouse, Recombinant (His)
Frizzled 10 Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 Cells |
Frizzled 10 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.4 kDa and the accession n... | |||
TMPY-02037 | TSC22D1 Protein, Mouse, Recombinant (His)
TSC22D1 Protein, Mouse, Recombinant (His)
|
Mouse | E. coli |
TSC22D1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 17.8 kDa and the accession nu... | |||
TMPY-02276 | GPR56 Protein, Human, Recombinant (His)
GPR56 Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
ADGRG1 (Adhesion G Protein-Coupled Receptor G1, also known as GPR56) is a Protein Coding gene. GPR56 is a member of an adhesion G protein-coupled receptor family... | |||
TMPY-02400 | TSC22D1 Protein, Human, Recombinant (His)
TSC22D1 Protein, Human, Recombinant (His)
|
Human | E. coli |
TSC22D1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 17.2 kDa and the accession nu... | |||
TMPY-02717 | GPR37 Protein, Human, Recombinant (His)
GPR37 Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
GPR37 (cathepsin Z) is an orphan receptor that belongs to the G-protein coupled receptor 1 family. G protein-coupled receptors are a large protein family compris... | |||
TMPY-02837 | GPR114 Protein, Human, Recombinant (hFc)
GPR114 Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
GPR114 belongs to the G-protein coupled receptor 2 family. Members of this family share a common molecular architecture which consists of seven transmembrane dom... | |||
TMPY-03293 | Frizzled 5 Protein, Mouse, Recombinant (hFc)
Frizzled 5 Protein, Mouse, Recombinant (hFc)
|
Mouse | CHO Cells |
Frizzled 5 Protein, Mouse, Recombinant (hFc) is expressed in CHO mammalian cells with hFc tag. The predicted molecular weight is 42.9 kDa and the accession numbe... | |||
TMPY-03310 | Frizzled 4 Protein, Rat, Recombinant (hFc)
Frizzled 4 Protein, Rat, Recombinant (hFc)
|
Rat | HEK293 Cells |
Familial exudative vitreoretinopathy (FEVR) is a hereditary blinding disorder that features defects in retinal vascular development. Mutations in FZD4 are known ... | |||
TMPY-03860 | Endothelin B Receptor Protein, Human, Recombinant (mFc)
Endothelin B Receptor Protein, Human, Recombinant (mFc)
|
Human | HEK293 Cells |
Endothelin B Receptor Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 34.4 kDa and the a... | |||
TMPY-04140 | Frizzled 10 Protein, Human, Recombinant (hFc)
Frizzled 10 Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
Frizzled 10 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.8 kDa and the accession n... | |||
TMPY-04147 | Frizzled 10 Protein, Human, Recombinant (His)
Frizzled 10 Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
Frizzled 10 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.5 kDa and the accession n... | |||
TMPY-04270 | GPR133 Protein, Human, Recombinant (His)
GPR133 Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
ADGRD1 (Adhesion G Protein-Coupled Receptor D1, also known as GPR133) is a Protein Coding gene. 4 alternatively spliced human isoforms have been reported. ADGRD1... | |||
TMPY-04271 | Frizzled 6 Protein, Human, Recombinant (His)
Frizzled 6 Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
Frizzled 6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.1 kDa and the accession nu... | |||
TMPY-04302 | Frizzled 4 Protein, Human, Recombinant (His)
Frizzled 4 Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
Familial exudative vitreoretinopathy (FEVR) is a hereditary blinding disorder that features defects in retinal vascular development. Mutations in FZD4 are known ... | |||
TMPY-04633 | Frizzled 2 Protein, Mouse, Recombinant (hFc)
Frizzled 2 Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 Cells |
FZD2 may be a tumor suppressor gene in salivary adenoid cystic carcinomas (SACCs) that inhibits cell growth and migration. OMOD2 is a rare skeletal dysplasia and... | |||
TMPY-05489 | Frizzled 5 Protein, Human, Recombinant (hFc)
Frizzled 5 Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
Frizzled 5 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.7 kDa and the accession nu... | |||
TMPY-05808 | Renin Protein, Human, Recombinant (R66K, His)
Renin Protein, Human, Recombinant (R66K, His)
|
Human | HEK293 Cells |
Renin Protein, Human, Recombinant (R66K, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.74 kDa and the accession ... |