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Fibroblast Growth Factor Receptors, FGFRs

The fibroblast growth factor receptors (FGFR) are receptors that bind to members of the fibroblast growth factor (FGF) family of proteins. The fibroblast growth factor receptors consist of an extracellular ligand domain composed of three immunoglobulin-like domains, a single transmembrane helix domain, and an intracellular domain with tyrosine kinase activity. The FGF/FGFR signalling pathway is involved in a variety of cancers.There are non-selective FGFR inhibitors that act on all of FGFR1-4 and other proteins, and some selective FGFR inhibitors for some/all of FGFR1-4. Selective FGFR inhibitors include AZD4547, BGJ398, JNJ42756493, and PD173074.

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Species
Cynomolgus (3)
Human (50)
Mouse (11)
Rat (2)
Rhesus (6)
Expression System
Baculovirus Insect Cells (3)
HEK293 Cells (68)
Tag
C-6xHis (1)
C-Avi (2)
C-His (24)
C-His-Avi (21)
C-hFc (17)
GST (3)
His (6)
hFc (3)
Cat No. product name / Synonyms Species Expression System
TMPY-01360 FGFRL1 Protein, Mouse, Recombinant (His)
FGFRL1 Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
Fibroblast growth factor receptor-like 1 (FGFRL1) also known as Fibroblast growth factor receptor 5 (FGFR5), is a member of the fibroblast growth factor receptor...
TMPY-01781 FGFR1 Protein, Mouse, Recombinant (His)
FGFR1 Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
FGFR1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.9 kDa and the accession number ...
TMPY-01782 FGFR1 Protein, Mouse, Recombinant (hFc)
FGFR1 Protein, Mouse, Recombinant (hFc)
Mouse HEK293 Cells
FGFR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66.5 kDa and the accession number ...
TMPY-02635 FGFR4 Protein, Rat, Recombinant (hFc)
FGFR4 Protein, Rat, Recombinant (hFc)
Rat HEK293 Cells
FGFR4 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66 kDa and the accession number is Q...
TMPY-02853 FGFR3 Protein, Cynomolgus, Recombinant (hFc)
FGFR3 Protein, Cynomolgus, Recombinant (hFc)
Cynomolgus HEK293 Cells
FGFR3 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.1 kDa and the accession nu...
TMPY-02862 FGFR4 Protein, Rat, Recombinant (His)
FGFR4 Protein, Rat, Recombinant (His)
Rat HEK293 Cells
FGFR4 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.3 kDa and the accession number is...
TMPY-03322 FGFR4 Protein, Rhesus, Recombinant (hFc)
FGFR4 Protein, Rhesus, Recombinant (hFc)
Rhesus HEK293 Cells
FGFR4 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.6 kDa and the accession number...
TMPY-03350 FGFR1 Protein, Rhesus, Recombinant (hFc)
FGFR1 Protein, Rhesus, Recombinant (hFc)
Rhesus HEK293 Cells
FGFR1 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.2 kDa and the accession number...
TMPY-03389 FGFR2 Protein, Mouse, Recombinant (His)
FGFR2 Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
FGFR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.5 kDa and the accession number ...
TMPY-03455 FGFR1OP Protein, Human, Recombinant (His & GST)
FGFR1OP Protein, Human, Recombinant (His & GST)
Human Baculovirus Insect Cells
FOP( fibroblast growth factor receptor 1 oncogene partner) is a largely hydrophilic protein postulated to be a leucine-rich protein family member. FOP contain...
TMPY-03683 FGFR4 Protein, Rhesus, Recombinant (His)
FGFR4 Protein, Rhesus, Recombinant (His)
Rhesus HEK293 Cells
FGFR4 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 61.8 kDa and the accession number...
TMPY-03926 FGFR1 Protein, Rhesus, Recombinant (His)
FGFR1 Protein, Rhesus, Recombinant (His)
Rhesus HEK293 Cells
FGFR1 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.6 kDa and the accession number...
TMPY-04200 FGFR3 Protein, Human, Recombinant (hFc)
FGFR3 Protein, Human, Recombinant (hFc)
Human HEK293 Cells
FGFR3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 64.9 kDa and the accession number ...
TMPY-04273 FGFR2 Protein, Human, Recombinant (aa 1-378, His)
FGFR2 Protein, Human, Recombinant (aa 1-378, His)
Human HEK293 Cells
FGFR2 Protein, Human, Recombinant (aa 1-378, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 41.1 kDa and the accessi...
TMPY-04371 FGFR1 Protein, Human, Recombinant (His & GST)
FGFR1 Protein, Human, Recombinant (His & GST)
Human Baculovirus Insect Cells
FGFR1 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 75 kDa and the acc...
TMPY-04390 FGFR2 Protein, Human, Recombinant (aa 400-821, His & GST)
FGFR2 Protein, Human, Recombinant (aa 400-821, His & GST)
Human Baculovirus Insect Cells
FGFR2 Protein, Human, Recombinant (aa 400-821, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 75.7 k...
TMPY-05761 FGFR1 Protein, Human, Recombinant (His), Biotinylated
FGFR1 Protein, Human, Recombinant (His), Biotinylated
Human HEK293 Cells
FGFR1 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the acces...
TMPY-05777 FGFR1 Protein, Human, Recombinant (hFc)
FGFR1 Protein, Human, Recombinant (hFc)
Human HEK293 Cells
FGFR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.15 kDa and the accession number...
TMPY-06033 FGFR1 Protein, Human, Recombinant (beta (IIIb), hFc)
FGFR1 Protein, Human, Recombinant (beta (IIIb), hFc)
Human HEK293 Cells
FGFR1 Protein, Human, Recombinant (beta (IIIb), hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56 kDa and the access...
TMPY-06035 FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc)
FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc)
Human HEK293 Cells
FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.7 kDa and the acc...
FGFRL1 Protein, Mouse, Recombinant (His)
TMPY-01360
Fibroblast growth factor receptor-like 1 (FGFRL1) also known as Fibroblast growth factor receptor 5 (FGFR5), is a member of the fibroblast growth factor receptor...
FGFR1 Protein, Mouse, Recombinant (His)
TMPY-01781
FGFR1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.9 kDa and the accession number ...
FGFR1 Protein, Mouse, Recombinant (hFc)
TMPY-01782
FGFR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66.5 kDa and the accession number ...
FGFR4 Protein, Rat, Recombinant (hFc)
TMPY-02635
FGFR4 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66 kDa and the accession number is Q...
FGFR3 Protein, Cynomolgus, Recombinant (hFc)
TMPY-02853
FGFR3 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.1 kDa and the accession nu...
FGFR4 Protein, Rat, Recombinant (His)
TMPY-02862
FGFR4 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.3 kDa and the accession number is...
FGFR4 Protein, Rhesus, Recombinant (hFc)
TMPY-03322
FGFR4 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.6 kDa and the accession number...
FGFR1 Protein, Rhesus, Recombinant (hFc)
TMPY-03350
FGFR1 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.2 kDa and the accession number...
FGFR2 Protein, Mouse, Recombinant (His)
TMPY-03389
FGFR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.5 kDa and the accession number ...
FGFR1OP Protein, Human, Recombinant (His & GST)
TMPY-03455
FOP( fibroblast growth factor receptor 1 oncogene partner) is a largely hydrophilic protein postulated to be a leucine-rich protein family member. FOP contain...
FGFR4 Protein, Rhesus, Recombinant (His)
TMPY-03683
FGFR4 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 61.8 kDa and the accession number...
FGFR1 Protein, Rhesus, Recombinant (His)
TMPY-03926
FGFR1 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.6 kDa and the accession number...
FGFR3 Protein, Human, Recombinant (hFc)
TMPY-04200
FGFR3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 64.9 kDa and the accession number ...
FGFR2 Protein, Human, Recombinant (aa 1-378, His)
TMPY-04273
FGFR2 Protein, Human, Recombinant (aa 1-378, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 41.1 kDa and the accessi...
FGFR1 Protein, Human, Recombinant (His & GST)
TMPY-04371
FGFR1 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 75 kDa and the acc...
FGFR2 Protein, Human, Recombinant (aa 400-821, His & GST)
TMPY-04390
FGFR2 Protein, Human, Recombinant (aa 400-821, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 75.7 k...
FGFR1 Protein, Human, Recombinant (His), Biotinylated
TMPY-05761
FGFR1 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the acces...
FGFR1 Protein, Human, Recombinant (hFc)
TMPY-05777
FGFR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.15 kDa and the accession number...
FGFR1 Protein, Human, Recombinant (beta (IIIb), hFc)
TMPY-06033
FGFR1 Protein, Human, Recombinant (beta (IIIb), hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56 kDa and the access...
FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc)
TMPY-06035
FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.7 kDa and the acc...
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