The fibroblast growth factor receptors (FGFR) are receptors that bind to members of the fibroblast growth factor (FGF) family of proteins. The fibroblast growth factor receptors consist of an extracellular ligand domain composed of three immunoglobulin-like domains, a single transmembrane helix domain, and an intracellular domain with tyrosine kinase activity. The FGF/FGFR signalling pathway is involved in a variety of cancers.There are non-selective FGFR inhibitors that act on all of FGFR1-4 and other proteins, and some selective FGFR inhibitors for some/all of FGFR1-4. Selective FGFR inhibitors include AZD4547, BGJ398, JNJ42756493, and PD173074.
Cat No. | product name / Synonyms | Species | Expression System |
---|---|---|---|
TMPY-01360 | FGFRL1 Protein, Mouse, Recombinant (His)
FGFRL1 Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 Cells |
Fibroblast growth factor receptor-like 1 (FGFRL1) also known as Fibroblast growth factor receptor 5 (FGFR5), is a member of the fibroblast growth factor receptor... | |||
TMPY-01781 | FGFR1 Protein, Mouse, Recombinant (His)
FGFR1 Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 Cells |
FGFR1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.9 kDa and the accession number ... | |||
TMPY-01782 | FGFR1 Protein, Mouse, Recombinant (hFc)
FGFR1 Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 Cells |
FGFR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66.5 kDa and the accession number ... | |||
TMPY-02635 | FGFR4 Protein, Rat, Recombinant (hFc)
FGFR4 Protein, Rat, Recombinant (hFc)
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Rat | HEK293 Cells |
FGFR4 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66 kDa and the accession number is Q... | |||
TMPY-02853 | FGFR3 Protein, Cynomolgus, Recombinant (hFc)
FGFR3 Protein, Cynomolgus, Recombinant (hFc)
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Cynomolgus | HEK293 Cells |
FGFR3 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.1 kDa and the accession nu... | |||
TMPY-02862 | FGFR4 Protein, Rat, Recombinant (His)
FGFR4 Protein, Rat, Recombinant (His)
|
Rat | HEK293 Cells |
FGFR4 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.3 kDa and the accession number is... | |||
TMPY-03322 | FGFR4 Protein, Rhesus, Recombinant (hFc)
FGFR4 Protein, Rhesus, Recombinant (hFc)
|
Rhesus | HEK293 Cells |
FGFR4 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.6 kDa and the accession number... | |||
TMPY-03350 | FGFR1 Protein, Rhesus, Recombinant (hFc)
FGFR1 Protein, Rhesus, Recombinant (hFc)
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Rhesus | HEK293 Cells |
FGFR1 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.2 kDa and the accession number... | |||
TMPY-03389 | FGFR2 Protein, Mouse, Recombinant (His)
FGFR2 Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 Cells |
FGFR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.5 kDa and the accession number ... | |||
TMPY-03455 | FGFR1OP Protein, Human, Recombinant (His & GST)
FGFR1OP Protein, Human, Recombinant (His & GST)
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Human | Baculovirus Insect Cells |
FOP( fibroblast growth factor receptor 1 oncogene partner) is a largely hydrophilic protein postulated to be a leucine-rich protein family member. FOP contain... | |||
TMPY-03683 | FGFR4 Protein, Rhesus, Recombinant (His)
FGFR4 Protein, Rhesus, Recombinant (His)
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Rhesus | HEK293 Cells |
FGFR4 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 61.8 kDa and the accession number... | |||
TMPY-03926 | FGFR1 Protein, Rhesus, Recombinant (His)
FGFR1 Protein, Rhesus, Recombinant (His)
|
Rhesus | HEK293 Cells |
FGFR1 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.6 kDa and the accession number... | |||
TMPY-04200 | FGFR3 Protein, Human, Recombinant (hFc)
FGFR3 Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
FGFR3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 64.9 kDa and the accession number ... | |||
TMPY-04273 | FGFR2 Protein, Human, Recombinant (aa 1-378, His)
FGFR2 Protein, Human, Recombinant (aa 1-378, His)
|
Human | HEK293 Cells |
FGFR2 Protein, Human, Recombinant (aa 1-378, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 41.1 kDa and the accessi... | |||
TMPY-04371 | FGFR1 Protein, Human, Recombinant (His & GST)
FGFR1 Protein, Human, Recombinant (His & GST)
|
Human | Baculovirus Insect Cells |
FGFR1 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 75 kDa and the acc... | |||
TMPY-04390 | FGFR2 Protein, Human, Recombinant (aa 400-821, His & GST)
FGFR2 Protein, Human, Recombinant (aa 400-821, His & GST)
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Human | Baculovirus Insect Cells |
FGFR2 Protein, Human, Recombinant (aa 400-821, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 75.7 k... | |||
TMPY-05761 | FGFR1 Protein, Human, Recombinant (His), Biotinylated
FGFR1 Protein, Human, Recombinant (His), Biotinylated
|
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the acces... | |||
TMPY-05777 | FGFR1 Protein, Human, Recombinant (hFc)
FGFR1 Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.15 kDa and the accession number... | |||
TMPY-06033 | FGFR1 Protein, Human, Recombinant (beta (IIIb), hFc)
FGFR1 Protein, Human, Recombinant (beta (IIIb), hFc)
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Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (beta (IIIb), hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56 kDa and the access... | |||
TMPY-06035 | FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc)
FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc)
|
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.7 kDa and the acc... |