The fibroblast growth factor receptors (FGFR) are receptors that bind to members of the fibroblast growth factor (FGF) family of proteins. The fibroblast growth factor receptors consist of an extracellular ligand domain composed of three immunoglobulin-like domains, a single transmembrane helix domain, and an intracellular domain with tyrosine kinase activity. The FGF/FGFR signalling pathway is involved in a variety of cancers.There are non-selective FGFR inhibitors that act on all of FGFR1-4 and other proteins, and some selective FGFR inhibitors for some/all of FGFR1-4. Selective FGFR inhibitors include AZD4547, BGJ398, JNJ42756493, and PD173074.
Cat No. | product name / Synonyms | Species | Expression System |
---|---|---|---|
TMPK-00395 | FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 Cells |
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weigh... | |||
TMPK-00396 | FGFR2 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR2 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 Cells |
FGFR2 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weigh... | |||
TMPK-00397 | FGFR2 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR2 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 Cells |
FGFR2 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight... | |||
TMPK-00398 | FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi)
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi)
|
Human | HEK293 Cells |
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi) is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 15.49 kDa and... | |||
TMPK-00399 | FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated
|
Human | HEK293 Cells |
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is... | |||
TMPK-00400 | FGFR2 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR2 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 Cells |
FGFR2 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight... | |||
TMPK-00401 | FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 Cells |
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, t... | |||
TMPK-00475 | FGFR2 beta (IIIb) Protein, Cynomolgus, Recombinant (His)
FGFR2 beta (IIIb) Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | HEK293 Cells |
FGFR2 beta (IIIb) Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 26.2 kDa and th... | |||
TMPK-00686 | FGFR3 alpha (IIIb) Protein, Mouse, Recombinant (His)
FGFR3 alpha (IIIb) Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 Cells |
FGFR3 alpha (IIIb) Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 37.09 kDa and the a... | |||
TMPK-00847 | FGFR2 beta (IIIb) Protein, Mouse, Recombinant (His)
FGFR2 beta (IIIb) Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 Cells |
FGFR2 beta (IIIb) Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 26.3 kDa and the acc... | |||
TMPK-01322 | FGFR4 Protein, Rhesus macaque, Recombinant (His)
FGFR4 Protein, Rhesus macaque, Recombinant (His)
|
Rhesus | HEK293 Cells |
FGFR4 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 39.66 kDa and the acces... | |||
TMPY-00257 | FGFR3 Protein, Cynomolgus, Rhesus, Recombinant (His)
FGFR3 Protein, Cynomolgus, Rhesus, Recombinant (His)
|
Cynomolgus,Rhesus | HEK293 Cells |
FGFR3 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.5 kDa and the acce... | |||
TMPY-00351 | FGFR2 Protein, Human, Recombinant (beta IIIc, His)
FGFR2 Protein, Human, Recombinant (beta IIIc, His)
|
Human | HEK293 Cells |
FGFR2 Protein, Human, Recombinant (beta IIIc, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.2 kDa and the access... | |||
TMPY-00389 | FGFR3 Protein, Human, Recombinant (alpha IIIb, hFc)
FGFR3 Protein, Human, Recombinant (alpha IIIb, hFc)
|
Human | HEK293 Cells |
FGFR3 Protein, Human, Recombinant (alpha IIIb, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.3 kDa and the acces... | |||
TMPY-00806 | FGFR4 Protein, Human, Recombinant (hFc)
FGFR4 Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
FGFR4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66 kDa and the accession number is... | |||
TMPY-00973 | FGFR3 Protein, Mouse, Recombinant (His & hFc)
FGFR3 Protein, Mouse, Recombinant (His & hFc)
|
Mouse | HEK293 Cells |
FGFR3 Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 66 kDa and the acces... | |||
TMPY-00974 | FGFR4 Protein, Mouse, Recombinant (His)
FGFR4 Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 Cells |
FGFR4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is... | |||
TMPY-01019 | FGFR4 Protein, Mouse, Recombinant (His & hFc)
FGFR4 Protein, Mouse, Recombinant (His & hFc)
|
Mouse | HEK293 Cells |
FGFR4 Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 67 kDa and the acces... | |||
TMPY-01208 | FGFR3 Protein, Mouse, Recombinant (His)
FGFR3 Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 Cells |
FGFR3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37 kDa and the accession number is... | |||
TMPY-01228 | FGFR2 Protein, Human, Recombinant (aa 1-377, His)
FGFR2 Protein, Human, Recombinant (aa 1-377, His)
|
Human | HEK293 Cells |
FGFR2 Protein, Human, Recombinant (aa 1-377, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 41 kDa and the accession... |