The fibroblast growth factor receptors (FGFR) are receptors that bind to members of the fibroblast growth factor (FGF) family of proteins. The fibroblast growth factor receptors consist of an extracellular ligand domain composed of three immunoglobulin-like domains, a single transmembrane helix domain, and an intracellular domain with tyrosine kinase activity. The FGF/FGFR signalling pathway is involved in a variety of cancers.There are non-selective FGFR inhibitors that act on all of FGFR1-4 and other proteins, and some selective FGFR inhibitors for some/all of FGFR1-4. Selective FGFR inhibitors include AZD4547, BGJ398, JNJ42756493, and PD173074.
Cat No. | product name / Synonyms | Species | Expression System |
---|---|---|---|
TMPY-06037 | FGFR4 Protein, Human, Recombinant (His), Biotinylated
FGFR4 Protein, Human, Recombinant (His), Biotinylated
|
Human | HEK293 Cells |
FGFR4 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the acces... | |||
TMPY-06321 | FGFR2 Protein, Human, Recombinant (alpha(IIIb), His & Avi), Biotinylated
FGFR2 Protein, Human, Recombinant (alpha(IIIb), His & Avi), Biotinylated
|
Human | HEK293 Cells |
FGFR2 Protein, Human, Recombinant (alpha(IIIb), His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular wei... | |||
TMPY-04165 | FGFR3 Protein, Human, Recombinant (His)
FGFR3 Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
FGFR3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.6 kDa and the accession number ... | |||
TMPY-00341 | FGFR3 Protein, Human, Recombinant (alpha IIIb, His)
FGFR3 Protein, Human, Recombinant (alpha IIIb, His)
|
Human | HEK293 Cells |
FGFR3 Protein, Human, Recombinant (alpha IIIb, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accessi... | |||
TMPY-06036 | FGFR1 Protein, Human, Recombinant (alpha (IIIb), His)
FGFR1 Protein, Human, Recombinant (alpha (IIIb), His)
|
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (alpha (IIIb), His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.5 kDa and the acc... | |||
TMPY-06034 | FGFR1 Protein, Human, Recombinant (beta (IIIb), His)
FGFR1 Protein, Human, Recombinant (beta (IIIb), His)
|
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (beta (IIIb), His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.8 kDa and the acce... | |||
TMPY-02112 | FGFR4 Protein, Human, Recombinant (His)
FGFR4 Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
FGFR4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is... | |||
TMPY-01011 | FGFR1 Protein, Human, Recombinant (His)
FGFR1 Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number is... | |||
TMPY-00423 | FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc)
FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc)
|
Human | HEK293 Cells |
FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66.3 kDa and the acces... | |||
TMPY-00972 | FGFR2 Protein, Human, Recombinant (His & hFc)
FGFR2 Protein, Human, Recombinant (His & hFc)
|
Human | HEK293 Cells |
FGFR2 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 67.6 kDa and the acc... | |||
TMPY-03357 | FGFR2 Protein, Mouse, Recombinant (hFc)
FGFR2 Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 Cells |
FGFR2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54.1 kDa and the accession number ... |