Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CJ-13,610 hydrochloride is an orally active nonredox-type inhibitor of 5-LOX and can be used in studies about the prevention of untoward pathophysiological effects of LTs.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 50.00 | |
5 mg | In stock | $ 98.00 | |
10 mg | In stock | $ 169.00 | |
25 mg | In stock | $ 373.00 | |
50 mg | In stock | $ 556.00 | |
100 mg | In stock | $ 783.00 | |
500 mg | In stock | $ 1,650.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 159.00 |
Description | CJ-13,610 hydrochloride is an orally active nonredox-type inhibitor of 5-LOX and can be used in studies about the prevention of untoward pathophysiological effects of LTs. |
In vitro | In intact human polymorphonuclear leukocytes (PMNL), challenged with the Ca(2+)-ionophore A23187, CJ-13,610 hydrochloride potently suppressed 5-LOX product formation with an IC50 of 70 nM. In transfected HeLa cells, CJ-13,610 hydrochloride only slightly discriminated between phosphorylatable wild-type 5-LOX and a 5-LOX mutant that lacks phosphorylation sites[2]. |
Molecular Weight | 429.96 |
Formula | C22H24ClN3O2S |
CAS No. | 179420-27-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45 mg/mL (104.66 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
CJ-13,610 hydrochloride 179420-27-0 Metabolism Lipoxygenase CJ 13,610 hydrochloride CJ13,610 hydrochloride CJ-13,610 Hydrochloride inhibitor inhibit