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alpha-Tocopherolquinone

Catalog No. T7050   CAS 7559-04-8
Synonyms: Metarene

During hypoxia in rats, levels of α-tocopherylquinon have been found to rise. alpha-Tocopherolquinone (Metarene) is reported to downregulate the respiratory activity of mitochondria. alpha-Tocopherolquinone has also displayed antioxidant activities after it is reduced to tocopherylhydroquinone.

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alpha-Tocopherolquinone Chemical Structure
alpha-Tocopherolquinone, CAS 7559-04-8
Pack Size Availability Price/USD Quantity
10 mg In stock $ 30.00
25 mg In stock $ 64.00
50 mg In stock $ 93.00
1 mL * 10 mM (in DMSO) In stock $ 30.00
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Purity: 99.89%
Purity: 98.13%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description During hypoxia in rats, levels of α-tocopherylquinon have been found to rise. alpha-Tocopherolquinone (Metarene) is reported to downregulate the respiratory activity of mitochondria. alpha-Tocopherolquinone has also displayed antioxidant activities after it is reduced to tocopherylhydroquinone.
Source
Synonyms Metarene
Molecular Weight 446.71
Formula C29H50O3
CAS No. 7559-04-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 50 mg/mL (111.93 mM)

TargetMolReferences and Literature

1. Siegel D, et al. The Reduction of α-Tocopherolquinone by Human NAD(P)H:Quinone Oxidoreductase: The Role of α-Tocopherolhydroquinone as a Cellular Antioxidant[J]. Molecular Pharmacology, 1997, 52(2):300-305. 2. Kanazawa H, et al. Determination of α-tocopherol and α-tocopherylquinone in rat tissues and plasma by high-performance liquid chromatography with electrochemical detection.[J]. Chemical & Pharmaceutical Bulletin, 2000, 48(10):1462-1466. 3. Lars Gille, et al. Redox-interaction of α-tocopheryl quinone with isolated mitochondrial cytochrome complex[J]. Biochemical Pharmacology, 2004, 68(2):373-381.

Related compound libraries

This product is contained In the following compound libraries:
Tobacco Monomer Library Drug Repurposing Compound Library Anti-Aging Compound Library Natural Product Library for HTS Covalent Natural Product Library Antioxidant Compound Library Anti-COVID-19 Compound Library Human Metabolite Library Bioactive Compounds Library Max Chinese Pharmacopoeia Natural Product Library

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Keywords

alpha-Tocopherolquinone 7559-04-8 oxidation-reduction Antioxidant Phaeodactylum tricornutum inhibit vitamin K α-Tocopherylquinone alpha Tocopherolquinone Metarene Inhibitor α-Tocopherolquinone quinone a-Tocopherolquinone alphaTocopherolquinone inhibitor

 

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