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alpha-Tocopherolquinone

Catalog No. T7050 CAS 7559-04-8

Synonyms: Metarene

During hypoxia in rats, levels of α-tocopherylquinon have been found to rise. It is reported to downregulate the respiratory activity of mitochondria. It has also displayed Antioxidant activities after it is reduced to tocopherylhydroquinone.

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alpha-Tocopherolquinone, CAS 7559-04-8

Pack Size	Availability	Price/USD
10 mg	In stock	$ 30.00
25 mg	In stock	$ 64.00
50 mg	In stock	$ 93.00
1 mL * 10 mM (in DMSO)	In stock	$ 34.00

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Purity: 99.89%

Purity: 98.13%

Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	During hypoxia in rats, levels of α-tocopherylquinon have been found to rise. It is reported to downregulate the respiratory activity of mitochondria. It has also displayed antioxidant activities after it is reduced to tocopherylhydroquinone.
Source	Natural Products > Lamiaceae > Isodon

Synonyms	Metarene
Molecular Weight	446.71
Formula	C29H50O3
CAS No.	7559-04-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 2 years

Solubility Information

DMSO: 50 mg/mL (111.93 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Siegel D, et al. The Reduction of α-Tocopherolquinone by Human NAD(P)H:Quinone Oxidoreductase: The Role of α-Tocopherolhydroquinone as a Cellular Antioxidant[J]. Molecular Pharmacology, 1997, 52(2):300-305. 2. Kanazawa H, et al. Determination of α-tocopherol and α-tocopherylquinone in rat tissues and plasma by high-performance liquid chromatography with electrochemical detection.[J]. Chemical & Pharmaceutical Bulletin, 2000, 48(10):1462-1466. 3. Lars Gille, et al. Redox-interaction of α-tocopheryl quinone with isolated mitochondrial cytochrome complex[J]. Biochemical Pharmacology, 2004, 68(2):373-381.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Aging Compound Library Human Endogenous Metabolite Compound Library Plus Anti-COVID-19 Compound Library The Yao nationality medicine Library Clinical Compound Library Mitochondria-Targeted Compound Library Anti-Fibrosis Compound Library Traditional Chinese Medicine Monomer Library Bioactive Compounds Library Max Drug Repurposing Compound Library

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Keywords

alpha-Tocopherolquinone 7559-04-8 oxidation-reduction Antioxidant Phaeodactylum tricornutum inhibit vitamin K α-Tocopherylquinone alpha Tocopherolquinone Metarene Inhibitor quinone alphaTocopherolquinone inhibitor

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