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Zileuton

Catalog No. T0477 CAS 111406-87-2

Synonyms: Abbott 64077, A 64077

Zileuton is a synthetic derivative of hydroxyurea with antiasthmatic properties. The leukotriene inhibitor zileuton blocks 5-lipoxygenase, which catalyzes the formation of leukotrienes from arachidonic acid; causes bronchodilation; decreases bronchial mucous secretion and edema; and may prevent or decrease the symptoms of asthma.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Zileuton, CAS 111406-87-2

Pack Size	Availability	Price/USD
10 mg	In stock	50.00
25 mg	In stock	71.00
50 mg	In stock	117.00
100 mg	In stock	185.00
200 mg	In stock	333.00
1 mL * 10 mM (in DMSO)	In stock	50.00

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Purity 99.56%

HNMR HPLC COA

Purity 99.43%

HNMR HPLC COA

Datasheet SDS

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Zileuton is a synthetic derivative of hydroxyurea with antiasthmatic properties. The leukotriene inhibitor zileuton blocks 5-lipoxygenase, which catalyzes the formation of leukotrienes from arachidonic acid; causes bronchodilation; decreases bronchial mucous secretion and edema; and may prevent or decrease the symptoms of asthma.
Targets&IC50	5-Lipoxygenase , COX-1

Synonyms	Abbott 64077 , A 64077
Purity	99.56%
Molecular Weight	236.29
Formula	C11H12N2O2S
CAS No.	111406-87-2

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 6 months

Solubility Information

DMSO: 23.6 mg/mL (100 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

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Related compound libraries

This product is contained In the following compound libraries：

Approved Drug Library Bioactive Compound Library Inhibitor Library Anti-Cancer Compound Library Clinical Compound Library Anti-Infection Compound Library Apoptosis Compound Library Neuronal Signaling Compound Library FDA-Approved Drug Library Immunology/Inflammation Compound Library Bioactive Lipid Compound Library Anti-Cancer Approved Drug Library Anti-Cancer Clinical Compound Library Anti-Metabolism Disease Compound Library Anti-Cancer Metabolism Compound Library Anti-Obesity Compound Library Anti-Aging Compound Library Anti-Cancer Drug Library Drug Repurposing Compound Library Ferroptosis Compound Library Drug-induced Liver Injury (DILI) Compound Library Nonsteroidal Anti-Inflammatory Compound Library FDA-Approved & Pharmacopeia Drug Library Lipid Metabolism Compound Library

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Related compounds with same targets

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.