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VU0357017 hydrochloride

Catalog No. T3619 CAS 1135242-13-5

Synonyms: ML071 hydrochloride, CID-25010775, VU 0357017 hydrochloride

VU0357017 hydrochloride (ML071 hydrochloride) is highly selective M1 agonists act at an allosteric site to activate the receptor (EC50: 477 ± 172 nM; Pec50: 6.37 ± 0.15).

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VU0357017 hydrochloride Chemical Structure

VU0357017 hydrochloride, CAS 1135242-13-5

Pack Size	Availability	Price/USD
1 mg	In stock	$ 31.00
2 mg	In stock	$ 41.00
5 mg	In stock	$ 67.00
10 mg	In stock	$ 108.00
25 mg	In stock	$ 212.00
50 mg	In stock	$ 315.00
100 mg	In stock	$ 469.00
500 mg	In stock	$ 987.00
1 mL * 10 mM (in DMSO)	In stock	$ 68.00

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Purity: 99.9%

Purity: 99.13%

Purity: 99%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	VU0357017 hydrochloride (ML071 hydrochloride) is highly selective M1 agonists act at an allosteric site to activate the receptor (EC50: 477 ± 172 nM; Pec50: 6.37 ± 0.15).
Targets&IC50	M1:477 ± 172 nM (EC50)

Synonyms	ML071 hydrochloride, CID-25010775, VU 0357017 hydrochloride
Molecular Weight	369.89
Formula	C18H28ClN3O3
CAS No.	1135242-13-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 33 mg/mL

References and Literature

1. Digby GJ, et al. ACS Chem Neurosci. 2012 Dec 19;3(12):1025-36. 2. Lebois EP, et al. ACS Chem Neurosci. 2010;1(2):104-121. 3. Digby GJ, et al. J Neurosci. 2012 Jun 20;32(25):8532-44. 4. Sheffler DJ. et al.Bioorg Med Chem Lett. 2013 Jan 1;23(1):223-7.

Related compound libraries

This product is contained In the following compound libraries：

Membrane Protein-targeted Compound Library Anti-Neurodegenerative Disease Compound Library Neurotransmitter Receptor Compound Library Anti-Parkinson's Disease Compound Library Target-Focused Phenotypic Screening Library CNS-Penetrant Compound Library Bioactive Compound Library Neuronal Signaling Compound Library NO PAINS Compound Library Bioactive Compounds Library Max

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Related compounds with same targets

Guvacoline hydrochloride Donepezil Hydrochloride Dipivefrin hydrochloride Benzetimide hydrochloride Bethanechol chloride GNF-7 Isopropamide Iodide SCH 57790

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

VU0357017 hydrochloride 1135242-13-5 Neuroscience AChR VU0357017 Hydrochloride inhibit ML071 hydrochloride VU 0357017 VU0357017 muscarinic CID-25010775 VU 0357017 hydrochloride acetylcholine,Alzheimer’s CID 25010775 Inhibitor ML 071 Hydrochloride Muscarinic acetylcholine receptor VU 0357017 Hydrochloride schizophrenia ML071 Hydrochloride ML-071 Hydrochloride VU-0357017 mAChR VU-0357017 Hydrochloride VU-0357017 hydrochloride CID25010775 inhibitor

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