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Thiamine disulfide

Catalog No. T20062 CAS 67-16-3

Synonyms: TDS, Daiomin, Algoneurina

Thiamine disulfide (Algoneurina) , also known as thiamin or vitamin B1, is a vitamin found in food and manufactured as a dietary supplement and medication. Thiamine also acts as a cofactor for many centrally metabolizing enzymes.

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Thiamine disulfide, CAS 67-16-3

Pack Size	Availability	Price/USD	Quantity
500 mg	In stock	$ 41.00
1 mL * 10 mM (in DMSO)	In stock	$ 45.00

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Purity: 99.18%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	TDS, Daiomin, Algoneurina
Molecular Weight	562.71
Formula	C24H34N8O4S2
CAS No.	67-16-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 250 mg/mL (444.28 mM), Sonication is recommended.

References and Literature

1. Xiao D, Meng FH, Dai W, Yong Z, Liu JQ, Zhou XB, Li S. Design, Synthesis and Biological Evaluation of Brain-Targeted Thiamine Disulfide Prodrugs of Ampakine Compound LCX001. Molecules. 2016 Apr 14;21(4):488. doi: 10.3390/molecules21040488. PubMed PMID: 27089316. 2. Volvert ML, Seyen S, Piette M, Evrard B, Gangolf M, Plumier JC, Bettendorff L. Benfotiamine, a synthetic S-acyl thiamine derivative, has different mechanisms of action and a different pharmacological profile than lipid-soluble thiamine disulfide derivatives. BMC Pharmacol. 2008 Jun 12;8:10. doi: 10.1186/1471-2210-8-10. PubMed PMID: 18549472; PubMed Central PMCID: PMC2435522. 3. Parkhomenko IuM, Stepuro II, Donchenko GV, Stepuro VI. [Oxidized derivatives of thiamine: formation, properties, biological role]. Ukr Biokhim Zh (1999). 2012 Nov-Dec;84(6):5-24. Review. Russian. PubMed PMID: 23387265. 4. Stepuro II, Oparin AY, Stsiapura VI, Maskevich SA, Titov VY. Oxidation of thiamine on reaction with nitrogen dioxide generated by ferric myoglobin and hemoglobin in the presence of nitrite and hydrogen peroxide. Biochemistry (Mosc). 2012 Jan;77(1):41-55. doi: 10.1134/S0006297912010051. PubMed PMID: 22339632.

Related compound libraries

This product is contained In the following compound libraries：

Drug Repurposing Compound Library Bioactive Compounds Library Max Anti-Viral Compound Library Bioactive Compound Library Approved Drug Library Covalent Inhibitor Library Human Metabolite Library FDA-Approved & Pharmacopeia Drug Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Thiamine disulfide 67-16-3 Metabolism Microbiology/Virology Proteases/Proteasome Endogenous Metabolite HIV Protease dimer Inhibitor AIDS inhibit vitamin-B1 HIV-1 TDS Daiomin Thiamine Disulfide Algoneurina Human immunodeficiency virus Thiamine HIV oxidized inhibitor

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