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TargetMol | Compound Library

Anti-Fibrosis Compound Library

Catalog No. L9810

Fibrosis, also known as fibrotic scarring, is a pathological wound healing in which connective tissue replaces normal parenchymal tissue to the extent that it goes unchecked, leading to considerable tissue remodeling and the formation of permanent scar tissue. If highly progressive, the fibrotic process eventually leads to organ malfunction and death. Fibrosis affects nearly every tissue in the body, such as lung, liver, kidney, bone marrow, etc. Fibrosis is the final, common pathological outcome of many chronic inflammatory diseases, including scleroderma, rheumatoid arthritis, Crohn's disease, ulcerative colitis, myelofibrosis and systemic lupus erythematosus.

TargetMol's Anti-Fibrosis Compound Library collects 1800 potential anti-fibrosis compounds, including inhibitors to TGF-beta, TNF-alpha, MMP, etc., antioxidants, anti-inflammatory compounds, etc. It is a powerful tool for research in fibrosis and related drug development.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L9810

Anti-Fibrosis Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

Product features Product features

  • A unique collection of 1800 potential anti-fibrosis compounds, can be used in HTS and HCS;
  • Targets include TGFβ、TNFα、MMP、EGFR、NADPH-oxidase, etc.
  • Some compounds are in the market (FDA-approved);
  • Detailed compound information with structure, target, IC50, and biological activity description;
  • NMR and HPLC/LCMS validated to ensure high purity and quality.

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Apoptosis
Autophagy
NF-κB
PI3K
Reactive Oxygen Species
COX
VEGFR
Ras
Endogenous Metabolite
p38 MAPK
Antibacterial
PDGFR
Akt
MMP
ERK
Antioxidant
mTOR
Wnt/beta-catenin
AMPK
TNF
Raf
TGF-beta/Smad
GSK-3
c-Kit
CDK
JNK
FGFR
FLT
Parasite
MEK
IκB/IKK
Src
Caspase
DNA-PK
MAPK
IL Receptor
Antibiotic
NO Synthase
EGFR
S6 Kinase
CFTR
Ferroptosis
STAT
Interleukin
ATM/ATR
ALK
KRas
Mitophagy
Antifungal
RIP kinase
DNA/RNA Synthesis
HIV Protease
JAK
Influenza Virus
Bcl-2 Family
NOD
Cytochromes P450
Calcium Channel
Bcr-Abl
Hedgehog/Smoothened
PPAR
Nrf2
Aurora Kinase
PDK
c-Met/HGFR
NOD-like Receptor (NLR)
PKC
Lipoxygenase
IRAK
c-RET
ROS
Mitochondrial Metabolism
HIF/HIF Prolyl-Hydroxylase
Casein Kinase
Virus Protease
PKA
NOS
PDE
c-Fms
Potassium Channel
Rho
Dehydrogenase
IGF-1R
Tyrosine Kinases
Cholinesterase (ChE)
ROCK
Beta Amyloid
HSV
Phosphatase
Prostaglandin Receptor
Tyrosinase
MLK
PI4K
FAK
PARP
Topoisomerase
P-gp
Trk receptor
Drug Metabolite
PGE Synthase
GABA Receptor
Sodium Channel
HDAC
Tie-2
Glucosidase
Smo
Epigenetic Reader Domain
SARS-CoV
AChR
PTEN
TLR
p53
Syk
LPL Receptor
NADPH
TRP/TRPV Channel
Adrenergic Receptor
Anti-infection
ATPase
Proteasome
Glutathione Peroxidase
Serine Protease
Chk
Antifection
BACE
Antiviral
transporter
Monoamine Oxidase
E1/E2/E3 Enzyme
Integrin
Estrogen Receptor/ERR
HSP
Phospholipase
Chloride channel
HCV Protease
MNK
Estrogen/progestogen Receptor
UGT
ASK
Microtubule Associated
GPCR
Adenosine Receptor
c-Myc
Ephrin Receptor
MDM-2/p53
ROS Kinase
Transferase
RANKL/RANK
LPA Receptor
5-HT Receptor
Carbonic Anhydrase
IAP
Porcupine
ribosome
HER
Reductase
RAAS
TOPK
CSF-1R
SIK
Ligand for E3 Ligase
TAM Receptor
Opioid Receptor
OXPHOS
Free radical scavengers
Gamma-secretase
Angiotensin-converting Enzyme (ACE)
S1P Receptor
MRP
GTPase
Histone Acetyltransferase
HIF
Necroptosis
Molecular Glues
Lipid
SGK
HBV
CCR
Beta-Secretase
Serine/threonin kinase
Leukotriene Receptor
FXR
Aryl Hydrocarbon Receptor
LDL
LRRK2
Pyroptosis
Retinoid Receptor
Cannabinoid Receptor
NADPH-oxidase
Immunology/Inflammation related
KLF
PLK
Histone Methyltransferase
PYK2
Survivin
Aminopeptidase
Mdm2
DYRK
Liver X Receptor
MAO
PAK
PAI-1
MELK
Gap Junction Protein
PD-1/PD-L1
Glucocorticoid Receptor
CaMK
SGLT
AhR
LTR
PERK
ATP Citrate Lyase
Sirtuin
Hippo pathway
Histamine Receptor
Myosin
DNA Alkylation
Proton pump
Cysteine Protease
Prolyl Endopeptidase (PREP)
IRE1
DNA gyrase
FKBP
BTK
FOXO3
IKZF
Adenylyl Cyclase
Dopamine Receptor
P2X Receptor
Fatty Acid Synthase
Somatostatin
PAD
Indoleamine 2,3-Dioxygenase (IDO)
Androgen Receptor
BCRP
Methionine Adenosyltransferase (MAT)
Cuproptosis
Discoidin Domain Receptor (DDR)
GSNOR
Y Box Binding Protein 1
Arginase
gp120/CD4
Photosensitizer
cAMP
AIM2
GST
Reverse Transcriptase
Aromatase
Platelet aggregation
YAP
IFNAR
Hck
IDO
Na-K-Cl cotransporter
Stearoyl-CoA Desaturase (SCD)
ACK1
BMI-1
Thrombin
PROTACs
CD38
Histone Demethylase
N-Acetylglucosaminyltransferase
iGluR
ABC Transporter
Anion Exchanger
FAAH
GluR
DNA
cGAS
CRISPR/Cas9
Hydroxylase
NPC1L1
DHFR
Cholecystokinin Receptor
AAK1
Glutathione reductase
Acyltransferase
Decarboxylase
Adenosine Deaminase
Monocarboxylate transporter
RAR/RXR
MyD88
Amylase
Guanylate cyclase
STING
GPX
PKM
ROR
Dynamin
Galectin
Cell Cycle Arrest
Haspin Kinase
DUB
GPCR19
RSV
ADC Cytotoxin

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