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TargetMol | Compound Library

Anti-Fibrosis Compound Library

Catalog No. L9810

Fibrosis, also known as fibrotic scarring, is a pathological wound healing in which connective tissue replaces normal parenchymal tissue to the extent that it goes unchecked, leading to considerable tissue remodeling and the formation of permanent scar tissue. If highly progressive, the fibrotic process eventually leads to organ malfunction and death. Fibrosis affects nearly every tissue in the body, such as lung, liver, kidney, bone marrow, etc. Fibrosis is the final, common pathological outcome of many chronic inflammatory diseases, including scleroderma, rheumatoid arthritis, Crohn's disease, ulcerative colitis, myelofibrosis and systemic lupus erythematosus.

TargetMol's Anti-Fibrosis Compound Library collects 1800 potential anti-fibrosis compounds, including inhibitors to TGF-beta, TNF-alpha, MMP, etc., antioxidants, anti-inflammatory compounds, etc. It is a powerful tool for research in fibrosis and related drug development.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L9810

Anti-Fibrosis Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

Product features Product features

  • A unique collection of 1800 potential anti-fibrosis compounds, can be used in HTS and HCS;
  • Targets include TGFβ、TNFα、MMP、EGFR、NADPH-oxidase, etc.
  • Some compounds are in the market (FDA-approved);
  • Detailed compound information with structure, target, IC50, and biological activity description;
  • NMR and HPLC/LCMS validated to ensure high purity and quality.

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Apoptosis
Autophagy
NF-κB
PI3K
Reactive Oxygen Species
COX
VEGFR
PDGFR
Endogenous Metabolite
p38 MAPK
MMP
Antioxidant
mTOR
Akt
ERK
AMPK
Wnt/beta-catenin
Antibacterial
TNF
Raf
TGF-beta/Smad
GSK-3
c-Kit
CDK
JNK
FGFR
Ras
MEK
FLT
IκB/IKK
Src
MAPK
IL Receptor
DNA-PK
Parasite
EGFR
CFTR
S6 Kinase
Antibiotic
ALK
STAT
ATM/ATR
Caspase
Ferroptosis
NO Synthase
RIP kinase
JAK
Mitophagy
HIV Protease
NOD
Calcium Channel
Antifungal
Influenza Virus
Hedgehog/Smoothened
Bcr-Abl
PDK
Cytochromes P450
PPAR
Aurora Kinase
PKC
c-Met/HGFR
DNA/RNA Synthesis
c-RET
Lipoxygenase
IRAK
ROS
Interleukin
Nrf2
Mitochondrial Metabolism
Bcl-2 Family
Rho
PDE
Potassium Channel
NOD-like Receptor (NLR)
PKA
NOS
IGF-1R
Casein Kinase
Tyrosine Kinases
c-Fms
Virus Protease
Dehydrogenase
Topoisomerase
Tyrosinase
ROCK
MLK
Beta Amyloid
Prostaglandin Receptor
Kras
HIF/HIF Prolyl-Hydroxylase
Cholinesterase (ChE)
PI4K
Trk receptor
p53
HDAC
Syk
P-gp
HSV
FAK
TLR
AChR
PGE Synthase
Adrenergic Receptor
Chk
Sodium Channel
Glutathione Peroxidase
Smo
NADPH
Serine Protease
TRP/TRPV Channel
Drug Metabolite
Antiviral
HCV Protease
Integrin
GABA Receptor
Epigenetic Reader Domain
PTEN
MNK
ATPase
Glucosidase
BACE
Chloride channel
E1/E2/E3 Enzyme
Phosphatase
Proteasome
TAM Receptor
Adenosine Receptor
S1P Receptor
Free radical scavengers
HSP
transporter
RAAS
ASK
Estrogen/progestogen Receptor
SARS-CoV
CSF-1R
Tie-2
Porcupine
Ligand for E3 Ligase
GPCR
TOPK
Carbonic Anhydrase
Anti-infection
Phospholipase
5-HT Receptor
LPA Receptor
HER
Transferase
PARP
SIK
Ephrin Receptor
Monoamine Oxidase
Estrogen Receptor/ERR
Opioid Receptor
ribosome
NADPH-oxidase
PLK
Reductase
LPL Receptor
LDL
c-Myc
IAP
MRP
HIF
Serine/threonin kinase
Retinoid Receptor
Microtubule Associated
GTPase
Immunology/Inflammation related
LRRK2
SGK
CCR
HBV
KLF
Molecular Glues
Aryl Hydrocarbon Receptor
Glucocorticoid Receptor
IRE1
Mdm2
Gamma-secretase
Histamine Receptor
Cysteine Protease
MELK
Leukotriene Receptor
Cannabinoid Receptor
PAI-1
DNA Alkylation
Sirtuin
Aminopeptidase
Antifection
CaMK
Proton pump
FXR
RANKL/RANK
DNA gyrase
UGT
AhR
LTR
Lipid
MAO
Beta-Secretase
Gap Junction Protein
FOXO3
BTK
Somatostatin
GSNOR
DUB
Decarboxylase
Aromatase
DYRK
PYK2
Glutathione reductase
BMI-1
Hippo pathway
DHFR
Platelet aggregation
Adenosine Deaminase
cGAS
AAK1
Amylase
Histone Demethylase
YAP
MyD88
PKM
RSV
Pyroptosis
RAR/RXR
BCRP
Cholecystokinin Receptor
Haspin Kinase
ROR
Indoleamine 2,3-Dioxygenase (IDO)
N-Acetylglucosaminyltransferase
ACK1
Methionine Adenosyltransferase (MAT)
Discoidin Domain Receptor (DDR)
P2X Receptor
SGLT
NPC1L1
Anion Exchanger
ATP Citrate Lyase
Guanylate cyclase
GluR
Monocarboxylate transporter
CRISPR/Cas9
FAAH
DNA
Dopamine Receptor
Liver X Receptor
iGluR
OXPHOS
Hydroxylase
Histone Acetyltransferase
gp120/CD4
cAMP
Cell Cycle Arrest
Histone Methyltransferase
GPX
Adenylyl Cyclase
Galectin
Thrombin
Myosin
STING
PD-1/PD-L1
Dynamin
Arginase
PERK
GST
Necroptosis
Reverse Transcriptase
IFNAR
Acyltransferase
Fatty Acid Synthase
PAD
PAK
ABC Transporter
Hck
PROTACs
ADC Cytotoxin

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