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TargetMol | Compound Library

Anti-Fibrosis Compound Library

Catalog No. L9810

Fibrosis, also known as fibrotic scarring, is a pathological wound healing in which connective tissue replaces normal parenchymal tissue to the extent that it goes unchecked, leading to considerable tissue remodeling and the formation of permanent scar tissue. If highly progressive, the fibrotic process eventually leads to organ malfunction and death. Fibrosis affects nearly every tissue in the body, such as lung, liver, kidney, bone marrow, etc. Fibrosis is the final, common pathological outcome of many chronic inflammatory diseases, including scleroderma, rheumatoid arthritis, Crohn's disease, ulcerative colitis, myelofibrosis and systemic lupus erythematosus.

TargetMol's Anti-Fibrosis Compound Library collects 1800 potential anti-fibrosis compounds, including inhibitors to TGF-beta, TNF-alpha, MMP, etc., antioxidants, anti-inflammatory compounds, etc. It is a powerful tool for research in fibrosis and related drug development.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L9810

Anti-Fibrosis Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

Product features Product features

  • A unique collection of 1800 potential anti-fibrosis compounds, can be used in HTS and HCS;
  • Targets include TGFβ、TNFα、MMP、EGFR、NADPH-oxidase, etc.
  • Some compounds are in the market (FDA-approved);
  • Detailed compound information with structure, target, IC50, and biological activity description;
  • NMR and HPLC/LCMS validated to ensure high purity and quality.

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Apoptosis
Autophagy
NF-κB
PI3K
ROS
Reactive Oxygen Species
COX
Endogenous Metabolite
VEGFR
Ras
p38 MAPK
Antibacterial
ERK
Akt
PDGFR
MMP
mTOR
Wnt/beta-catenin
Antioxidant
TNF
AMPK
TGF-beta/Smad
Raf
GSK-3
JNK
c-Kit
CDK
FGFR
Parasite
MEK
FLT
IκB/IKK
Interleukin
NO Synthase
Caspase
Src
MAPK
DNA/RNA Synthesis
DNA-PK
Antibiotic
STAT
IL Receptor
EGFR
CFTR
S6 Kinase
Ferroptosis
HIV Protease
ATM/ATR
Kras
ALK
Mitophagy
Calcium Channel
Antifungal
PPAR
Bcl-2 Family
RIP kinase
Influenza Virus
JAK
Nrf2
NOD
Cytochromes P450
Bcr-Abl
Hedgehog/Smoothened
PDK
NOD-like Receptor (NLR)
c-Met/HGFR
PKC
Aurora Kinase
Lipoxygenase
IRAK
c-RET
Mitochondrial Metabolism
Virus Protease
HIF/HIF Prolyl-Hydroxylase
PDE
IGF-1R
Casein Kinase
PKA
Potassium Channel
Beta Amyloid
c-Fms
NOS
HSV
Rho
Dehydrogenase
SARS-CoV
Phosphatase
Prostaglandin Receptor
Tyrosine Kinases
Cholinesterase (ChE)
FAK
P-gp
Tyrosinase
MLK
ROCK
PI4K
Topoisomerase
TLR
PARP
Sodium Channel
Drug Metabolite
AChR
Trk receptor
HDAC
GABA Receptor
Anti-infection
PGE Synthase
Tie-2
Glucosidase
Smo
Epigenetic Reader Domain
HSP
Syk
PTEN
p53
ATPase
NADPH
TRP/TRPV Channel
Adrenergic Receptor
LPL Receptor
Proteasome
Integrin
Estrogen Receptor/ERR
Serine Protease
Chk
Glutathione Peroxidase
PERK
E1/E2/E3 Enzyme
Adenosine Receptor
c-Myc
MDM-2/p53
BACE
RANKL/RANK
CaMK
Antiviral
transporter
Monoamine Oxidase
Antifection
Reductase
Phospholipase
Gamma-secretase
Angiotensin-converting Enzyme (ACE)
MNK
Chloride channel
HCV Protease
Carbonic Anhydrase
IAP
glycosidase
Porcupine
ribosome
HER
GPCR
Ephrin Receptor
ROS Kinase
PD-1/PD-L1
Transferase
Necroptosis
LPA Receptor
5-HT Receptor
Estrogen/progestogen Receptor
UGT
ASK
Microtubule Associated
RAAS
TOPK
CSF-1R
SIK
Ligand for E3 Ligase
TAM Receptor
Immunology/Inflammation related
PLK
S1P Receptor
Serine/threonin kinase
Opioid Receptor
OXPHOS
Free radical scavengers
Pyroptosis
HBV
CCR
GTPase
Histone Acetyltransferase
HIF
Molecular Glues
Lipid
SGK
MRP
Survivin
Aminopeptidase
Beta-Secretase
KLF
Cysteine Protease
Leukotriene Receptor
FXR
Aryl Hydrocarbon Receptor
LDL
LRRK2
Retinoid Receptor
Cannabinoid Receptor
NADPH-oxidase
LTR
ATP Citrate Lyase
Sirtuin
Hippo pathway
Mdm2
DYRK
Liver X Receptor
MAO
PAK
PAI-1
MELK
Gap Junction Protein
Glucocorticoid Receptor
SGLT
AhR
Histone Methyltransferase
PYK2
Fatty Acid Synthase
Histamine Receptor
Myosin
DNA Alkylation
Proton pump
MyD88
Prolyl Endopeptidase (PREP)
IRE1
DNA gyrase
FKBP
BTK
FOXO3
IKZF
PROTACs
CD38
Histone Demethylase
N-Acetylglucosaminyltransferase
iGluR
ABC Transporter
Anion Exchanger
FAAH
GluR
DNA
CD74
cGAS
CRISPR/Cas9
Hydroxylase
GSNOR
Y Box Binding Protein 1
Arginase
gp120/CD4
Photosensitizer
cAMP
AIM2
GST
Reverse Transcriptase
Aromatase
Platelet aggregation
YAP
IFNAR
Hck
IDO
Na-K-Cl cotransporter
Stearoyl-CoA Desaturase (SCD)
ACK1
BMI-1
Thrombin
Adenylyl Cyclase
Dopamine Receptor
P2X Receptor
Somatostatin
PAD
Indoleamine 2,3-Dioxygenase (IDO)
Androgen Receptor
BCRP
Methionine Adenosyltransferase (MAT)
Cuproptosis
Discoidin Domain Receptor (DDR)
Kinesin
NPC1L1
DHFR
Cholecystokinin Receptor
AAK1
Glutathione reductase
Acyltransferase
Decarboxylase
Adenosine Deaminase
ROR
Dynamin
Galectin
Cell Cycle Arrest
Haspin Kinase
DUB
GPCR19
RSV
Tight Junction Protein
Monocarboxylate transporter
RAR/RXR
Amylase
Guanylate cyclase
CXCR
STING
GPX
PKM
ADC Cytotoxin

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