Powder: -20°C for 3 years | In solvent: -80°C for 2 years
Sprengerinin C exerts anti-tumorigenic effects in hepatocellular carcinoma via inhibition of proliferation and Angiogenesis and induction of Apoptosis, it can strongly suppress tumor Angiogenesis in human umbilical vein endothelial cells, it blocks vascular endothelial growth factor receptor 2-dependent phosphoinositide 3-kinase/Akt/mTOR/matrix metalloproteinase and p38 MAPK/matrix metalloproteinase pathways,two major pathways for tumor Angiogenesis.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | Inquiry | $ 660.00 | |
1 mL * 10 mM (in DMSO) | Inquiry | $ 1,000.00 |
Description | Sprengerinin C exerts anti-tumorigenic effects in hepatocellular carcinoma via inhibition of proliferation and angiogenesis and induction of apoptosis, it can strongly suppress tumor angiogenesis in human umbilical vein endothelial cells, it blocks vascular endothelial growth factor receptor 2-dependent phosphoinositide 3-kinase/Akt/mTOR/matrix metalloproteinase and p38 MAPK/matrix metalloproteinase pathways,two major pathways for tumor angiogenesis. |
Source |
Molecular Weight | 855.02 |
Formula | C44H70O16 |
CAS No. | 88861-91-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 2 years
( < 1 mg/ml refers to the product slightly soluble or insoluble )
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Sprengerinin C 88861-91-0 Angiogenesis Apoptosis Cytoskeletal Signaling Immunology/Inflammation MAPK PI3K/Akt/mTOR signaling Tyrosine Kinase/Adaptors p38 MAPK NADPH-oxidase PI3K VEGFR ROS Akt mTOR p53 inhibitor inhibit