Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Sprengerinin C exerts anti-tumorigenic effects in hepatocellular carcinoma via inhibition of proliferation and angiogenesis and induction of apoptosis, it can strongly suppress tumor angiogenesis in human umbilical vein endothelial cells, it blocks vascular endothelial growth factor receptor 2-dependent phosphoinositide 3-kinase/Akt/mTOR/matrix metalloproteinase and p38 MAPK/matrix metalloproteinase pathways,two major pathways for tumor angiogenesis.
Description | Sprengerinin C exerts anti-tumorigenic effects in hepatocellular carcinoma via inhibition of proliferation and angiogenesis and induction of apoptosis, it can strongly suppress tumor angiogenesis in human umbilical vein endothelial cells, it blocks vascular endothelial growth factor receptor 2-dependent phosphoinositide 3-kinase/Akt/mTOR/matrix metalloproteinase and p38 MAPK/matrix metalloproteinase pathways,two major pathways for tumor angiogenesis. |
Molecular Weight | 855.02 |
Formula | C44H70O16 |
CAS No. | 88861-91-0 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
( < 1 mg/ml refers to the product slightly soluble or insoluble )
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Sprengerinin C 88861-91-0 MAPK信号通路 PI3K/Akt/mTOR信号通路 蛋白酪氨酸激酶 凋亡 免疫与炎症 细胞骨架 血管生成 p53 p38 MAPK PI3K ROS VEGFR NADPH-oxidase mTOR Akt Inhibitor inhibitor inhibit