Powder: -20°C for 3 years
In solvent: -80°C for 2 years
AMG-1 is a potent inhibitor of human RON and c-Met.In vitro kinase assays showed that compound I is a potent inhibitor of human RON and c-Met with IC50s of 9 and 4 nmol/L, respectively.
Description | AMG-1 is a potent inhibitor of human RON and c-Met.In vitro kinase assays showed that compound I is a potent inhibitor of human RON and c-Met with IC50s of 9 and 4 nmol/L, respectively. |
Targets&IC50 | RON:9 nM, c-Met:4 nM |
Synonyms | AMG-1, RON-IN-1 |
Molecular Weight | 556.58 |
Formula | C31H29FN4O5 |
CAS No. | 913376-84-8 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 90 mg/mL (161.7 mM), Need ultrasonic
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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SYN1143 913376-84-8 Tyrosine Kinase/Adaptors c-Met/HGFR SYN-1143 tumor RON dual inhibit AMG-1 SYN 1143 cancer RON-IN-1 Inhibitor c-Met inhibitor