store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SR 11302 is an inhibitor of activator protein-1 (AP-1).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | Inquiry | $ 1,870.00 | |
10 mg | Inquiry | Inquiry | |
25 mg | Inquiry | Inquiry | |
50 mg | Inquiry | Inquiry | |
100 mg | Inquiry | Inquiry | |
1 mL * 10 mM (in DMSO) | Inquiry | $ 2,258.00 |
Description | SR 11302 is an inhibitor of activator protein-1 (AP-1). |
In vitro | SR 11302 can inhibit the growth of breast cancer cell line T-47D, the lung cancer line Calu-6, and HeLa cells. SR 11302 had very little effect on either the proliferation or the differentiation of HL-60, fresh APL, and NB4 cells[2]. |
In vivo | In an AP-1-luciferase transgenic mouse carcinogenesis model, SR11302 significantly inhibits both AP-1 activations in 7,12-dimethyl benz(a)anthracene-initiated mouse skin and 12-O-tetradecanoylphorbol-13-acetate-induced papilloma formation[3]. |
Molecular Weight | 376.53 |
Formula | C26H32O2 |
CAS No. | 160162-42-5 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/Ml(132.79 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
SR 11302 160162-42-5 Cell Cycle/Checkpoint DNA Damage/DNA Repair DNA/RNA Synthesis acid retinoid Lung RARE Cancer SR11302 response Inhibitor protein-1 SR-11302 inhibit AP-1 retinoic element activator inhibitor