Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Rosamultin has antioxidant, antiinflammatory/antinociceptive properties,and has anti-human immunodeficiency virus (HIV) activity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
20 mg | In stock | $ 140.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 110.00 |
Description | Rosamultin has antioxidant, antiinflammatory/antinociceptive properties,and has anti-human immunodeficiency virus (HIV) activity. |
In vitro | Rosamultin isolated from the root of R. rugosa inhibited HIV-1 protease by 53% at a concentration of 100 microM. |
Kinase Assay | A substrate, His-Lys-Ala-ArgVal-Leu-(pNO2-Phe)-Glu-Ala-Nle-Ser-NH2, Inc. For the HIV1 protease assay, the stock solution of the prepared enzyme was diluted. The extracts or compounds(Rosamultin) tested were dissolved in dimethyl sulfoxide (10% in the reaction mixture). A reaction mixture (5 uL) composed of 1 L of 50 uM sodium acetate (pH 5.0), 1 uL of a substrate solution, 1uL of the plant extract or compound solution, and 2 uL of HIV1 protease solution, was stirred, centrifuged, and then incubated at 37℃ for 1 hour in a microtube. A control reaction was performed under the same conditions without plant extract or compounds. The reaction was stopped by heating at 90 ℃ for 1 minute. Thirty-five microliters of autoclaved water was added into the reaction mixture, and an aliquot of 5 uL was analyzed by high-performance liquid chromatography (HPLC). |
Source |
Molecular Weight | 650.84 |
Formula | C36H58O10 |
CAS No. | 88515-58-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mg/mL (15.36 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Rosamultin 88515-58-6 Microbiology/Virology oxidation-reduction Proteases/Proteasome Antioxidant HIV Protease inhibit Inhibitor Protease antioxidant triterpenoid oxidative stress injury HIV-1 inhibitor