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Nortrachelogenin

Catalog No. TN4675 CAS 34444-37-6

Synonyms: (-)-Nortrachelogenin, (-)-Wikstromol

Nortrachelogenin ((-)-Wikstromol), which can be extracted from Partrinia scabiosaefolia, has antifungal activity and induces membrane disruption and cysteinyl asparagin-dependent apoptosis.

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Nortrachelogenin, CAS 34444-37-6

Pack Size	Availability	Price/USD
1 mg	In stock	$ 217.00
5 mg	In stock	$ 540.00
10 mg	In stock	$ 779.00
25 mg	In stock	$ 1,180.00
50 mg	In stock	$ 1,620.00
1 mL * 10 mM (in DMSO)	In stock	$ 550.00

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Nortrachelogenin ((-)-Wikstromol), which can be extracted from Partrinia scabiosaefolia, has antifungal activity and induces membrane disruption and cysteinyl asparagin-dependent apoptosis.
In vitro	Methanolic extract of the root bark of carissa edulis showed anti-plasmodial activity against the chloroquin-senitive (D6) strains of plasmodium falciparum parasite with an IC50 value of 1.95 Dg/ml. From this extract, a lignan compound Nortrachelogenin was isolated and showed anti-plasmodium activity of 14.50 Dg/ml. The structure was determined on the basis of spectroscopic evidence.[1]

Synonyms	(-)-Nortrachelogenin, (-)-Wikstromol
Molecular Weight	374.38
Formula	C20H22O7
CAS No.	34444-37-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Kebenei J S, et al. Anti-plasmodial activity of Nortrachelogenin from the root bark of Carissa edulis (Vahl). International Journal of Applied Research in Natural Products. 2011, 4(3): 1-5. 2. Lee H, et al. (-)-Nortrachelogenin from Partrinia scabiosaefolia elicits an apoptotic response in Candida albicans. FEMS Yeast Res. 2016 May;16(3):fow013. 3. Lee H, et al. Antibacterial Mechanism of (-)-Nortrachelogenin in Escherichia coli O157. Curr Microbiol. 2016 Jan;72(1):48-54. 4. Hu K, et al. Antifungal, antimitotic and anti-HIV-1 agents from the roots of Wikstroemia indica. Planta Med. 2000 Aug;66(6):564-7.

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Keywords

Nortrachelogenin 34444-37-6 Apoptosis Microbiology/Virology Antifungal (-)-Nortrachelogenin (-)-Wikstromol inhibitor inhibit

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