Powder: -20°C for 3 years | In solvent: -80°C for 1 year
NRX-252262 is a potent enhancer of the interaction between β-Catenin, and its cognate E3 ligase, SCFβ-TrCP, induces mutant β-catenin degradation(EC50:3.8 nM)
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 116.00 | |
5 mg | In stock | $ 287.00 | |
10 mg | In stock | $ 455.00 | |
25 mg | In stock | $ 753.00 | |
50 mg | In stock | $ 1,060.00 | |
100 mg | In stock | $ 1,430.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 347.00 |
Description | NRX-252262 is a potent enhancer of the interaction between β-Catenin, and its cognate E3 ligase, SCFβ-TrCP, induces mutant β-catenin degradation(EC50:3.8 nM) |
Targets&IC50 | β-catenin/SCFβ-TrCP:3.8 nM (EC50) |
In vitro | NRX-252262 also induces S33E/S37A mutant β-catenin degradation at an even lower concentration of ~35?μM |
Molecular Weight | 545.36 |
Formula | C23H17Cl2F3N2O4S |
CAS No. | 2438637-61-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 8 mg/mL (14.67 mM), Sonification is recommended.
You can also refer to dose conversion for different animals. More
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NRX-252262 2438637-61-5 Cytoskeletal Signaling Others Stem Cells Wnt/beta-catenin NRX252262 Beta catenin β-catenin Inhibitor NRX 252262 inhibit inhibitor