Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Inarigivir ammonium (SB-9200 ammonium) is a dinucleotide antiviral compound that significantly reduces HBV DNA in transgenic mice expressing hepatitis B virus. Inarigivir is an agonist of retinoic acid-inducible gene-I (RIG-I) that activates intracellular innate immunity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 396.00 | |
2 mg | In stock | $ 598.00 | |
5 mg | In stock | $ 956.00 | |
10 mg | In stock | $ 1,290.00 | |
25 mg | In stock | $ 1,920.00 | |
50 mg | In stock | $ 2,590.00 | |
100 mg | In stock | $ 3,480.00 |
Description | Inarigivir ammonium (SB-9200 ammonium) is a dinucleotide antiviral compound that significantly reduces HBV DNA in transgenic mice expressing hepatitis B virus. Inarigivir is an agonist of retinoic acid-inducible gene-I (RIG-I) that activates intracellular innate immunity. |
In vitro | Inarigivir exhibits activity against HBV (hepatitis B virus) variants, including those resistant to all approved nucleo(s)tide analogues for chronic hepatitis B treatment[1]. |
In vivo | Administration of 100 mg/kg/day Inarigivir (ip) significantly reduces viral DNA in the liver and shows anti-HBV activity while serum HBV DNA is not reduced. Inarigivir does not affect levels of HBV RNA in liver, levels of HBeAg in serum, or mean titers of HBsAg. The minimal effective dose is identified to be between 1.6 and 0.5 mg/kg/day using liver HBV DNA values[2]. |
Synonyms | ORI-9020 ammonium, SB-9200 ammonium |
Molecular Weight | 604.53 |
Formula | C20H29N8O10PS |
CAS No. | 2172788-92-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 98 mg/mL (162.11 mM)
You can also refer to dose conversion for different animals. More
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Inarigivir ammonium 2172788-92-8 Microbiology/Virology HBV SB-9000 ORI9020 HCV Hepatitis B virus ORI 9020 antiviral inhibit Inarigivir Inhibitor ORI-9020 RIG-I SB9000 SB 9000 ORI-9020 ammonium Huh7 SB-9200 ammonium inhibitor