hcv — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T11541	HCV-IN-30		Others , HCV Protease
	HCV-IN-30 is an HCV NS5A replication complex inhibitor (IC50s: 901 and 102 nM for genotypes 1a and 1b replicons).		Others , HCV Protease
T9577	HCV-IN-31		HCV Protease
	HCV-IN-31 is a HCV inhibitor with an EC50/EC95 of 15.7 μM.		HCV Protease
T11539	HCV-IN-29		HCV Protease
	HCV-IN-29 is a hepatitis C virus (HCV) inhibitor.		HCV Protease
T32050	HCV-371	HCV 371
	HCV-371 is a potent selective HCV NS5B polymerase inhibitor that shows broad inhibitory activity against NS5B RDRP and no inhibitory activity against a set of human polymerases (including mitochondrial DNA polymerase γ a...
TQ0090	Nesbuvir	HCV-796	HCV Protease
	Nesbuvir is a selective hepatitis C virus (HCV) nonstructural protein 5B (NS5B) RNA-dependent polymerase inhibitor.Nesbuvir has an IC50 of 9 nM against hepatocellular carcinoma cells containing 1b HCV replicons.		HCV Protease
T27530	HCV-086	HCV086
	HCV-086, a RNA-directed RNA polymerase (NS5B) inhibitor, is used for the treatment of HCV infection.
T11540	HCV-IN-3		Others
	HCV-IN-3 is a hepatitis C virus (HCV) NS3/4a protein inhibitor (IC50: 20 μM; Kd: 29 μM).		Others
T11548	HCV-IN-7		Others
	HCV-IN-7 is an orally active and potent pan-genotypic HCV NS5A inhibitor (IC50s: 3-47 pM). It shows a superior pan-genotypic profile and a good pharmacokinetic profile coupled with a favorable liver uptake.		Others
TP1468	HCV-IN-4
	HCV-IN-4, a potent and orally active inhibitor of HCV NS5A, demonstrates significant efficacy against genotypes GT1a, GT2b, GT3a, and the GT1a mutations Y93H and L31V. Its half-maximal effective concentrations (EC90s) ar...
T11548L	HCV-IN-7 hydrochloride		Others
	HCV-IN-7 hydrochloride is an orally active and potent pan-genotypic HCV NS5A inhibitor (IC50s: 3-47 pM). It shows a superior pan-genotypic profile and a good pharmacokinetic profile coupled with a favorable liver uptake.		Others
T63566	HCV-IN-33
	HCV-IN-33 (Compound (S)-3i) is an inhibitor of HCV entry.
T79626	HCV-IN-44
	HCV-IN-44 (compound 28) is an inhibitor of the HCV NS5B protein, efficacious in suppressing HCV virus replication and useful for researching HCV infection [1].
T63585	HCV-IN-37
	HCV-IN-37 is a potent inhibitor of HCV. HCV-IN-37 is able to persist in rat plasma after oral administration to rats at a single dose of 15 mg/kg. The high potency of the active derivative HCV-IN-37 is mainly driven by t...
T63567	HCV-IN-34
	HCV-IN-34 is an orally active HCV entry inhibitor. HCV-IN-35 exhibits good antiviral efficacy (EC50: 0.010 μM, CC50 (half of the maximum cytotoxic concentration): 7.50 μM).
T63396	HCV-IN-38
	HCV-IN-38 is a selective, potent, orally active hepatitis C virus (HCV) inhibitor with an EC50 value of 15 nM and an SI value of 431. HCV-IN-38 has a good safety profile and oral pharmacokinetics, exhibiting high anti-HC...
T74625	HCV-IN-41
	HCV-IN-41 (compound 4), a potent inhibitor of the hepatitis C virus (HCV), demonstrates exceptional inhibitory effectiveness across different genotypes, with EC 50 values of 0.006762 nM for genotype 1b, 5.183 nM for 2a, ...
T79625	HCV-IN-43
	HCV-IN-43 (compound 2), an HCV NS5B protein inhibitor, efficiently inhibits HCV virus replication and is utilized in the study of HCV infection [1].
T63406	HCV-IN-35
	HCV-IN-35 is a potent inhibitor of HCV and shows potential for infectious disease research.
T63407	HCV-IN-36
	HCV-IN-36 is an orally active HCV entry inhibitor that exhibits good antiviral activity (EC50: 0.016 μM, CC50 (half of the maximum cytotoxic concentration): 8.78 μM).
T64202	HCV-IN-40
	HCV-IN-39 (Compound 18a) is a potent, orally active nucleoside inhibitor of hepatitis C virus (HCV) that acts on the GT1a replicon (EC50: 0.259 μM), GT1b replicon (EC50: 0.434 μM) and GT1b CES1 replicon (EC50. 0.069 μM).