hbv — TargetMol Chemicals

Cat No.	Product Name	Targets
T77714	HBV-IN-37	HBV
	HBV-IN-37 is an HBV inhibitor with an EC50 value of 10 μM and can be used for hepatitis B disease-related research.	HBV
T36747	HBV-IN-4
	HBV-IN-4, a derivative of phthalazinone, functions as a potent, orally active inhibitor of HBV DNA replication, exhibiting an IC50 value of 14 nM. It effectively induces the formation of genome-free capsids, demonstratin...
T62579	HBV-IN-19
	HBV-IN19 has inhibitory effects on hepatitis B virus (HBV) infection. HBV-IN19 inhibits HBsAg secretion and/or production and can be used in the study of HBV infection (e.g. chronic HBV infection).
T62704	HBV-IN-23
	HBV-IN-23 (Compound 5k) is an inhibitor of HBV DNA replication (IC50: 0.58 μM). HBV-IN-23 inhibits drug-sensitive and drug-resistant strains. HBV-IN-23 induces apoptosis in HepG2 cells and exhibits anti-hepatocellular ca...
T62626	HBV-IN-12
	HBV-IN-12 is a potent inhibitor of hepatitis B surface antigen (HBsAg) (0.001 μM < EC50 ≤ 0.05 μM). HBV-IN-12 is anti-HBV DNA (0.001 μM < EC50 ≤ 0.02 μM).
T78783	HBV-IN-35	HBV
	Compound HBV-IN-35 (Compound 88) serves as an HBV inhibitor and exhibits anti-HBV activity in both mouse and human hepatocytes with EC50 values of 100 nM and 400 nM, respectively [1].	HBV
T62355	HBV-IN-14
	HBV-IN-14 is a pyridinopyrimidinone compound and a potent covalent closed-loop DNA (cccDNA) inhibitor. HBV-IN-14 has potential for the study of HBV infection.
T79767	HBV-IN-41	HBV
	HBV-IN-41 (compound 45) is a potent, orally active inhibitor of Hepatitis B Virus (HBV), exhibiting an EC50 value of 0.027μM [1].	HBV
T61115	HBV-IN-25
	HBV-IN-25 is a novel chemical compound that acts as a potent HBV cccDNA reducer when administered orally. It exhibits significant anti-HBeAg potency and anti-HBV activity, with IC50 values of 0.58 μM and 1.15 μM, respect...
T73249	HBV-IN-15
	HBV-IN-15, a flavone derivative, acts as a potent inhibitor of covalently closed circular DNA (cccDNA), which is crucial for viral RNA transcription and subsequent viral DNA production. This compound shows promise for re...
T79879	HBV-IN-38	HBV
	HBV-IN-38 (Example 193), an HBV DNA inhibitor with an EC50 value of ≤100 nM, serves as a research tool for investigating viral infections [1].	HBV
T73280	HBV-IN-29
	HBV-IN-29 (ex8), a flavone derivative, functions as a potent inhibitor of covalently closed circular DNA (cccDNA), which is essential for viral RNA transcription and subsequent viral DNA replication. This compound shows ...
T73281	HBV-IN-30
	HBV-IN-30 (ex44), a flavone derivative, acts as a potent inhibitor of covalently closed circular DNA (cccDNA), which is essential for viral RNA transcription and subsequent viral DNA production. This compound shows promi...
T63162	HBV-IN-22
	HBV-IN-22 (Compound LC5f) is an HBV DNA replication inhibitor that acts on both wild-type HBV (IC50: 0.71 μM) and drug-resistant HBV (IC50: 0.84 μM).
T63795	HBV-IN-6
	HBV-IN-6 is a potent inhibitor of HBV (EC50: 44 nM).
T62115	HBV-IN-24
	HBV-IN-24 (compound (2 S, 6S)-1a) is a potent inhibitor of HBV. HBV-IN-24 is a strong inhibitor of HBV DNA (EC50: 0.6 nM), HBsAg (EC50: 0.6 nM) and HBeAg (EC50: 4.6 nM). antiviral effect and was able to improve neurotoxi...
T62467	HBV-IN-18
	HBV-IN-18 (Compound 3) is an HBV capsid assembly modulator (CpAM) (EC50: 2790 nM).
T64260	HBV-IN-20
	HBV-IN-20 is a potent, orally active HBV inhibitor (EC50: 0.46 μM). HBV-IN-20 is a classical type II CpAM (core protein assembly regulator).
T61558	HBV-IN-21
	HBV-IN-21 (Compound II-8b) is a potent inhibitor of HBV DNA replication, exhibiting an IC50 of 2.2 μM. It demonstrates a favorable binding affinity (K D = 60.0 μM) for the HBV 4 capsid protein, thereby enabling effective...
T79650	HBV-IN-40	HBV
	HBV-IN-40 (Compound 11826096), with an IC50 of 0.7 µM, serves as a potent HBV inhibitor and exhibits antiviral activity [1].	HBV