Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Glycolic acid is an inhibitor of tyrosinase, suppressing melanin formation,and used in skincare products
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 mg | In stock | $ 41.00 | |
1 g | In stock | $ 48.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 45.00 |
Description | Glycolic acid is an inhibitor of tyrosinase, suppressing melanin formation,and used in skincare products |
In vivo | Glycolic acid(GA) reduced the production of UVB-induced nuclear factor kappa B (NF-κB)-dependent inflammatory mediators [interleukin (IL)-1β, IL-6, IL-8, cyclooxygenase (COX)-2, tumor necrosis factor-α, and monocyte chemoattractant protein (MCP-1)] at both mRNA and protein levels. GA inhibited the UVB-induced promoter activity of NF-κB in HaCaT cells. GA attenuated the elevation of senescence associated with β-galactosidase activity but did not affect the wound migration ability. The topical application of GA inhibited the genes expression of IL-1β, IL-6, IL-8, COX-2, and MCP-1 in UVB-exposed mouse skin. The mice to UVB irradiation after GA was topically applied for 9 consecutive days and reported that 1-1.5% of GA exerted anti-inflammatory effects on mouse skin[1] |
Animal Research | The effects of different concentrations of Glycolic acid(GA) on the inflammatory response of human keratinocytes HaCaT cells and C57BL/6J mice dorsal skin.?After GA was topically applied, HaCaT and mice skin were exposed to UVB irradiation[1]. |
Molecular Weight | 76.05 |
Formula | C2H4O3 |
CAS No. | 79-14-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (1314.92 mM)
You can also refer to dose conversion for different animals. More
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Glycolic acid 79-14-1 Metabolism Proteases/Proteasome Endogenous Metabolite Tyrosinase Inhibitor inhibit inhibitor