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Evodiamine
🥰Excellent
Catalog No. T2868Cas No. 518-17-2
Alias Isoevodiamine, d-Evodiamine, (+)-Evodiamine
Evodiamine (d-Evodiamine) is an alkaloid isolated from the fruit of daylily and has a variety of biological activities including anti-inflammatory, anti-obesity and anti-tumor.
Evodiamine
🥰Excellent
Purity: 99.94%
Catalog No. T2868Alias Isoevodiamine, d-Evodiamine, (+)-EvodiamineCas No. 518-17-2
Evodiamine (d-Evodiamine) is an alkaloid isolated from the fruit of daylily and has a variety of biological activities including anti-inflammatory, anti-obesity and anti-tumor.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 mg | $30 | In Stock | |
| 50 mg | $42 | In Stock | |
| 100 mg | $54 | In Stock | |
| 200 mg | $80 | In Stock | |
| 500 mg | $129 | In Stock | |
| 1 g | $192 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $46 | In Stock |
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Purity:99.94%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Evodiamine (d-Evodiamine) is an alkaloid isolated from the fruit of daylily and has a variety of biological activities including anti-inflammatory, anti-obesity and anti-tumor. |
| In vitro | In mice, the LD50 of intravenously injected Evodiamine is 77 mg/kg. |
| In vivo | In U937 cells with overexpressed Bcl-2 and Akt, evodiamine induces apoptosis through a caspase-independent cell death pathway. |
| Cell Research | Evodiamine is dissolved in DMSO and diluted with appropriate medium before use. The evodiamine-inspired new scaffolds are assayed for growth inhibitory activities toward human cancer cell-lines A549 (lung cancer), MDA-MB-435 (breast cancer) and HCT116 (colon cancer) using the MTT assay. Evodiamine and camptithecin are used as reference drugs[1]. |
| Synonyms | Isoevodiamine, d-Evodiamine, (+)-Evodiamine |
| Molecular Weight | 303.36 |
| Formula | C19H17N3O |
| Cas No. | 518-17-2 |
| Smiles | CN1[C@@]2(C3=C(C=4C(N3)=CC=CC4)CCN2C(=O)C=5C1=CC=CC5)[H] |
| Relative Density. | 1.1684 g/cm3 (Estimated) |
| Color | White |
| Appearance | Solid |
Storage & Solubility Information
| Storage | keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 6.25 mg/mL (20.6 mM), Sonication is recommended.  | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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