Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Evodiamine (d-Evodiamine) is an alkaloid isolated from the fruit of daylily and has a variety of biological activities including anti-inflammatory, anti-obesity and anti-tumor.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
50 mg | In stock | $ 42.00 | |
100 mg | In stock | $ 54.00 | |
250 mg | In stock | $ 91.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 46.00 |
Description | Evodiamine (d-Evodiamine) is an alkaloid isolated from the fruit of daylily and has a variety of biological activities including anti-inflammatory, anti-obesity and anti-tumor. |
In vitro | In mice, the LD50 of intravenously injected Evodiamine is 77 mg/kg. |
In vivo | In U937 cells with overexpressed Bcl-2 and Akt, evodiamine induces apoptosis through a caspase-independent cell death pathway. |
Cell Research | Evodiamine is dissolved in DMSO and diluted with appropriate medium before use. The evodiamine-inspired new scaffolds are assayed for growth inhibitory activities toward human cancer cell-lines A549 (lung cancer), MDA-MB-435 (breast cancer) and HCT116 (colon cancer) using the MTT assay. Evodiamine and camptithecin are used as reference drugs[1]. |
Source |
Synonyms | d-Evodiamine, Isoevodiamine, (+)-Evodiamine |
Molecular Weight | 303.36 |
Formula | C19H17N3O |
CAS No. | 518-17-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 6.25 mg/mL (20.6 mM)
You can also refer to dose conversion for different animals. More
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Evodiamine 518-17-2 GPCR/G Protein Immunology/Inflammation Prostaglandin Receptor inhibit Inhibitor d-Evodiamine Isoevodiamine (+)-Evodiamine inhibitor