keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Dolastatin 10 (DLS 10) is a powerful peptide with antimitotic properties, effectively inhibiting tubulin polymerization.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 213.00 | |
2 mg | In stock | $ 318.00 | |
5 mg | In stock | $ 538.00 | |
10 mg | In stock | $ 793.00 | |
25 mg | In stock | $ 1,180.00 | |
50 mg | In stock | $ 1,630.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 769.00 |
Description | Dolastatin 10 (DLS 10) is a powerful peptide with antimitotic properties, effectively inhibiting tubulin polymerization. |
In vitro | Dolastatin 10 is a unique pentapeptide that isolated from the sea hare?Dolabella auricularia. These in vitro data are quite comparable to those of Dolastatin 10 and Auristatin PE, each of which has GI50?values of 10?5-10?6?μg/mL (10?2-10?3?nM) against a similar minipanel of human cell lines[1]. The antibody-drug conjugate (ADC) comprises the anti-CD30 monoclonal antibody cAC10 conjugated to the cytotoxic agent monomethyl auristatin E (MMAE), a synthetic analog of the tubulin polymerization inhibitor Dolastatin 10[2]. |
Synonyms | NSC 376128, DLS 10 |
Molecular Weight | 785.09 |
Formula | C42H68N6O6S |
CAS No. | 110417-88-4 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (127.37 mM)
You can also refer to dose conversion for different animals. More
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Dolastatin 10 110417-88-4 Cytoskeletal Signaling Microtubule Associated DLS10 ADC Cytotoxin Dolastatin-10 NSC 376128 DLS-10 inhibit NSC376128 Dolastatin10 Inhibitor NSC-376128 ADC Payload Microtubule/Tubulin DLS 10 inhibitor