Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Dithranol (cignoline) is an anthracene derivative that disrupts MITOCHONDRIA function and structure and is used for the treatment of DERMATOSES, especially PSORIASIS. It may cause FOLLICULITIS.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
50 mg | In stock | $ 34.00 | |
100 mg | In stock | $ 50.00 | |
200 mg | In stock | $ 63.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 37.00 |
Description | Dithranol (cignoline) is an anthracene derivative that disrupts MITOCHONDRIA function and structure and is used for the treatment of DERMATOSES, especially PSORIASIS. It may cause FOLLICULITIS. |
Kinase Assay | THP-1 and HEK293 cells are transiently transfected using DEAE-dextran and Polyfect reagent, respectively. Plasmids transfected contain genes coding for the NF-κB-dependent pELAM-luc luciferase reporter, TLR2, TLR4, CD14, and MD2. Cells (5×105 THP-1 or 1×105 HEK293) are added to 12-well plates, washed after 18 h, and stimulated for 5 h. Cells are then lysed with reporter lysis buffer as directed, and lysates are analyzed for luminescence using Promega luciferase substrate and a Monolight 3010 luminometer. |
Synonyms | 1,8,9-trihydroxyanthracene, cignoline, Anthralin |
Molecular Weight | 226.23 |
Formula | C14H10O3 |
CAS No. | 1143-38-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Chloroform: 41 mg/mL
DMSO: 10 mM
You can also refer to dose conversion for different animals. More
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Dithranol 1143-38-0 Cell Cycle/Checkpoint DNA Damage/DNA Repair Others DNA/RNA Synthesis plaques 1,8,9-trihydroxyanthracene repair cignoline replication psoriatic Anthralin DNA Inhibitor inhibit inhibitor