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Dexpramipexole
🥰Excellent
Catalog No. TQ0175Cas No. 104632-28-2
Dexpramipexole ((R)-Pramipexole), a BTZ structural analog of riluzole, is a mitochondrial protectant that maintains mitochondrial function and energy production, attenuates myocardial ischemia/reperfusion injury by up-regulating mitochondrial autophagy, and can be used in the treatment of amyotrophic lateral sclerosis disease.
Dexpramipexole
🥰Excellent
Purity: 99.78%
Catalog No. TQ0175Cas No. 104632-28-2
Dexpramipexole ((R)-Pramipexole), a BTZ structural analog of riluzole, is a mitochondrial protectant that maintains mitochondrial function and energy production, attenuates myocardial ischemia/reperfusion injury by up-regulating mitochondrial autophagy, and can be used in the treatment of amyotrophic lateral sclerosis disease.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $397 | In Stock | |
| 5 mg | $970 | In Stock | |
| 10 mg | $1,290 | In Stock | |
| 25 mg | $1,950 | In Stock |
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Purity:99.78%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Dexpramipexole ((R)-Pramipexole), a BTZ structural analog of riluzole, is a mitochondrial protectant that maintains mitochondrial function and energy production, attenuates myocardial ischemia/reperfusion injury by up-regulating mitochondrial autophagy, and can be used in the treatment of amyotrophic lateral sclerosis disease. |
| In vitro | Dexpramipexole is neuroprotective and has been used in research studies for the treatment of amyotrophic lateral sclerosis (ALS). Dexpramipexole reduces mitochondrial reactive oxygen species (ROS) production, inhibits activation of apoptotic pathways, and improves cell survival in response to a variety of neurotoxins and beta-amyloid neurotoxicity. Dexpramipexole is much less active than dopamine agonists of the S-(-) isomer. [1] |
| Molecular Weight | 211.33 |
| Formula | C10H17N3S |
| Cas No. | 104632-28-2 |
| Smiles | NC1=NC2=C(C[C@H](NCCC)CC2)S1 |
| Relative Density. | 1.17 g/cm3 at 20℃ |
Storage & Solubility Information
| Storage | keep away from direct sunlight,store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 8 mg/mL (37.86 mM), Sonication is recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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