Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Darodipine (PY-108068) is a dihydropyridine type Ca+2 antagonist.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 55.00 | |
2 mg | In stock | $ 78.00 | |
5 mg | In stock | $ 112.00 | |
10 mg | In stock | $ 157.00 | |
25 mg | In stock | $ 288.00 | |
50 mg | In stock | $ 497.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 137.00 |
Description | Darodipine (PY-108068) is a dihydropyridine type Ca+2 antagonist. |
In vivo | Darodipine may reduce neuronal cytoskeletal changes occurring in aging and in neurodegenerative disorders. Darodipine (10 mg/kg; 6-month (from the 18th to the 24th month of life); p.o.) treatment restores in part the expression of 200 kDa-NF subunit immunoreactivity in the cerebellar cortex [2]. Treatment with darodipine increases the number and the average length of alkaline phosphatase-reactive capillaries and reduces the intercapillary distance and the diameter of cerebral capillaries in old rats. The pericapillary microrenvironment of the Ammon's horn is the most sensitive to treatment with darodipine [1]. |
Synonyms | PY-108068, PY 108-068 |
Molecular Weight | 371.39 |
Formula | C19H21N3O5 |
CAS No. | 72803-02-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 60 mg/ml (161.56 mM)
You can also refer to dose conversion for different animals. More
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Darodipine 72803-02-2 Membrane transporter/Ion channel Metabolism Calcium Channel Ca channels PY 108068 PY-108068 PY 108-068 PY108068 Ca2+ channels Inhibitor inhibit inhibitor