Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Azoramide, a small-molecule modulator, has the antidiabetic activity of unfolded protein response.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 43.00 | |
10 mg | In stock | $ 52.00 | |
25 mg | In stock | $ 101.00 | |
50 mg | In stock | $ 158.00 | |
100 mg | In stock | $ 288.00 | |
500 mg | In stock | $ 693.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 48.00 |
Description | Azoramide, a small-molecule modulator, has the antidiabetic activity of unfolded protein response. |
In vitro | Azoramide, a dual-function endoplasmic reticulum (ER) modulator, improves ER protein-folding ability and activates ER chaperone capacity to protect cells against ER stress in multiple systems. |
In vivo | In two independent mouse models of obesity, Azoramide exhibits potent antidiabetic efficacy by improving insulin sensitivity and pancreatic β cell function. |
Molecular Weight | 308.83 |
Formula | C15H17ClN2OS |
CAS No. | 932986-18-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 30.9 mg/mL(100 mM)
You can also refer to dose conversion for different animals. More
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Azoramide 932986-18-0 Apoptosis PERK mitochondrial function ER protein fold antidiabetic inhibit CERB signaling ER chaperone capacity Inhibitor unfolded protein response DA neurons inhibitor