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Alismol

Catalog No. TN1367 CAS 87827-55-2

Synonyms: 泽泻醇

Alismol has antihypertensive action, it decreases cardiac output, heart rate and left ventricular pressure, but it increases coronary flow, it has been used for the prevention of anginal attacks.

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Alismol, CAS 87827-55-2

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Alismol has antihypertensive action, it decreases cardiac output, heart rate and left ventricular pressure, but it increases coronary flow, it has been used for the prevention of anginal attacks.

In vitro

Alismol (10(-6) to 10(-4) M) inhibited the contraction of isolated rabbit ear artery by electrical stimulation of the perivascular nerves. The inhibition was concentration-dependent; at a concentration of 10(-4) M, the inhibition was 90% (n = 8). Treatment with 10(-4) M Alismol inhibited the increase in 3H-noradrenaline (3H-NAd) release induced by electrical stimulation by 63 +/- 6%. Alismol at 10(-4) M did not affect the neuronal uptake of 3H-NAd in the artery. Alismol at 10(-4) M slightly inhibited contractions induced by exogenously administered NAd[1]

Synonyms	泽泻醇
Molecular Weight	220.35
Formula	C15H24O
CAS No.	87827-55-2

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Effect of alismol on adrenergic mechanism in isolated rabbit ear artery.Jpn J Pharmacol. 1988 Apr;46(4):331-5.

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Keywords

Alismol 87827-55-2 PI3K/Akt/mTOR信号通路代谢离子通道 PI3K Potassium Channel Calcium Channel Inhibitor inhibitor inhibit

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