Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AX20017 is a small-molecule protein kinase G (PknG) inhibitor(IC50 : 0.39 μM). It acts by blocking the proliferation of M. tuberculosis.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | In stock | $ 43.00 | |
5 mg | In stock | $ 65.00 | |
10 mg | In stock | $ 92.00 | |
25 mg | In stock | $ 198.00 | |
50 mg | In stock | $ 343.00 | |
100 mg | In stock | $ 516.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 75.00 |
Description | AX20017 is a small-molecule protein kinase G (PknG) inhibitor(IC50 : 0.39 μM). It acts by blocking the proliferation of M. tuberculosis. |
Targets&IC50 | PKNG:0.39 μM |
In vitro | The inhibitory activity of AX20017 against the 11 known mycobacterial kinases revealed that the compound is highly selective for PknG . To test the activity of the inhibitor toward eukaryotic kinases, a screen of 28 different archetypical human kinases originating from six major protein kinase groups was set up. AX20017 did not affect the human kinases, whereas the activity of PknG was effectively inhibited[1]. |
Molecular Weight | 264.34 |
Formula | C13H16N2O2S |
CAS No. | 329221-38-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 32 mg/mL (121.06 mM)
You can also refer to dose conversion for different animals. More
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AX20017 329221-38-7 Microbiology/Virology Others Antibacterial Inhibitor AX-20017 Bacterial inhibit AX 20017 inhibitor