Powder: -20°C for 3 years | In solvent: -80°C for 2 years
2-(Methylamino)-1H-purin-6(7H)-one is an endogenous methylated nucleoside found in human fluids and a modified nucleoside.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 64.00 | |
5 mg | In stock | $ 147.00 | |
10 mg | In stock | $ 239.00 | |
25 mg | In stock | $ 392.00 | |
50 mg | In stock | $ 597.00 | |
100 mg | In stock | $ 852.00 |
Description | 2-(Methylamino)-1H-purin-6(7H)-one is an endogenous methylated nucleoside found in human fluids and a modified nucleoside. |
In vitro | 2-(Methylamino)-1H-purin-6(7H)-one is the principal kinetic barrier for reverse transcription in the 1340 bases proximal to the 5' end of E. coli 16S rRNA. Transcription intermediates correspond to attenuation at the positions of 2-(Methylamino)-1H-purin-6(7H)-one in the rRNA sequence. The relaxation time for elongation of the cDNA through m2G is approximately 3 min[1]. 2-(Methylamino)-1H-purin-6(7H)-one is found within both helical and looped regions of RNA secondary structure, and it can exist in either the s-cis or the s-trans rotamer. If there is a rotational preference for the methyl group, the effect of 2-(Methylamino)-1H-purin-6(7H)-one substitution may be specific to the sequence context depending upon which face of the base participates in hydrogen bonding[2]. |
Synonyms | N2-methylguanine |
Molecular Weight | 165.15 |
Formula | C6H7N5O |
CAS No. | 10030-78-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 2 years
DMSO: < 1 mg/mL (insoluble or slightly soluble)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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2-(Methylamino)-1H-purin-6(7H)-one 10030-78-1 Cell Cycle/Checkpoint DNA Damage/DNA Repair Metabolism Microbiology/Virology Antibacterial DNA/RNA Synthesis Endogenous Metabolite Inhibitor Bacterial 2 (Methylamino) 1H purin 6(7H) one 2(Methylamino)1Hpurin6(7H)one N2-methylguanine inhibit inhibitor