Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(+)-Fluprostenol (AL-5848), an analogue of prostaglandin F2 alpha, is a prostaglandin F2α receptor PTGFR agonist and decreases the expression of Oviductal glycoprotein 1 (OVGP1).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 77.00 | |
5 mg | In stock | $ 189.00 | |
10 mg | In stock | $ 313.00 | |
25 mg | In stock | $ 578.00 | |
50 mg | In stock | $ 833.00 | |
100 mg | In stock | $ 1,150.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 223.00 |
Description | (+)-Fluprostenol (AL-5848), an analogue of prostaglandin F2 alpha, is a prostaglandin F2α receptor PTGFR agonist and decreases the expression of Oviductal glycoprotein 1 (OVGP1). |
In vivo | (+)-Fluprostenol(s.c. to rats on day 18 of pregnancy) increased cervical creep, or softness, by the following day. Doses of (+)-Fluprostenol 100-fold larger were necessary to increase uterine contractions. (+)-Fluprostenol produced falls in serum progesterone concentrations, increases in 20 alpha-dihydroprogesterone concentrations, no changes in oestradiol or relaxin concentrations and a reduction in the ovarian human chorionic gonadotrophin binding capacity in vitro. (+)-Fluprostenol was less potent in inducing cervical softness when administered per vaginam, and a dose which produced softening in pregnant rats was ineffective in ovariectomized steroid-maintained pregnant or pro-oestrous rats[3]. |
Synonyms | Fluprostenol, (+)-, Travoprost acid, AL-5848 |
Molecular Weight | 458.47 |
Formula | C23H29F3O6 |
CAS No. | 54276-17-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 325 mg/mL (708.88 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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(+)-Fluprostenol 54276-17-4 GPCR/G Protein Immunology/Inflammation Prostaglandin Receptor AL 5848 PTGER2 Fluprostenol, (+)- Travoprost acid Oviductal glycoprotein 1 Fluprostenol, (+) Fluprostenol inhibit Fluprostenol (+)Fluprostenol AL-5848 OVGP1 Inhibitor AL5848 inhibitor