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Taprenepag isopropyl
😃Good
Catalog No. T16988Cas No. 1005549-94-9
Alias PF-04217329
Taprenepag isopropyl is a highly selective agonist of the EP2 receptor.
Taprenepag isopropyl
😃Good
Catalog No. T16988Alias PF-04217329Cas No. 1005549-94-9
Taprenepag isopropyl is a highly selective agonist of the EP2 receptor.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $48 | 5 days |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Taprenepag isopropyl is a highly selective agonist of the EP2 receptor. |
| In vivo | Intraocular pressure (IOP) typically stays within normal limits in the left eye treated with a vehicle solution, while the right eye, dosed with Taprenepag isopropyl, shows a reduction in IOP across all dosage groups. Notably, in the high-dose group, IOP decreases to levels below measurable thresholds (<4mm Hg) on Days 22 and 29. Administration of Taprenepag isopropyl, regardless of the dose, does not result in clinical signs, body weight changes, or ocular findings in the animals receiving the lowest dose (0.75 mg/day) [1]. |
| Alias | PF-04217329 |
| Molecular Weight | 520.6 |
| Formula | C27H28N4O5S |
| Cas No. | 1005549-94-9 |
| Relative Density. | 1.26 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Sci Citations
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
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