T8468 |
CIL62
|
117593-36-9
|
97.74%
|
|
CIL62 is a caspase-3/7-independent inducer of cell death. The mechanism of action of CIL62 is Necrostatin-1 dependent cell death [1].
|
T8296 |
5,7,4'-Trimethoxyflavone
|
5631-70-9
|
97.53%
|
|
5,7,4'-Trimethoxyflavone (4',5,7-Trimethoxyflavone) is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand.
|
T36347 |
Ac-YVAD-CMK
|
178603-78-6
|
97.08%
|
|
Ac-YVAD-CMK (Ac-Tyr-Val-Ala-Asp-CMK) is a selective and irreversible inhibitor of Caspase-1 and inhibits pyroptosis, IL-1β and IL-18. Ac-YVAD-CMK shows neuroprot...
|
TN2097 |
Pomolic acid
|
13849-91-7
|
96.84%
|
|
Pomolic acid has anti-cancer, anti-inflammatory and apoptotic activities, it can induce apoptosis in SK-OV-3 cells, which is mediated by the mitochondrial-mediat...
|
TN1405 |
Arnicolide D
|
34532-68-8
|
96.66%
|
|
Arnicolide D is a sesquiterpene lactone. Arnicolide D isolates from Centipeda minima. Arnicolide D modulates the cell cycle, activates the caspase signaling path...
|
T2881 |
Crustecdysone
|
5289-74-7
|
96.31%
|
|
Crustecdysone (Hydroxyecdysone) is a steroid hormone that regulates the processes of molting or ecdysis in insects.
|
TN2175 |
Salvianolic acid F
|
158732-59-3
|
96.01%
|
|
The role of our hybrid molecules, an analogue of Salvianolic acid F, in compelling the glioma cells towards apoptosis by specifically perturbing the concentratio...
|
T36534 |
SDZ 224-015
|
161511-45-1
|
95.49%
|
|
SDZ 224-015 is an orally active inhibitor of interleukin-1β (IL-1β) converting enzyme and caspase-1.SDZ 224-015 exhibits anti-COVID-19 and anti-inflammatory acti...
|
T36819 |
Ac-FLTD-CMK
|
2376255-48-8
|
95.17%
|
|
Ac-FLTD-CMK is an inhibitor derived from abscisicin D (GSDMDD) with specific inhibitory effects on inflammatory caspases. ac-FLTD-CMK showed inhibitory effects o...
|
T7374 |
2-HBA
|
131359-24-5
|
95.01%
|
|
2-HBA, a synthetic analog of curcumin, is an indirect inducer of enzymes that catalyze detoxification reactions through the Keap1-Nrf2-ARE pathway.
|
T3519 |
Formosanin C
|
50773-42-7
|
100%
|
|
Formosanin C (Polyphyllin B) is a compound isolated from Rhizoma Paridis, showed pro-apoptosis and immunoregulation with antitumor activity in cultured cells and...
|
T0282 |
Q-VD-OPH
|
1135695-98-5
|
100%
|
|
Q-VD-OPH (Quinoline-Val-Asp-Difluorophenoxymethylketone) is a pan-caspase inhibitor with potent antiapoptotic properties.
|
T6013 |
Z-VAD(OMe)-FMK
|
187389-52-2
|
|
|
Z-VAD(OMe)-FMK (Z-Val-Ala-Asp(OMe)-FMK) is a broad-spectrum inhibitor of caspases that is cell-permeable and irreversible. Z-VAD(OMe)-FMK binds to activated casp...
|
T10580 |
BOC-D-FMK
|
634911-80-1
|
|
|
Boc-D-FMK is an irreversible, cell-permeable, and broad-spectrum caspase inhibitor and inhibits apoptosis stimulated by TNF-α (IC50: 39 µM).
|
T3907 |
Tenuigenin
|
2469-34-3
|
|
|
Tenuigenin (Senegenin) is a natural product from Polygala tenuifolia used in Chinese medicine with antioxidative and anti-inflammatory activity.
|
TN3967 |
Epieriocalyxin A
|
191545-24-1
|
|
|
Epieriocalyxin A can suppress Caco-2 colon cancer cell growth. It could be a potential drug for colon cancer therapy in the future.
|
T8092 |
Taurohyodeoxycholic acid sodium salt
|
38411-85-7
|
|
|
Taurohyodeoxycholic acid sodium salt (Sodium taurohyodeoxycholate hydrate) prevents apoptosis by blocking a calcium-mediated apoptotic pathway as well as caspase...
|
T3123 |
Allicin
|
539-86-6
|
|
|
Allicin exerts antioxidant, bactericidal, anti-cancer, anti-inflammatory activities, it exerts an inhibitory immunomodulatory effect on intestinal epithelial cel...
|
T78631 |
Ac-YVAD-AOM
|
154674-81-4
|
98%
|
|
Ac-YVAD-AOM is a selective and potent caspase-1 inhibitor showing antitumor activity and potential analgesic activity.
|
T83653 |
SACLAC
|
2248703-42-4
|
98%
|
|
SACLAC is a cysteine asparaginase activation inhibitor with antitumor activity that decreases AML cell viability, inhibits AML cell proliferation, increases AML ...
|