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Apoptosis

Apoptosis is a form of programmed cell death that occurs in multicellular organisms. Biochemical events lead to characteristic cell changes (morphology) and death. These changes include blebbing, cell shrinkage, nuclear fragmentation, chromatin condensation, DNA fragmentation, and mRNA decay.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T2078 Fimepinostat 1339928-25-4 99.66%
Fimepinostat
Fimepinostat (CUDC 907) is an orally bioavailable inhibitor of both phosphoinositide 3-kinase (PI3K) class I and pan-histone deacetylase (HDAC) enzymes, with pot...
TNU0352 1-beta-D-Arabinofuranosylthymine 605-23-2 99.65%
1-beta-D-Arabinofuranosylthymine
1-beta-D-Arabinofuranosylthymine (Thymine 1-β-D-arabinofuranoside) is a purine nucleoside analog. Purine nucleoside analogs have a broad spectrum of antitumor ac...
T6909 NSC348884 81624-55-7 99.65%
NSC348884
NSC348884 is a nucleophosmin inhibitor disrupts oligomer formation and induces apoptosis, inhibits cell proliferation at an IC50 of 1.7-4.0 μM in distinct cancer...
T8445 PU02 313984-77-9 99.65%
PU02
PU02 (6-[(1-Naphthalenylmethyl)thio]-9H-purine) is a potent and selective antagonist of 5-HT3 receptor.
T41288 Myristoleic acid 544-64-9 99.65%
Myristoleic acid
Myristoleic acid (9-Tetradecenoic acid) is a cytotoxic component in the extract from Serenoa repens. Myristoleic acid induces apoptosis and necrosis in human pro...
T1890 Pracinostat 929016-96-6 99.65%
Pracinostat
Pracinostat (SB939) is a novel HDAC inhibitor with improved in vivo properties compared to other HDAC inhibitors currently in Clinicalal trials, allowing oral do...
TN4673 (+)-Nortrachelogenin 61521-74-2 99.64%
(+)-Nortrachelogenin
(+)-Nortrachelogenin is a lignan isolated from Wikstroemia indica C.A. Meyer (Thymelaeaceae). (+)-Nortrachelogenin possesses antileukemic activity.
T0649 Salicylic acid 69-72-7 99.64%
Salicylic acid
Salicylic acid (2-Hydroxybenzoic acid), a natural compound extracted from Willow bark, is an anti-inflammatory inhibitor of activity cyclooxygenase.
T2145 Temsirolimus 162635-04-3 99.64%
Temsirolimus
Temsirolimus (CCI-779) is a specific mTOR inhibitor ( IC50: 1.76 μM), used in the treatment of advanced renal cell cancer.
T6308 Stattic 19983-44-9 99.64%
Stattic
Stattic (STAT3 Inhibitor V) is a STAT3 inhibitor (IC50=5.1 μM) that selectively inhibits STAT3 activation, dimerization, and nuclear translocation. Stattic has a...
T4036 Solasodine 126-17-0 99.64%
Solasodine
Solasodine (Purapuridine)(Purapuridine) is a poisonous alkaloid chemical compound that occurs in plants of the Solanaceae family. Solasodine showed selective cyt...
T6928 Pantoprazole 102625-70-7 99.63%
Pantoprazole
Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disea...
T14371 Barasertib 722543-31-9 99.63%
Barasertib
AZD1152 is a pro-drug of Barasertib (AZD1152)-hQPA. Which is a highly selective Aurora B inhibitor with IC50 of 0.37 nM in a cell-free assay.
T0291 Flurbiprofen 5104-49-4 99.63%
Flurbiprofen
Flurbiprofen (dl-Flurbiprofen) is an anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption i...
T16901 SMIP004 143360-00-3 99.63%
SMIP004
SMIP004 is an SKP2 E3 ligase inhibitor. SMIP004 is a cancer cell-selective apoptosis inducer of human prostate cancer cells.
T3S1227 Aristolactam I 13395-02-3 99.63%
Aristolactam I
1.Aristolactam I (Aristololactum) has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway. 2. The effects of Aristolo...
T3094 PS-1145 431898-65-6 99.63%
PS-1145
PS-1145 (IKK Inhibitor X) is a specific IKK inhibitor with IC50 of 88 nM.
T8461 SKI V 24418-86-8 99.62%
SKI V
SKI V is a potent and noncompetitive non-lipid sphingosine kinase (SPHK; SK) inhibitor (GST-hSK,IC50 : 2 μM), and is a PI3K inhibitor(hPI3k,IC50 : 6 μM), induces...
T3151 Brassinolide 72962-43-7 99.62%
Brassinolide
Brassinolide (Brassin lactone) is a plant hormone isolated from rapeseed (Brassica napus) promoting stem elongation and cell division.
T6539 Ibandronate sodium monohydrate 138926-19-9 99.62%
Ibandronate sodium monohydrate
Ibandronate sodium monohydrate (BM-210955) is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis.
Fimepinostat
T2078
Fimepinostat (CUDC 907) is an orally bioavailable inhibitor of both phosphoinositide 3-kinase (PI3K) class I and pan-histone deacetylase (HDAC) enzymes, with pot...
1-beta-D-Arabinofuranosylthymine
TNU0352
1-beta-D-Arabinofuranosylthymine (Thymine 1-β-D-arabinofuranoside) is a purine nucleoside analog. Purine nucleoside analogs have a broad spectrum of antitumor ac...
NSC348884
T6909
NSC348884 is a nucleophosmin inhibitor disrupts oligomer formation and induces apoptosis, inhibits cell proliferation at an IC50 of 1.7-4.0 μM in distinct cancer...
PU02
T8445
PU02 (6-[(1-Naphthalenylmethyl)thio]-9H-purine) is a potent and selective antagonist of 5-HT3 receptor.
Myristoleic acid
T41288
Myristoleic acid (9-Tetradecenoic acid) is a cytotoxic component in the extract from Serenoa repens. Myristoleic acid induces apoptosis and necrosis in human pro...
Pracinostat
T1890
Pracinostat (SB939) is a novel HDAC inhibitor with improved in vivo properties compared to other HDAC inhibitors currently in Clinicalal trials, allowing oral do...
(+)-Nortrachelogenin
TN4673
(+)-Nortrachelogenin is a lignan isolated from Wikstroemia indica C.A. Meyer (Thymelaeaceae). (+)-Nortrachelogenin possesses antileukemic activity.
Salicylic acid
T0649
Salicylic acid (2-Hydroxybenzoic acid), a natural compound extracted from Willow bark, is an anti-inflammatory inhibitor of activity cyclooxygenase.
Temsirolimus
T2145
Temsirolimus (CCI-779) is a specific mTOR inhibitor ( IC50: 1.76 μM), used in the treatment of advanced renal cell cancer.
Stattic
T6308
Stattic (STAT3 Inhibitor V) is a STAT3 inhibitor (IC50=5.1 μM) that selectively inhibits STAT3 activation, dimerization, and nuclear translocation. Stattic has a...
Solasodine
T4036
Solasodine (Purapuridine)(Purapuridine) is a poisonous alkaloid chemical compound that occurs in plants of the Solanaceae family. Solasodine showed selective cyt...
Pantoprazole
T6928
Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disea...
Barasertib
T14371
AZD1152 is a pro-drug of Barasertib (AZD1152)-hQPA. Which is a highly selective Aurora B inhibitor with IC50 of 0.37 nM in a cell-free assay.
Flurbiprofen
T0291
Flurbiprofen (dl-Flurbiprofen) is an anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption i...
SMIP004
T16901
SMIP004 is an SKP2 E3 ligase inhibitor. SMIP004 is a cancer cell-selective apoptosis inducer of human prostate cancer cells.
Aristolactam I
T3S1227
1.Aristolactam I (Aristololactum) has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway. 2. The effects of Aristolo...
PS-1145
T3094
PS-1145 (IKK Inhibitor X) is a specific IKK inhibitor with IC50 of 88 nM.
SKI V
T8461
SKI V is a potent and noncompetitive non-lipid sphingosine kinase (SPHK; SK) inhibitor (GST-hSK,IC50 : 2 μM), and is a PI3K inhibitor(hPI3k,IC50 : 6 μM), induces...
Brassinolide
T3151
Brassinolide (Brassin lactone) is a plant hormone isolated from rapeseed (Brassica napus) promoting stem elongation and cell division.
Ibandronate sodium monohydrate
T6539
Ibandronate sodium monohydrate (BM-210955) is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis.
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