α-glucosidase — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T41028	α-Glucosidase	α-D-Glucosidase
	α-Glucosidase (α-D-Glucosidase) is a carbohydrate hydrolyzing enzyme that catalyzes the release of α-glucose from the non-reducing end of the substrate. It plays a vital role in facilitating glucose absorption by the sma...
T67898	α-Glucosidase-IN-22		Glucosidase
	α-Glucosidase-IN-22 is a selective inhibitor of α-glucosidase (IC50=0.64 μM). α-Glucosidase-IN-22 has antidiabetic activity and has potential in type 2 diabetes (T2DM) studies.		Glucosidase
T67728	α-Glucosidase-IN-23		Glucosidase
	α-Glucosidase-IN-23 is an orally active α-Glucosidase inhibitor. α-Glucosidase-IN-23 can decrease blood glucose by α-glucosidase inhibition (IC50= 4.48 μM).		Glucosidase
T60715	α-Glucosidase-IN-4		Glucosidase
	α-Glucosidase-IN-4 is a potent α-glucosidase inhibitor with antihypertensive and hypoglycemic activity.		Glucosidase
T7544	Fucoidan		Others
	Fucoidan is found in various species of brown seaweed and algae,with anticancer, antiviral, neuroprotective, immune-modulating.		Others
TN6771	Malabaricone B		Others
	Malabaricone B is a Spice-derived phenolic, it induces mitochondrial damage in lung cancer cells via a p53-independent pathway.		Others
T8319	Butyl isobutyl phthalate	ButylIsobutylPhthalate	Glucosidase
	Butyl isobutyl phthalate (ButylIsobutylPhthalate) is a non-competitive α-glucosidase inhibitor(IC50 :38 μM),it shows a hypoglycemic effect		Glucosidase
TN1990	Norathyriol		Akt , DNA/RNA Synthesis , AMPK , PPAR
	Norathyriol is a potent PTP1B inhibitor with good cell permeability and oral availability.		Akt , DNA/RNA Synthesis , AMPK , PPAR
T61706	α-Amylase/α-Glucosidase-IN-2
	α-Amylase/α-Glucosidase-IN-2 (compound 5) exhibits strong inhibition activity towards both α-amylase and α-glucosidase enzymes, with IC 50 values of 13.02 μM and 13.09 μM, respectively. This compound shows promise for in...
T79225	α-Amylase/α-Glucosidase-IN-3		Glucosidase
	α-Amylase/α-Glucosidase-IN-3 (Compound 17) serves as a dual inhibitor targeting both α-Amylase and α-Glucosidase, exhibiting IC50 values of 0.70 μM and 1.10 μM, respectively. It is applicable for type-II diabetes mellitu...		Glucosidase
T63562	α-Glucosidase-IN-14
	α-Glucosidase-IN-14 is a potent inhibitor of α-glucosidase (IC50: 5.22 μM).
T62222	α-Glucosidase-IN-11
	α-Glucosidase-IN-11 is a highly permeable competitive inhibitor of α-glucosidase (IC50: 0.56 μM). α-Glucosidase-IN-11 binds to the Trp residue in α-glucosidase and has a regulatory effect on protein folding and can be us...
T61519	α-Glucosidase-IN-18
	α-Glucosidase-IN-18 (7B) is an orally active inhibitor of α-glucosidase, displaying an IC 50 value of 3.96 μM. This compound exhibits antidiabetic properties [1].
T61166	α-Glucosidase-IN-16
	α-Glucosidase-IN-16 is a highly effective and orally bioavailable inhibitor of α-glucosidase, displaying a remarkable IC50 value of 3.28 μM. This compound demonstrates the ability to significantly decrease blood glucose ...
T61124	α-Glucosidase-IN-9
	α-Glucosidase-IN-9 (compound 7) is a highly potent α-glucosidase inhibitor with an IC50 of 55.6 μM, making it suitable for type II diabetes research [1].
T60389	α-Glucosidase-IN-5
	α-Glucosidase-IN-5 (compound 8) is isolated from a twig extract of Polyalthia cinnamomea which is a potent α-glucosidase inhibitor with an IC50 of 57.9 µM. α-Glucosidase-IN-5 has the potential for the research of diabete...
T79237	α-Glucosidase-IN-27		Glucosidase
	α-Glucosidase-IN-27 (compound 8l), an α-glucosidase inhibitor with an IC50 value of 25.78 μM, demonstrates potential for research into type 2 diabetes (D2M) [1].		Glucosidase
T78794	α-Glucosidase-IN-31		Glucosidase
	α-Glucosidase-IN-31 (compound R1) is a potent oral α-Glucosidase inhibitor with an IC50 of 10.1 μM, demonstrating significant blood glucose reduction and antidiabetic activity [1].		Glucosidase
T80709	α-Glucosidase-IN-41		Glucosidase
	α-Glucosidase-IN-41 (compound 5o), a potent inhibitor of α-glucosidase, induces alterations in the secondary structure of the enzyme, thereby impeding its catalytic function. This compound is utilized in the study of dia...		Glucosidase
T79700	α-Glucosidase-IN-32		Glucosidase
	α-Glucosidase-IN-32 (compound f26) is a reversible, noncompetitive inhibitor of α-glucosidase that is orally active and exhibits an IC50 of 3.07 μM. It forms a complex with α-glucosidase via hydrogen bonding and hydropho...		Glucosidase