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Search Results for " uricosuric "

10

Compounds

Cat No. Product Name Synonyms Targets
T36125 Tienilic Acid P450
Tienilic Acid is a uricosuric diuretic with certain hepatotoxicity
T0435 Sulfinpyrazone (+/-)-Sulfinpyrazone,G-28315,NSC 75925 COX
Sulfinpyrazone (NSC-75925) is a uricosuric drug that is used to reduce the serum urate levels in gout therapy. It lacks anti-inflammatory, analgesic, and diuretic properties.
T15160 Dotinurad (3,5-dichloro-4-hydroxyphenyl)(1,1-dioxidobenzo[d]thiazol-3(2H)-yl)methanone OAT
Dotinurad ((3,5-dichloro-4-hydroxyphenyl)(1,1-dioxidobenzo[d]thiazol-3(2H)-yl)methanone) is a potent agent of uricosuric (IC50: 3.6 μM for uric acid).
T10632 Bucolome Paramidin,5-Butyl-1-cyclohexylbarbituric acid,Paramidine,Bucolom,Bucolomum P450 , Immunology/Inflammation related
Bucolome (Paramidine) is a CYP2C9 inhibitor with uricosuric and anti-inflammatory activity.
T15251 Etebenecid Urelim Others
Etebenecid (Urelim) is uricosuric agents, which lower uric acid levels in the body by increasing the elimination of uric acid by the kidneys. It also inhibits penicillin tubular secretion.
T0922 Zoxazolamine NSC 24995,Contrazole Others
Zoxazolamine (NSC-24995) is a uricosuric and muscle relaxant. Zoxazolamine acts centrally as a muscle relaxant, but the mechanism of its action is not understood.
T32194 Irtemazole R60844,R-60844,R 60844 Others
Irtemazole (R 60844) is a novel uricosuric substance that is valuable in the treatment of hyperuricemia and gout.
T34469 S 8666 S8666
S 8666 is a potent diuretic with uricosuric action.
T26710 Azapropazone DuP-141,NSC-102824,AHR-3018,AHR 3018,MI-85
Azapropazone is anti-inflammatory agent. Azapropazone has uricosuric properties used to treat rheumatoid arthritis and ankylosing spondylitis. Azapropazone lowered plasma uric acid but exerted only a modest and variable ...
T27275 Epaminurad
Epaminurad (UR-1102) is an orally active, potent and selective URAT1 (urate transporter 1) inhibitor, with a Ki of 0.057 μM. Epaminurad inhibits OAT1 and OAT3 (organic anion transporter) quite modestly. Epaminurad is a u...
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