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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T36125 | Tienilic Acid | P450 | |
Tienilic Acid is a uricosuric diuretic with certain hepatotoxicity | |||
T0435 | Sulfinpyrazone | (+/-)-Sulfinpyrazone,G-28315,NSC 75925 | COX |
Sulfinpyrazone (NSC-75925) is a uricosuric drug that is used to reduce the serum urate levels in gout therapy. It lacks anti-inflammatory, analgesic, and diuretic properties. | |||
T15160 | Dotinurad | (3,5-dichloro-4-hydroxyphenyl)(1,1-dioxidobenzo[d]thiazol-3(2H)-yl)methanone | OAT |
Dotinurad ((3,5-dichloro-4-hydroxyphenyl)(1,1-dioxidobenzo[d]thiazol-3(2H)-yl)methanone) is a potent agent of uricosuric (IC50: 3.6 μM for uric acid). | |||
T10632 | Bucolome | Paramidin,5-Butyl-1-cyclohexylbarbituric acid,Paramidine,Bucolom,Bucolomum | P450 , Immunology/Inflammation related |
Bucolome (Paramidine) is a CYP2C9 inhibitor with uricosuric and anti-inflammatory activity. | |||
T15251 | Etebenecid | Urelim | Others |
Etebenecid (Urelim) is uricosuric agents, which lower uric acid levels in the body by increasing the elimination of uric acid by the kidneys. It also inhibits penicillin tubular secretion. | |||
T0922 | Zoxazolamine | NSC 24995,Contrazole | Others |
Zoxazolamine (NSC-24995) is a uricosuric and muscle relaxant. Zoxazolamine acts centrally as a muscle relaxant, but the mechanism of its action is not understood. | |||
T32194 | Irtemazole | R60844,R-60844,R 60844 | Others |
Irtemazole (R 60844) is a novel uricosuric substance that is valuable in the treatment of hyperuricemia and gout. | |||
T34469 | S 8666 | S8666 | |
S 8666 is a potent diuretic with uricosuric action. | |||
T26710 | Azapropazone | DuP-141,NSC-102824,AHR-3018,AHR 3018,MI-85 | |
Azapropazone is anti-inflammatory agent. Azapropazone has uricosuric properties used to treat rheumatoid arthritis and ankylosing spondylitis. Azapropazone lowered plasma uric acid but exerted only a modest and variable ... | |||
T27275 | Epaminurad | ||
Epaminurad (UR-1102) is an orally active, potent and selective URAT1 (urate transporter 1) inhibitor, with a Ki of 0.057 μM. Epaminurad inhibits OAT1 and OAT3 (organic anion transporter) quite modestly. Epaminurad is a u... |