spike — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T36654	Anti-SARS-CoV-2 Spike mAb (CR3022)	Anti-SARS-CoV-2 Spike mAb (CR3022)
	Anti-SARS-CoV-2 Spike mAb (CR3022) is a human monoclonal IgG1 antibody derived from CHO cells. It specifically targets the S1 domain of the Spike protein in both SARS-CoV and SARS-CoV-2.
T36655	Anti-Spike-RBD mAb
	Anti-Spike-RBD mAb is a CHO cell derived human monoclonal IgG1 antibody. Blocking the interaction of spike protein and ACE2 is a potential therapeutic approach for SARS-CoV-2 treatment[1]. [1]. Chunyan Wang, et al. A Hum...
T36656	Anti-Spike-RBD Single Domain mAb
	The Anti-Spike-RBD Single Domain mAb is a monoclonal antibody derived from CHO cells in Alpaca. It is composed of VHH-huFc and exhibits a strong affinity for the SARS-CoV-2 RBD. [1]
T83742	SBP1 TFA	Spike Binding Peptide 1
	Spike Binding Peptide 1 (SBP1), representing amino acids 21-43 of angiotensin-converting enzyme 2 (ACE2), has been utilized in a novel approach involving lipid nanoparticles (LNPs) encapsulated with oseltamivir phosphate...
T9109	SSAA09E2		RAAS , SARS-CoV
	SSAA09E2 is a new SARS-CoV replication inhibitor, acting by blocking early interactions of SARS-S with the receptor for SARS-CoV, Angiotensin Converting Enzyme-2 (ACE2).		RAAS , SARS-CoV
T83737	LRRKtide TFA	Moesin (550-564),Membrane-organizing Extension Spike Protein (550-564)
	LRRKtide, a peptide substrate for leucine-rich repeat kinase 2 (LRRK2)—an enzyme often mutated in Parkinson's disease patients—corresponds to amino acids 550-564 of the membrane-organizing extension spike protein (moesin...
T75116	COVID-19 Spike Protein mRNA-LNP
	COVID-19 Spike Protein mRNA-LNP is a lipid nanoparticle (LNP) formulated with the novel coronavirus pneumonia spike protein, positioned on the membrane surface, designed for applications such as RNA delivery, translation...
T75102	COVID-19 Spike Protein mRNA(N1-Me-Pseudo UTP)
	The COVID-19 Spike Protein mRNA, responsible for expressing the COVID-19 spike protein, is crucial for evaluating RNA delivery, translation efficiency, and cell viability. Positioned on the membrane surface, this spike p...
T2869	Emodin	Frangula emodin	SARS-CoV , Casein Kinase , Autophagy
	Emodin (Frangula emodin) is a naturally occurring anthraquinone present in the roots and barks of numerous plants; exerts antiproliferative effects in Y cells that are regulated by different signaling pathways.		SARS-CoV , Casein Kinase , Autophagy
T15271	Denifanstat	FASN-IN-2,TVB2640,TVB-2640	Fatty Acid Synthase
	Denifanstat (FASN-IN-2) is a Fatty Acid Synthase (FASN) inhibitor(IC50 of 0.052 μM and an EC50 of 0.072 μM),with potential antineoplastic activity.		Fatty Acid Synthase
T78704	PLpro/RBD-IN-1		SARS-CoV
	PLpro/RBD-IN-1 (Compound 5) serves as a dual inhibitor targeting both the SARS-CoV-2 papain-like protease (PLpro) and the receptor-binding domain (RBD) of the spike protein, exhibiting half-maximal inhibitory concentrati...		SARS-CoV
T37424	CAY10781	CAY10781	Others
	CAY10781 is an inhibitor of the protein-protein interaction between neuropilin-1 (NRP-1) and VEGF-A.1It inhibits the interaction by 43% when used at a concentration of 12.5 μM. CAY10781 also inhibits VEGF-A-induced phosp...		Others
T26359	AA 497 (Free Base)	AA-497,AA 497,AA497
	AA 497, a beta-2 agonist, causes relaxation and suppresses Ca spike frequency.
T69252	CPD26
	CPD26 is a novel non-RBD binding modulator to inhibit SARS-CoV-2 by prohibiting the conformational change of the spike (S) protein.
T68310	CPD7
	CPD7 is a novel non-RBD binding modulator to inhibit SARS-CoV-2 by prohibiting the conformational change of the spike (S) protein.
T70836	DMJ-I-228
	DMJ-I-228 is a specific inhibitor of HIV-1 entry through interaction with the Env spike by virtue of the incorporation of a guandinium group.
T80581	Plutavimab	COVI-AMG,STI-2020	SARS-CoV
	Plutavimab is a humanized IgG1-κ monoclonal antibody targeting the receptor binding domain (RBD) of the SARS-CoV-2 spike (S) glycoprotein [1] [2].		SARS-CoV
T71989	CPD7 HCl
	CPD7 HCl is a novel non-RBD binding modulator to inhibit SARS-CoV-2 by prohibiting the conformational change of the spike (S) protein.
T36876	SBP1
	Human ACE2 receptor-derived 23-amino acid peptide. Binds receptor binding domain (RBD) of insect-derived SARS-CoV-2 spike protein (KD = 1.3 μM for N-terminal biotinylated, insect-derived spike protein RBD; see Zhang et a...
T36877	SBP1-FITC	SBP1-FITC
	Fluorescently labelled peptide derived from human ACE2 (SBP1, Cat. No. 7233). Composed of SBP1 conjugated to FITC (Fluorescein-5-isothiocyanate; Cat. No. 5440). SBP1 binds receptor binding domain (RBD) of insect-derived ...