sclerostin — TargetMol Chemicals

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Search Results for " sclerostin "

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Compounds

Recombinant Proteins

Cat No.	Product Name	Synonyms
T69486	BMD4503-2
	BMD4503-2 is an LRP5/6-sclerostin interaction inhibitor. BMD4503-2 recovers the downregulated activity of the Wnt/β-catenin signaling pathway by competitively binding to the LRP5/6-sclerostin complex.
T78278	Blosozumab
	Blosozumab (LY2541546), an anti-sclerostin (SOST) antibody, promotes bone formation while decreasing bone resorption, with potential applications in osteoporosis research [1] [2].
T81173	Setrusumab	BPS 804
	Setrusumab (BPS 804) is a fully humanized monoclonal antibody targeting sclerostin, effectively enhancing bone strength. It is utilized in research on Osteogenesis Imperfecta (OI) and cancer [1].

Compounds

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-01633	SOST Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	SOST Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23 kDa and the accession number is A6HJF6.
TMPY-00925	SOST Protein, Human, Recombinant (His)	Human	HEK293 Cells
	SOST Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.5 kDa and the accession number is Q9BQB4-1.
TMPJ-01294	SOST Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Sclerostin (SOST) is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. Cerberus/DAN family members are putative BMP antagonists, and include Dan, Cerberus, Gre...
TMPY-05113	SOST Protein, Human, Recombinant (His), Biotinylated	Human	HEK293 Cells
	SOST Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.5 kDa and the accession number is Q9BQB4-1.
TMPK-01293	SOST Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	SOST, also known as sclerostin, is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. SOST is negative regulator of bone growth that acts through inhibition of ...
TMPK-00102	SOST Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	SOST, also known as sclerostin, is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. SOST is negative regulator of bone growth that acts through inhibition of ...
TMPK-00103	SOST Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	SOST, also known as sclerostin, is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. SOST is negative regulator of bone growth that acts through inhibition of ...
TMPK-00740	LRP-5 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	A role for low-density lipoprotein-related receptor 5 (LRP5) in human bone was first established by the identification of genetic alterations that led to dramatic changes in bone mass. Shortly thereafter, mutations that ...
TMPK-00739	LRP-5 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	A role for low-density lipoprotein-related receptor 5 (LRP5) in human bone was first established by the identification of genetic alterations that led to dramatic changes in bone mass. Shortly thereafter, mutations that ...