pumps — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T16339	Norverapamil hydrochloride	(±)-Norverapamil hydrochloride,D591 hydrochloride	Calcium Channel , P-gp , Drug Metabolite
	Norverapamil hydrochloride (D591 hydrochloride) ((±)-Norverapamil hydrochloride) is an N-demethylated metabolite of Verapamil and it is an L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor.		Calcium Channel , P-gp , Drug Metabolite
TP1911L	CALP3 acetate(261969-05-5 free base)		Calcium Channel
	CALP3 acetate is a potent Ca2+ channel blocker that activates EF hand motifs of Ca2+-binding proteins. CALP3 acetate can functionally mimic increased [Ca2+]i by modulating the activity of Calmodulin (CaM), Ca2+ channels ...		Calcium Channel
T20714	Levolansoprazole	(S)-Lansoprazole,(-)-Lansoprazole	Proton pump
	Levolansoprazole ((S)-Lansoprazole), a proton pump inhibitor, irreversibly inhibits H+/K+-stimulated ATPase pumps in parietal cells (IC50: 5.2 μM). It also inhibits acid formation in isolated canine parietal cells (IC50:...		Proton pump
T24005	DJ101	DJ-101,DJ 101
	DJ101is an effective and metabolically stable inhibitor of tubulin. It can circumvent the drug efflux pumps responsible for multidrug resistance of existing tubulin inhibitors.
T26911	Bromotetrandrine	5-Bromotetrandrine,W-198,BrTet,W 198,W198
	Bromotetrandrine is an P-glycoprotein inhibitor, which were developed and coadministered with chemotherapeutic drugs to overcome the effect of efflux pumps thus enhancing the chemosensitivity of therapeutics.
T80247	Caloxin 3A1		Calcium Channel
	Caloxin 3A1, a biologically active peptide, is a member of the caloxins, which are inhibitors of the extracellular plasma membrane (PM) Ca2+ pumps. Specifically, it inhibits plasma membrane calcium pumps (PMCAs) without ...		Calcium Channel
TP2170	CALP3 TFA（261969-05-5 free base)	CALP3 TFA	Calcium Channel
	CALP3 TFA is a potent Ca2+ channel blocker that activates EF-hand motifs of Ca2+-binding proteins. It can functionally mimic increased [Ca2+]i by modulating the activity of Calmodulin, Ca2+ channels, and pumps.		Calcium Channel
T40526	ATP dipotassium	Adenosine5'-triphosphatedipotassium
	ATP dipotassium (Adenosine 5'-triphosphate dipotassium) is a vital compound involved in energy storage and metabolism within living organisms. It plays a crucial role in supplying metabolic energy for driving pumps and a...
T14293	Annonacin		Others
	Annonacin is an Acetogenin and promotes cytotoxicity via a pathway inhibiting the mitochondrial complex and it is the active agent found in Graviola leaf extract to act as an inhibitor of sodium/potassium (NKA) and sarco...		Others
T75372	BODIPY FL Thapsigargin
	BODIPY FL Thapsigargin, a potent green fluorescent dye, effectively inhibits intracellular SERCA-type Ca 2+ pumps localized in the sarcoplasmic/endoplasmic reticulum. It is utilized to investigate thapsigargin binding si...
T36810	UPSEM 792 hydrochloride
	Ultrapotent PSEM (uPSEM) agonist for PSAM4-GlyR and PSAM4-5HT3 (Ki = 0.7 nM for PSAM4-GlyR and <10 nM for PSAM4-5HT3). Exhibits >10,000-fold agonist selectivity for PSAM4-GlyR over α7-GlyR, α7-5HT3, and 5HT3-R, and 230-f...
T75326	ATP ditromethamine
	ATP ditromethamine (Adenosine 5'-triphosphate ditromethamine), a vital in vivo energy storage and metabolic constituent, fuels metabolic pumps and acts as a cellular coenzyme. It also plays a crucial role as an endogenou...
T75325	ATP dimagnesium
	Adenosine 5'-triphosphate (ATP) dimagnesium, a pivotal molecule in energy storage and metabolism, fuels metabolic pumps and acts as a coenzyme within cells. Additionally, it plays a significant role as an endogenous sign...
TN5530	Volkensiflavone	Talbotaflavone	Others
	Volkensiflavone (Talbotaflavone) is a natural product found in astragalus and garcinia. It has the function of plant metabolite, is a secondary metabolic product. Volkensiflavone is a biflavonoid belonging to the hydroxy...		Others
T75789	CALP3 TFA
	CALP3 TFA, a Ca2+-like peptide and potent Ca2+ channel blocker, activates EF hand motifs in Ca2+-binding proteins. It can mimic increased [Ca2+]i, modulating the activity of Calmodulin (CaM), Ca2+ channels, and pumps. Th...
T68480	4SC-207
	4SC-207 is a novel microtubule inhibitor , which shows strong anti-proliferative activity in a large panel of tumor cell lines with an average GI50 of 11 nM. In particular, 4SC-207 is active in multi-drug resistant cell ...
T35902	Milbemycin A4 oxime
	Milbemycin A4 oxime is a derivative of milbemycin A4 and a component of milbemycin oxime , compounds that both have insecticidal and nematocidal activity. Milbemycin A4 oxime (0.05 mg/kg) reduces the number of microfilar...
T37743	N-octadecanoyl-L-Homoserine lactone
	Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm forma...
T37741	N-hexadecanoyl-L-Homoserine lactone	C16-HSL,N-palmitoyl-L-Homoserine,N-hexadecanoyl-L-Homoserine lactone
	Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density.[1] This regulatory process manifests itself with a variety of phenotypes including biofilm fo...