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Search Results for " protease-activated "

20

Compounds

Cat No. Product Name Synonyms Targets
T7740 Protease-Activated Receptor-4 diTFA Protease-Activated Receptor-4 diTFA(245443-52-1(free base)) Protease-activated Receptor
Protease-Activated Receptor-4 diTFA,2454 is the proteinase-activated receptor-4 (PAR4)agonist
T38836L Protease-Activated Receptor-1, PAR-1 Agonist acetate Protease-activated Receptor
Protease-Activated Receptor-1, PAR-1 Agonist acetate is a selective proteinase-activated receptor1 (PAR-1) agonist peptide. Protease-Activated Receptor-1, PAR-1 Agonist acetate corresponds to PAR1 tethered ligand and whi...
T7513 Protease-Activated Receptor-2, amide SLIGKV-NH2 Protease-activated Receptor
Protease-Activated Receptor-2, amide (SLIGKV-NH2) is an agonist of PAR2 (IC50 : 10.4 M)
T38836 Protease-Activated Receptor-1, PAR-1 Agonist
Protease-Activated Receptor-1 (PAR-1) Agonist, a selective peptide, activates the PAR-1 receptor by mimicking the specific actions of thrombin. It corresponds to the PAR1 tethered ligand, facilitating selective activatio...
T7380 Protease-Activated Receptor-4 Protease-activated Receptor
Protease-Activated Receptor-4 is the proteinase-activated receptor-4 (PAR4) agonist, with Antiplatelet Therapy
T36288 Protease-Activated Receptor-1, PAR-1 Agonist TFA
Protease-Activated Receptor-1 (PAR-1) Agonist TFA is a selective peptide that acts as an agonist for the proteinase-activated receptor-1 (PAR-1). Corresponding to the tethered ligand of PAR-1, this compound mimics the ac...
T36289 Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA
Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA is a peptide that acts as an agonist for the proteinase-activated receptor (PAR-3)[1].
TP1046 SLIGRL-NH2 Protease-Activated Receptor-2 Activating Peptide Protease-activated Receptor
SLIGRL-NH2 (Protease-Activated Receptor-2 Activating Peptide) is a protease-activated receptor-2 (PAR-2) agonist that induces non-histaminergic pruritus.
T36286 Protease-Activated Receptor-3 (PAR-3) (1-6), human
TFRGAP-amide, human PAR-3-derived tethered ligand sequence which does not activate PAR-3 but rather activates PAR-1 and PAR-2, either in Jurkat or in other PAR-expressing cells.
T1986L Atopaxar Hydrobromide Protease-activated Receptor
Atopaxar, a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling. Atopaxar has been investigated for the treatment of Coronary Artery Disease and Acute Coronary Syndrome.
T1893 Parmodulin 2 ML 161 Protease-activated Receptor
Parmodulin 2 (ML 161) is the inhibitor of protease-activated receptor 1 (PAR1)-mediated platelet activation (IC50: 0.26 μM for the inhibition of platelet P-selectin expression on human platelets). It also inhibits thromb...
TQ0012 AZ3451 Protease-activated Receptor
AZ3451 is an allosteric antagonist of protease-activated receptor-2 (PAR2, IC50: 23 nM).
T7137 I-191 Protease-activated Receptor
I-191 is a potent antagonist of protease-activated receptor 2 (PAR2), inhibits multiple signaling functions in human cancer cells.
T1986 Atopaxar E5555,ER-172594-00 Protease-activated Receptor
Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling. Atopaxar has been investigated for the treatment of Coronary Artery Disease and Acute Coronary Syndrome.
T64285 Protease-Activated Receptor-1 antagonist 2
Protease-Activated Receptor-1 antagonist 2 is a selective, orally active protease-activated receptor-1 (PAR-1) antagonist (IC50: 7 nM). It has shown good pharmacokinetic properties and can be used for studies related to ...
T62507 Protease-Activated Receptor-1 antagonist 1
Protease-Activated Receptor-1 antagonist 1 (Compound 13) is a protease-activated receptor 1 (PAR-1) antagonist with an IC50 of 3 nM obtained by the FLIPR technique. antagonist 1 can be used to study thrombotic cardiovasc...
T63382 Protease-Activated Receptor-1 antagonist 3
Protease-Activated Receptor-1 antagonist 3 is a potent antagonist (IC50: 7 nM) of Protease-Activated Receptor 1protease-activated receptor-1. antagonist 3 exhibits binding affinity to hERG K+ channels (IC50: 9 μM).
T74266 Protease-Activated Receptor-1 antagonist 2
Protease-Activated Receptor-1 Antagonist 2 is an orally active antagonist of protease-activated receptor-1 (PAR-1), demonstrating significant potency with an IC 50 of 7 nM. It exhibits favorable pharmacokinetic character...
TP1046L PAR-2 Activating Peptide acetate SLIGRL-NH2 acetate,PAR-2 Activating Peptide acetate(171436-38-7 free base),Protease-Activated Receptor-2 Activating Peptide acetate Protease-activated Receptor
PAR-2 Activating Peptide acetate (SLIGRL-NH2 acetate) is an agonist of Protease-Activated Receptor-2 (PAR-2).
T2370 AC-55541 AOB2796 Proteasome , Protease-activated Receptor
AC-55541 (AOB2796) is a novel PAR2 agonist; activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays, with potencies ranging from 200 to 1000 nM.

Compounds

Protease-Activated Receptor-4 diTFA
T7740
Synonym: Protease-Activated Receptor-4 diTFA(245443-52-1(free base))
Target: Protease-activated Receptor
Protease-Activated Receptor-1, PAR-1 Agonist acetate
T38836L
Synonym:
Target: Protease-activated Receptor
Protease-Activated Receptor-2, amide
T7513
Synonym: SLIGKV-NH2
Target: Protease-activated Receptor
Protease-Activated Receptor-1, PAR-1 Agonist
T38836
Synonym:
Target:
Protease-Activated Receptor-4
T7380
Synonym:
Target: Protease-activated Receptor
Protease-Activated Receptor-1, PAR-1 Agonist TFA
T36288
Synonym:
Target:
Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA
T36289
Synonym:
Target:
SLIGRL-NH2
TP1046
Synonym: Protease-Activated Receptor-2 Activating Peptide
Target: Protease-activated Receptor
Protease-Activated Receptor-3 (PAR-3) (1-6), human
T36286
Synonym:
Target:
Atopaxar Hydrobromide
T1986L
Synonym:
Target: Protease-activated Receptor
Parmodulin 2
T1893
Synonym: ML 161
Target: Protease-activated Receptor
AZ3451
TQ0012
Synonym:
Target: Protease-activated Receptor
I-191
T7137
Synonym:
Target: Protease-activated Receptor
Atopaxar
T1986
Synonym: E5555,ER-172594-00
Target: Protease-activated Receptor
Protease-Activated Receptor-1 antagonist 2
T64285
Synonym:
Target:
Protease-Activated Receptor-1 antagonist 1
T62507
Synonym:
Target:
Protease-Activated Receptor-1 antagonist 3
T63382
Synonym:
Target:
Protease-Activated Receptor-1 antagonist 2
T74266
Synonym:
Target:
PAR-2 Activating Peptide acetate
TP1046L
Synonym: SLIGRL-NH2 acetate,PAR-2 Activating Peptide acetate(171436-38-7 free base),Protease-Activated Receptor-2 Activating Peptide acetate
Target: Protease-activated Receptor
AC-55541
T2370
Synonym: AOB2796
Target: Proteasome, Protease-activated Receptor
1 2 3 4
TargetMol