p75ntr — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T16766	Ro 08-2750
	Ro 08-2750 is a non-peptide and reversible nerve growth factor (NGF) inhibitor which binds to NGF, and with an IC50 of ~ 1 µM. Ro 08-2750 is a selective MSI RNA-binding activity inhibitor, with an IC50 of 2.7 μM. Ro 08-2...
T11861	LM11A-31 dihydrochloride		Others
	LM11A-31 dihydrochloride is a water-soluble, non-peptide with high blood-brain barrier permeability.LM11A-31 dihydrochloride, a p75NTR (neurotrophin receptor p75) Ligand, is a potent proNGF (nerve growth factor) antagoni...		Others
T12384	PD 90780		Others
	PD 90780 is a non peptide antagonist of nerve growth factor (NGF). PD 90780 interacts with NGF, prevents NGF binds with p75NTR. PD 90780 inhibits NGF-p75NTR interaction with IC50s of 23.1 and 1.8 µM in PC12 cells and PC1...		Others
T28206	NSC49652	NSC 49652,NSC-49652	Apoptosis
	NSC49652 triggers apoptotic cell death dependent on p75NTR and JNK activity in neurons and melanoma cells, and inhibits tumor growth in a melanoma mouse model.		Apoptosis
TP2278	NTR 368		Others
	cytoplasmic peptide of the neurotrophin receptor p75NTR		Others
T75831	NTR 368 TFA
	NTR 368 TFA, a peptide derived from the p75 neurotrophin receptor (p75NTR) and corresponding to residues 368-381 of the human receptor, exhibits a helix-forming propensity in the presence of micellar lipid. It is a poten...
T76813	Bedinvetmab
	Bedinvetmab (ZTS-00508841), a canine monoclonal antibody (mAb) designed to target nerve growth factor (NGF), prevents NGF from interacting with its receptors, tropomyosin receptor kinase A (trkA) and p75 neurotrophin rec...
T35365	LM11A-31	LM11A-31	Others
	LM11A-31 is a useful organic compound for research related to life sciences. The catalog number is T35365 and the CAS number is 289475-77-0.		Others
T74097	THX-B
	THX-B, a potent non-peptidic antagonist of the neurotrophin receptor p75 (p75 NTR), is utilized in the study of diabetic kidney disease, neurodegenerative, and inflammatory disorders [1] [2] [3].

Compounds

Ro 08-2750

T16766

Synonym:

Target:

LM11A-31 dihydrochloride

Synonym: NSC 49652,NSC-49652

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-02614	NGFR/p75NTR Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	NGFR/p75NTR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.6 kDa and the accession number is P08138.
TMPY-02588	NGFR/p75NTR Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	NGFR/p75NTR Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.6 kDa and the accession number is Q9Z0W1.
TMPY-02541	NGFR/p75NTR Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	NGFR/p75NTR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is Q9Z0W1.
TMPY-02615	NGFR/p75NTR Protein, Human, Recombinant (His)	Human	HEK293 Cells
	NGFR/p75NTR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is P08138.
TMPY-04831	NGFR/p75NTR Protein, Rabbit, Recombinant (hFc)	Rabbit	HEK293 Cells
	NGFR/p75NTR Protein, Rabbit, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.1 kDa and the accession number is XP_008269543.1.
TMPY-06973	NGFR/p75NTR Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	NGFR/p75NTR Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.03 kDa and the accession number is XP_005583674.1.
TMPY-04646	NGFR/p75NTR Protein, Rabbit, Recombinant (His)	Rabbit	HEK293 Cells
	NGFR/p75NTR Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.8 kDa and the accession number is XP_008269543.1.
TMPY-06959	NGFR/p75NTR Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	NGFR/p75NTR Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.34 kDa and the accession number is P07174.
TMPJ-01468	Pro-Beta NGF Protein, Human, Recombinant	Human	E. coli
	The precursor form of the nerve growth factor (proNGF) like its mature form is characterized by the cystin knot motif consisting of three cystine bridges, whereas proneurotrophins and mature neurotrophins elicit opposite...
TMPH-03219	Rabies virus (RABV) (strain India) Glycoprotein (His)	RABV	P. pastoris (Yeast)
	Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell memb...
TMPJ-00134	Pro-BDNF Protein, Human, Recombinant	Human	E. coli
	The precursor form of Brain-Derived Neurotrophic Factor (pro-BDNF) interacts preferentially with the pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin and induces neuronal apoptosis, w...
TMPH-03223	Rabies virus (RABV) (strain HEP-Flury) Glycoprotein (His)	RABV	Baculovirus Insect Cells
	Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell memb...
TMPH-03220	Rabies virus (RABV) (strain India) Glycoprotein (His & SUMO)	RABV	E. coli
	Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell memb...
TMPH-03221	Rabies virus (RABV) (strain CVS-11) Glycoprotein (His & Myc & SUMO)	RABV	E. coli
	Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell memb...
TMPH-03222	Rabies virus (RABV) (strain ERA) Glycoprotein (His)	RABV	E. coli
	Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell memb...
TMPH-03224	Rabies virus (RABV) (strain HEP-Flury) Glycoprotein (E. coli, His)	RABV	E. coli
	Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell memb...