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Search Results for " intercalator "

20

Compounds

Cat No. Product Name Synonyms Targets
T15507 Hycanthone Etrenol(mesylate),Win 249-33 DNA/RNA Synthesis , Topoisomerase , Parasite
Hycanthone (Etrenol(mesylate)) is a potent drug of antischistosomal. Hycanthone is a DNA intercalator that inhibits RNA synthesis and DNA topoisomerases I and II. Hycanthone inhibits nucleic acid biosynthesis and inhibit...
T2394 Pixantrone dimaleate BBR-2778,Pixantrone Maleate,BBR 2778 dimaleate Topoisomerase
Pixantrone dimaleate (Pixantrone Maleate) (BBR 2778 dimaleate) is an experimental antineoplastic drug.
T11872L LMP744 hydrochloride NSC706744 hydrochloride,MJ-III65 hydrochloride Topoisomerase
LMP744 hydrochloride (NSC-706744 hydrochloride) is a DNA intercalator and Topoisomerase I (Top1) inhibitor with antitumor activity. 
T1767 BMH-21 BMH21 DNA/RNA Synthesis
BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.
T30425 BePI Be-PI,NSC 664711,NSC-664711,NSC664711,Be PI
BePI can be a specific intercalator of both double and triple-helical DNA.
T11872 LMP744 NSC706744,MJ-III65 Others
LMP744 is a DNA intercalator and Topoisomerase I (Top1) inhibitor with antitumor activity.
T27085 Crisnatol mesylate BW-A-770U mesylate,BW-A-770U,BW-77OU-82,770U-82,770U-82 mesylate,BW-770
Crisnatol, a potent and selective DNA intercalator, has potential anticancer activity.
T23750 AQ4 AQ-4,AQ 4
AQ4 is an inhibitor of topoisomerase II. It is also a DNA intercalator.
T61351 Pixantrone hydrochloride
Pixantrone (BBR 2778 (free base)) hydrochloride is a mitoxantrone analog compound that acts as a topoisomerase II inhibitor and DNA intercalator. It displays anti-tumor activity [1] [2].
T25159 Bisnafide DMP 840
Bisnafide is a Naphthalimide Analogue that acts as a DNA intercalator and topo II inhibitor. It is also an antiangiogenic agent that can normalize tumor vessels and promote the delivery of cytotoxic agents to tumor sites...
T23817 BPTQ B-P-T-Q
BPTQ is a typical intercalator of DNA that acts by inducing a dose-dependent inhibitory effect on the proliferation of cancer cells by arresting cells at the S and G2/M phase.
T69245 Amikhelline
Amikhelline is an antimitotic drug. It acts as a DNA intercalator and inhibits DNA polymerase.
T18737 AcLysValCit-PABC-DMAE-SW-163D Others
AcLysValCit-PABC-DMAE-SW-163D is a drug-linker conjugate for antibody-drug conjugates (ADCs), featuring a natural bis-intercalator, SW-163D, attached through an AcLysValCitPABC-DMAE linker[1].
T4047L Bisantrene HCl CL216942,CL-216942,NSC-337766,CL 216942
Bisantrene (CL-216942; NSC 337766) is a topoisomerase II poison and DNA intercalator. It can be used as a Rac1 inhibitor or model compound to study P-glycoprotein-mediated multi-drug resistance (MDR1). Bisantrene inserts...
T60900 Pixantrone
Pixantrone has anti-tumor activity that is a DNA intercalator and topoisomerase II inhibitor.
T70609 Bisnafide mesylate
Bisnafide is a Naphthalimide Analogue that acts as DNA intercalator and topo II inhibitor. It is also an antiangiogenic agent. Antiangiogenic agents can normalize tumor vessels and promote the delivery of cytotoxic agent...
T39548 Amustaline dihydrochloride S-303 dihydrochloride
Amustaline (S-303) dihydrochloride is a nucleic acid-targeted alkylator recognized for its efficacy as a pathogen inactivation agent in blood components containing red blood cells. This compound comprises three key eleme...
T73217 Crisnatol BWA770U
Crisnatol (BWA770U), an arylmethylaminopropanediol class DNA intercalator, serves as an orally active anticancer agent. It demonstrates in vitro cytotoxicity specifically against human breast cancer cells, while sparing ...
T36181 Quinaldopeptin
Quinaldopeptin is a quinomycin antibiotic. It is active against a variety of bacteria, including S. pyogenes, S. aureus, C. perfringens, S. faecalis, E. coli, and K. pneumoniae (MICs = 0.2, 0.4, 0.8, 1.6, 3.1 and 6.3 μg/...
T36096 Thiocoraline
Thiocoraline is a depsipeptide and DNAbis-intercalator originally isolated fromMicromonosporawith antibacterial and anticancer activities.1,2It is active against the Gram-positive bacteriaS. aureus,B. subtilis, andM. lut...
TargetMol