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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T15507 | Hycanthone | Etrenol(mesylate),Win 249-33 | DNA/RNA Synthesis , Topoisomerase , Parasite |
Hycanthone (Etrenol(mesylate)) is a potent drug of antischistosomal. Hycanthone is a DNA intercalator that inhibits RNA synthesis and DNA topoisomerases I and II. Hycanthone inhibits nucleic acid biosynthesis and inhibit... | |||
T2394 | Pixantrone dimaleate | BBR-2778,Pixantrone Maleate,BBR 2778 dimaleate | Topoisomerase |
Pixantrone dimaleate (Pixantrone Maleate) (BBR 2778 dimaleate) is an experimental antineoplastic drug. | |||
T11872L | LMP744 hydrochloride | NSC706744 hydrochloride,MJ-III65 hydrochloride | Topoisomerase |
LMP744 hydrochloride (NSC-706744 hydrochloride) is a DNA intercalator and Topoisomerase I (Top1) inhibitor with antitumor activity. | |||
T1767 | BMH-21 | BMH21 | DNA/RNA Synthesis |
BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX. | |||
T30425 | BePI | Be-PI,NSC 664711,NSC-664711,NSC664711,Be PI | |
BePI can be a specific intercalator of both double and triple-helical DNA. | |||
T11872 | LMP744 | NSC706744,MJ-III65 | Others |
LMP744 is a DNA intercalator and Topoisomerase I (Top1) inhibitor with antitumor activity. | |||
T27085 | Crisnatol mesylate | BW-A-770U mesylate,BW-A-770U,BW-77OU-82,770U-82,770U-82 mesylate,BW-770 | |
Crisnatol, a potent and selective DNA intercalator, has potential anticancer activity. | |||
T23750 | AQ4 | AQ-4,AQ 4 | |
AQ4 is an inhibitor of topoisomerase II. It is also a DNA intercalator. | |||
T61351 | Pixantrone hydrochloride | ||
Pixantrone (BBR 2778 (free base)) hydrochloride is a mitoxantrone analog compound that acts as a topoisomerase II inhibitor and DNA intercalator. It displays anti-tumor activity [1] [2]. | |||
T25159 | Bisnafide | DMP 840 | |
Bisnafide is a Naphthalimide Analogue that acts as a DNA intercalator and topo II inhibitor. It is also an antiangiogenic agent that can normalize tumor vessels and promote the delivery of cytotoxic agents to tumor sites... | |||
T23817 | BPTQ | B-P-T-Q | |
BPTQ is a typical intercalator of DNA that acts by inducing a dose-dependent inhibitory effect on the proliferation of cancer cells by arresting cells at the S and G2/M phase. | |||
T69245 | Amikhelline | ||
Amikhelline is an antimitotic drug. It acts as a DNA intercalator and inhibits DNA polymerase. | |||
T18737 | AcLysValCit-PABC-DMAE-SW-163D | Others | |
AcLysValCit-PABC-DMAE-SW-163D is a drug-linker conjugate for antibody-drug conjugates (ADCs), featuring a natural bis-intercalator, SW-163D, attached through an AcLysValCitPABC-DMAE linker[1]. | |||
T4047L | Bisantrene HCl | CL216942,CL-216942,NSC-337766,CL 216942 | |
Bisantrene (CL-216942; NSC 337766) is a topoisomerase II poison and DNA intercalator. It can be used as a Rac1 inhibitor or model compound to study P-glycoprotein-mediated multi-drug resistance (MDR1). Bisantrene inserts... | |||
T60900 | Pixantrone | ||
Pixantrone has anti-tumor activity that is a DNA intercalator and topoisomerase II inhibitor. | |||
T70609 | Bisnafide mesylate | ||
Bisnafide is a Naphthalimide Analogue that acts as DNA intercalator and topo II inhibitor. It is also an antiangiogenic agent. Antiangiogenic agents can normalize tumor vessels and promote the delivery of cytotoxic agent... | |||
T39548 | Amustaline dihydrochloride | S-303 dihydrochloride | |
Amustaline (S-303) dihydrochloride is a nucleic acid-targeted alkylator recognized for its efficacy as a pathogen inactivation agent in blood components containing red blood cells. This compound comprises three key eleme... | |||
T73217 | Crisnatol | BWA770U | |
Crisnatol (BWA770U), an arylmethylaminopropanediol class DNA intercalator, serves as an orally active anticancer agent. It demonstrates in vitro cytotoxicity specifically against human breast cancer cells, while sparing ... | |||
T36181 | Quinaldopeptin | ||
Quinaldopeptin is a quinomycin antibiotic. It is active against a variety of bacteria, including S. pyogenes, S. aureus, C. perfringens, S. faecalis, E. coli, and K. pneumoniae (MICs = 0.2, 0.4, 0.8, 1.6, 3.1 and 6.3 μg/... | |||
T36096 | Thiocoraline | ||
Thiocoraline is a depsipeptide and DNAbis-intercalator originally isolated fromMicromonosporawith antibacterial and anticancer activities.1,2It is active against the Gram-positive bacteriaS. aureus,B. subtilis, andM. lut... |