Home Tools
Log in
Cart

Search Result

Search Results for " heterobifunctional "

20

Compounds

Cat No. Product Name Synonyms Targets
T9370 DCBP-1 Epigenetic Reader Domain , Ligand for E3 Ligase
dCBP-1 is a chemical degrader of p300/CBP. dCBP-1 hijacks the E3 ubiquitin ligase CRBN for selective degradation of p300/CBP. Degradation of p300/CBP by dCBP-1 leads to effective multiple myeloma cell killing.
T9116 SMCC N-Succinimidyl 4-(N-maleimidomethyl)cycl Others
SMCC (N-Succinimidyl 4-(N-maleimidomethyl)cycl) is a heterobifunctional protein crosslinker.
T8667 MC-Gly-Gly-Phe-Gly DSN28369 Others
MC-Gly-Gly-Phe-Gly (DSN28369) is a heterobifunctional linker, and useful to make antibody drug conjuate (ADC).
T14061 EMCS 6-Maleimidohexanoic acid N-hydroxysuccinimide ester Others
EMCS (6-Maleimidohexanoic acid N-hydroxysuccinimide ester) is a heterobifunctional crosslinking agent, which is a compound for the preparation of hapten conjugate and enzyme immune conjugate, and an effective protective ...
T17389 AMAS Others
AMAS is a non-claevable heterobifunctional crosslinker with NHS ester and maleimide groups that enables covalent conjugation of amine- and sulfhydryl-containing molecules.
T5440 Dbet57 Epigenetic Reader Domain
dBET57 is heterobifunctional degrader of BRD4 based on the PROTAC technology, exhibits significant degradation of BRD4BD1 with a DC50/5h of 500 nM ,and inactive on BRD4BD2
T5434 ARV-825 Epigenetic Reader Domain
ARV-825, a heterobifunctional PROTAC (Proteolysis Targeting Chimera) that recruits BRD4 to the E3 ubiquitin ligase cereblon leading to fast, efficient, and prolonged degradation of BRD4 in all BL cell lines tested.
T21269 Sulfo-EMCS
Sulfo-EMCS is a heterobifunctional sulfhydryl- and amine-reactive crosslinker.
T24842 Sulfo-SIA Crosslinker Sulfo-SIA Cross-linker,Sulfo-SIA Cross linker
Sulfo-SIA Crosslinker is a non-cleavable, heterobifunctional protein crosslinker. Sulfo-SIA Crosslinker is useful in making antibody-drug conjugates.
T15395 GMBS Others
GMBS is a heterobifunctional cross-linker.
T24841 Sulfo-MBS Crosslinker Sulfo-MBS Cross linker,Sulfo-MBS Cross-linker
Sulfo-MBS Crosslinker is a non-cleavable, water-soluble, heterobifunctional protein crosslinking reagent. It is commonly used to crosslink haptens to carrier proteins and enzymes to antibodies.
T18725 Sulfo-LC-SPDP Others
Sulfo-LC-SPDP is a heterobifunctional crosslinker characterized by its thiol-cleavable and membrane impermeable properties.
T18734 Sulfo-SPP Others
Sulfo-SPP is a heterobifunctional, thiol-cleavable and membrane impermeable crosslinker.
T19568 Sulfo-SMPB sodium Others
Sulfo-SMPB sodium is a non-cleavable heterobifunctional chemical cross-linking reagent that combines N-hydroxysuccinimide ester and maleimide groups. This compound enables the covalent conjugation of molecules possessing...
T15883 M-PEG4-phosphonic acid ethyl ester Others
m-PEG4-phosphonic acid ethyl ester is a PEGylation-based linker for the design and synthesis of PROTACs, which are heterobifunctional molecules facilitating targeted protein degradation[1].
T19943 SMPB Crosslinker SMPB Cross linker,SMPB Cross-linker
SMPB crosslinker is a heterobifunctional protein crosslinking reagent that is reactive toward sulfhydryl and amino groups. The SMPB protein crosslinker is an extended chain length analog of MBS crosslinker. SMPB crosslin...
T39352 Piperidine-GNE-049-N-Boc
Piperidine-GNE-049-N-Boc is a ligand that specifically binds to the target protein dCBP, enabling it to be degraded by a selective and potent heterobifunctional degrader, p300/CBP.
T40144 CBP/p300 ligand 2
CBP/p300 ligand 2 is a selective ligand that binds to the target protein for PROTAC of dCBP-1, a potent and selective heterobifunctional degrader of p300/CBP.
T18189 M-PEG3-Sulfone-PEG4-propargyl Others
m-PEG3-Sulfone-PEG4-propargyl is a polyethylene glycol (PEG)-based prodrug-induced degradation (PROTAC) linker. It is utilized in the efficient synthesis of PROTACs, a class of heterobifunctional molecules designed to se...
T40036 Thalidomide-NH-PEG4-COOH Thalidomide-NH-PEG4-COOH
Thalidomide-NH-PEG4-COOH is a conjugate comprising an E3 ligase ligand-linker, utilized in the synthesis of dCBP-1. dCBP-1 itself functions as a powerful and selective heterobifunctional degrader targeting p300/CBP.
1 2
TargetMol