Powder: -20°C for 3 years | In solvent: -80°C for 1 year
m-PEG3-Sulfone-PEG4-propargyl is a polyethylene glycol (PEG)-based prodrug-induced degradation (PROTAC) linker. It is utilized in the efficient synthesis of PROTACs, a class of heterobifunctional molecules designed to selectively target and degrade specific protein targets[1].
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Description | m-PEG3-Sulfone-PEG4-propargyl is a polyethylene glycol (PEG)-based prodrug-induced degradation (PROTAC) linker. It is utilized in the efficient synthesis of PROTACs, a class of heterobifunctional molecules designed to selectively target and degrade specific protein targets[1]. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 426.52 |
Formula | C18H34O9S |
CAS No. | 2055041-02-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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m-PEG3-Sulfone-PEG4-propargyl 2055041-02-4 Others m PEG3 Sulfone PEG4 propargyl mPEG3SulfonePEG4propargyl m-PEG-3-Sulfone-PEG4-propargyl inhibitor inhibit