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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN6732 | Oenothein B | Apoptosis , HCV Protease , Antibacterial , Antifungal | |
Oenothein B is a specific inhibitor of poly(ADP-ribose) glycohydrolase. Oenothein B shows antioxidant, anti-inflammatory, antifungal, anti-HCV, and antitumor properties. | |||
T5967 | Ethacridine lactate | Acrinol,6,9-DIAMINO-2-ETHOXYACRIDINE LACTATE | Others , Antibacterial |
Ethacridine lactate (Acrinol) is a poly(ADP-ribose) glycohydrolase (PARG) inhibitor. | |||
T78401 | PNP-ADPr disodium | ADP-ribose-pNP disodium | |
pNP-ADPr disodium serves as a colorimetric substrate in the inaugural continuous assays of Poly(ADP-ribose) glycohydrolase (PARG) and ADP-ribosyl hydrolase 3 (ARH3) activities. It also facilitates research into poly(ADP-... | |||
T39365 | PDD00017238 | ||
PDD00017238 demonstrates a robust inhibitory effect on Poly(ADP-ribose) Glycohydrolase (PARG), displaying EC50 values of 40 nM in biochemical assay and 55 nM in cell POM assessment. | |||
T34271 | RBPI-3 | ||
RBPI-3 is a canonical poly(ADP-ribose) glycohydrolase. | |||
T12388 | PDD00031705 | Others | |
PDD00031705 is a benzimidazolone core cell-inactive Poly (ADP-ribose) glycohydrolase (PARG) inhibitor. | |||
T81546 | PARG-IN-4 | ||
PARG-IN-4 (Formula (A)), an orally active and cell-permeable inhibitor of poly(ADP-ribose) glycohydrolase (PARG), demonstrates effective inhibition of tumor growth in mouse models and is applicable in cancer research [1]... | |||
T41083 | PNP-ADPr | pNP-ADPr,ADP-ribose-pNP | |
pNP-ADPr is a colorimetric substrate employed in the first continuous activity assays for Poly(ADP-ribose) glycohydrolase (PARG) and ADP-ribosyl hydrolase 3 (ARH3). Its utilization facilitates research on poly(ADP-ribose... | |||
T61553 | ATPase-IN-2 | ||
ATPase-IN-2 is a compound that acts as an inhibitor of ATPase, with an IC50 value of 0.9 μM. It also inhibits the glycohydrolase activity of C. difficile toxin B (TcdB) with an AC50 value of 30.91 μM. ATPase-IN-2 is comm... | |||
T39356 | PDD00017272 | PDD-00017272 | Others |
PDD00017272 (34f) is a potent inhibitor of poly(ADP-ribose) glycohydrolase (PARG) with an EC50 value of 4.8 nM in biochemical assays and 9.2 nM in cellular POM. | |||
T73479 | JA2131 | ||
JA2131 is a small molecular inhibitor targeting Poly(ADP-ribose) Glycohydrolase (PARG) with an IC50 value of 0.4 μM. It modulates DNA damage responses, induces replication fork stalling, and leads to cancer cell death. | |||
T74510 | TFMU-ADPr | ||
TFMU-ADPr serves as a versatile substrate for assessing poly(ADP-ribose) glycohydrolase (PARG) activity, enabling direct measurement of total PAR hydrolase activity through the liberation of a fluorophore. Exhibiting exc... | |||
T74511 | TFMU-ADPr triethylamine | ||
TFMU-ADPr triethylamine, a versatile substrate for evaluating poly(ADP-ribose) glycohydrolase (PARG) activity, enables direct measurement of total PAR hydrolase activity through the liberation of a fluorophore. With outs... |