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Search Results for " glycohydrolase "

13

Compounds

Cat No. Product Name Synonyms Targets
TN6732 Oenothein B Apoptosis , HCV Protease , Antibacterial , Antifungal
Oenothein B is a specific inhibitor of poly(ADP-ribose) glycohydrolase. Oenothein B shows antioxidant, anti-inflammatory, antifungal, anti-HCV, and antitumor properties.
T5967 Ethacridine lactate Acrinol,6,9-DIAMINO-2-ETHOXYACRIDINE LACTATE Others , Antibacterial
Ethacridine lactate (Acrinol) is a poly(ADP-ribose) glycohydrolase (PARG) inhibitor.
T78401 PNP-ADPr disodium ADP-ribose-pNP disodium
pNP-ADPr disodium serves as a colorimetric substrate in the inaugural continuous assays of Poly(ADP-ribose) glycohydrolase (PARG) and ADP-ribosyl hydrolase 3 (ARH3) activities. It also facilitates research into poly(ADP-...
T39365 PDD00017238
PDD00017238 demonstrates a robust inhibitory effect on Poly(ADP-ribose) Glycohydrolase (PARG), displaying EC50 values of 40 nM in biochemical assay and 55 nM in cell POM assessment.
T34271 RBPI-3
RBPI-3 is a canonical poly(ADP-ribose) glycohydrolase.
T12388 PDD00031705 Others
PDD00031705 is a benzimidazolone core cell-inactive Poly (ADP-ribose) glycohydrolase (PARG) inhibitor.
T81546 PARG-IN-4
PARG-IN-4 (Formula (A)), an orally active and cell-permeable inhibitor of poly(ADP-ribose) glycohydrolase (PARG), demonstrates effective inhibition of tumor growth in mouse models and is applicable in cancer research [1]...
T41083 PNP-ADPr pNP-ADPr,ADP-ribose-pNP
pNP-ADPr is a colorimetric substrate employed in the first continuous activity assays for Poly(ADP-ribose) glycohydrolase (PARG) and ADP-ribosyl hydrolase 3 (ARH3). Its utilization facilitates research on poly(ADP-ribose...
T61553 ATPase-IN-2
ATPase-IN-2 is a compound that acts as an inhibitor of ATPase, with an IC50 value of 0.9 μM. It also inhibits the glycohydrolase activity of C. difficile toxin B (TcdB) with an AC50 value of 30.91 μM. ATPase-IN-2 is comm...
T39356 PDD00017272 PDD-00017272 Others
PDD00017272 (34f) is a potent inhibitor of poly(ADP-ribose) glycohydrolase (PARG) with an EC50 value of 4.8 nM in biochemical assays and 9.2 nM in cellular POM.
T73479 JA2131
JA2131 is a small molecular inhibitor targeting Poly(ADP-ribose) Glycohydrolase (PARG) with an IC50 value of 0.4 μM. It modulates DNA damage responses, induces replication fork stalling, and leads to cancer cell death.
T74510 TFMU-ADPr
TFMU-ADPr serves as a versatile substrate for assessing poly(ADP-ribose) glycohydrolase (PARG) activity, enabling direct measurement of total PAR hydrolase activity through the liberation of a fluorophore. Exhibiting exc...
T74511 TFMU-ADPr triethylamine
TFMU-ADPr triethylamine, a versatile substrate for evaluating poly(ADP-ribose) glycohydrolase (PARG) activity, enables direct measurement of total PAR hydrolase activity through the liberation of a fluorophore. With outs...
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