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Search Results for " glucocorticoids "

12

Compounds

Cat No. Product Name Synonyms Targets
T40808 Glucocorticoids receptor agonist 1
Glucocorticoids receptor agonist 1 (GRA-1) is a highly effective arylpyrazole-based compound that acts as an agonist for the glucocorticoid receptor. GRA-1 exhibits strong anti-inflammatory properties while maintaining i...
T40697 Glucocorticoids receptor agonist 2
Glucocorticoid receptor agonist 2 is a highly effective anti-inflammatory compound, derived from arylpyrazole, that actively binds to and activates the glucocorticoid receptor. This compound exhibits potent anti-inflamma...
T3316 Fluorometholone Fluoromethalone,Cortilet,Oxylone,Delmeson Glucocorticoid Receptor
Fluorometholone (Fluoromethalone) is a corticosteroid, most often used after laser-based refractive surgery. It is marketed under the brand names FML (Allergan) and Flarex (Alcon). Fluorometholone acetate ophthalmic susp...
T72814 11β-HSD1-IN-12 Dehydrogenase
11β-HSD1-IN-12 is an 11β-HSD1 inhibitor.11β-HSD1-IN-12 is implicated in the conversion of glucocorticoids in vivo and can be used to study metabolic syndrome and obesity.
TN1236 3',4',7-Trihydroxyisoflavone MAPK , JNK
3',4',7-Trihydroxyisoflavone is a soy isoflavone soy glycoside derivative and Cot (Tpl2/MAP3K8) and MKK4 inhibitor with anticancer, antiangiogenic and free radical scavenging properties.3',4',7-Trihydroxyisoflavone enhan...
T6509 Galeterone VN-124-1,TOK-001,VN/124-1,VN 124 P450 , Androgen Receptor
Galeterone (VN 124) is an orally bioavailable small-molecule androgen receptor modulator and CYP17 lyase inhibitor with potential antiandrogen activity. Galeterone exhibits three distinct mechanisms of action: 1) as an a...
T2548 Diflorasone Glucocorticoid Receptor
Diflorasone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive properties. Like other glucocorticoids, diflorasone enters the cell by diffusion across the cell membrane and binds to the glucocorti...
TJO2758 D-Glucuronic acid Aldehydo-D-Glucuronic Acid Others , Endogenous Metabolite
D-Glucuronic acid (Aldehydo-D-Glucuronic Acid) is a carboxylic acid with structural similarity to glucose with detoxifying activity. The xenobiotic metabolism of various substances such as drugs, pollutants, bilirubin, a...
T61593 11β-HSD1-IN-6
11β-HSD1-IN-6 is a potent inhibitor of 11β hydroxysteroid dehydrogenase enzymes (11β-HSDs). These enzymes are responsible for catalyzing the conversion of the active glucocorticoids, corticosterone or cortisol, to their ...
T11871 Loteprednol Etabonate D5 Others
Loteprednol Etabonate D5, a deuterium-labeled variant of Loteprednol etabonate (LE), is an orally active, anti-inflammatory soft steroid within a distinctive class of glucocorticoids. It is deployed in optometry and opht...
T62252 R-HP210
R-HP210 inhibits LPS-induced transcription of several pro-inflammatory genes (IL-1β, IL-6 and COX-2). r-HP210 has an IC50 value of 3.80 μM for NF-κB-mediated bolus trans-suppression. r-HP210 does not induce trans-activat...
T68808 11-Dehydrocorticosterone
11-Dehydrocorticosterone is an endogenous mineralocorticoid. It increases Na+/K+-ATPase mRNA expression in vascular smooth muscle cells and inhibits aldosterone action in B. marinus toad bladder tissue in a concentration...
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