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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T40808 | Glucocorticoids receptor agonist 1 | ||
Glucocorticoids receptor agonist 1 (GRA-1) is a highly effective arylpyrazole-based compound that acts as an agonist for the glucocorticoid receptor. GRA-1 exhibits strong anti-inflammatory properties while maintaining i... | |||
T40697 | Glucocorticoids receptor agonist 2 | ||
Glucocorticoid receptor agonist 2 is a highly effective anti-inflammatory compound, derived from arylpyrazole, that actively binds to and activates the glucocorticoid receptor. This compound exhibits potent anti-inflamma... | |||
T3316 | Fluorometholone | Fluoromethalone,Cortilet,Oxylone,Delmeson | Glucocorticoid Receptor |
Fluorometholone (Fluoromethalone) is a corticosteroid, most often used after laser-based refractive surgery. It is marketed under the brand names FML (Allergan) and Flarex (Alcon). Fluorometholone acetate ophthalmic susp... | |||
T72814 | 11β-HSD1-IN-12 | Dehydrogenase | |
11β-HSD1-IN-12 is an 11β-HSD1 inhibitor.11β-HSD1-IN-12 is implicated in the conversion of glucocorticoids in vivo and can be used to study metabolic syndrome and obesity. | |||
TN1236 | 3',4',7-Trihydroxyisoflavone | MAPK , JNK | |
3',4',7-Trihydroxyisoflavone is a soy isoflavone soy glycoside derivative and Cot (Tpl2/MAP3K8) and MKK4 inhibitor with anticancer, antiangiogenic and free radical scavenging properties.3',4',7-Trihydroxyisoflavone enhan... | |||
T6509 | Galeterone | VN-124-1,TOK-001,VN/124-1,VN 124 | P450 , Androgen Receptor |
Galeterone (VN 124) is an orally bioavailable small-molecule androgen receptor modulator and CYP17 lyase inhibitor with potential antiandrogen activity. Galeterone exhibits three distinct mechanisms of action: 1) as an a... | |||
T2548 | Diflorasone | Glucocorticoid Receptor | |
Diflorasone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive properties. Like other glucocorticoids, diflorasone enters the cell by diffusion across the cell membrane and binds to the glucocorti... | |||
TJO2758 | D-Glucuronic acid | Aldehydo-D-Glucuronic Acid | Others , Endogenous Metabolite |
D-Glucuronic acid (Aldehydo-D-Glucuronic Acid) is a carboxylic acid with structural similarity to glucose with detoxifying activity. The xenobiotic metabolism of various substances such as drugs, pollutants, bilirubin, a... | |||
T61593 | 11β-HSD1-IN-6 | ||
11β-HSD1-IN-6 is a potent inhibitor of 11β hydroxysteroid dehydrogenase enzymes (11β-HSDs). These enzymes are responsible for catalyzing the conversion of the active glucocorticoids, corticosterone or cortisol, to their ... | |||
T11871 | Loteprednol Etabonate D5 | Others | |
Loteprednol Etabonate D5, a deuterium-labeled variant of Loteprednol etabonate (LE), is an orally active, anti-inflammatory soft steroid within a distinctive class of glucocorticoids. It is deployed in optometry and opht... | |||
T62252 | R-HP210 | ||
R-HP210 inhibits LPS-induced transcription of several pro-inflammatory genes (IL-1β, IL-6 and COX-2). r-HP210 has an IC50 value of 3.80 μM for NF-κB-mediated bolus trans-suppression. r-HP210 does not induce trans-activat... | |||
T68808 | 11-Dehydrocorticosterone | ||
11-Dehydrocorticosterone is an endogenous mineralocorticoid. It increases Na+/K+-ATPase mRNA expression in vascular smooth muscle cells and inhibits aldosterone action in B. marinus toad bladder tissue in a concentration... |