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Selenazofurin

Catalog No. T28744 CAS 83705-13-9

Synonyms: BRN 4198668, CI-935, CI 935, CI935

Selenazofurin is an antiviral compound. Selenazofurin inhibits the cytopathic effect and yield of influenza A/NWS/33 virus with 50% effective dose ranges of 0.7 to 1.4 micrograms/ml.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Selenazofurin, CAS 83705-13-9

Pack Size	Availability	Price/USD
25 mg	6-8 weeks	$ 1,670.00
50 mg	6-8 weeks	$ 2,180.00
100 mg	6-8 weeks	$ 2,800.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Selenazofurin is an antiviral compound. Selenazofurin inhibits the cytopathic effect and yield of influenza A/NWS/33 virus with 50% effective dose ranges of 0.7 to 1.4 micrograms/ml.

Synonyms	BRN 4198668, CI-935, CI 935, CI935
Molecular Weight	307.16
Formula	C9H12N2O5Se
CAS No.	83705-13-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Pogrebniak A, Hasmann M, Schemainda I, Pelka-Fleischer R, Nuessler V. Cytoprotective features of selenazofurin in hematopoietic cells. Int J Clin Pharmacol Ther. 2002 Aug;40(8):368-75. PubMed PMID: 12467305. 2. Franchetti P, Cappellacci L, Sheikha GA, Jayaram HN, Gurudutt VV, Sint T, Schneider BP, Jones WD, Goldstein BM, Perra G, De Montis A, Loi AG, La Colla P, Grifantini M. Synthesis, structure, and antiproliferative activity of selenophenfurin, an inosine 5'-monophosphate dehydrogenase inhibitor analogue of selenazofurin. J Med Chem. 1997 May 23;40(11):1731-7. PubMed PMID: 9171883. 3. Gharehbaghi K, Sreenath A, Hao Z, Paull KD, Szekeres T, Cooney DA, Krohn K, Jayaram HN. Comparison of biochemical parameters of benzamide riboside, a new inhibitor of IMP dehydrogenase, with tiazofurin and selenazofurin. Biochem Pharmacol. 1994 Oct 7;48(7):1413-9. PubMed PMID: 7945441. 4. Smee DF, Gilbert J, Leonhardt JA, Barnett BB, Huggins JH, Sidwell RW. Treatment of lethal Pichinde virus infections in weanling LVG/Lak hamsters with ribavirin, ribamidine, selenazofurin, and ampligen. Antiviral Res. 1993 Jan;20(1):57-70. PubMed PMID: 8384433.

Dose Conversion

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
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The answer of 19.713 mg appears in the Mass box

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The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Selenazofurin 83705-13-9 BRN 4198668 BRN4198668 CI-935 CI 935 BRN-4198668 CI935 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.